probenecid has been researched along with Alcohol Drinking in 7 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probenecid was also detected in vitreous and bile." | 1.28 | A death involving probenecid. ( Crump, K; Drummer, OH; McIntyre, IM; Roberts, AN, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tunstall, BJ | 1 |
| Lorrai, I | 1 |
| McConnell, SA | 1 |
| Gazo, KL | 1 |
| Zallar, LJ | 1 |
| de Guglielmo, G | 1 |
| Hoang, I | 1 |
| Haass-Koffler, CL | 1 |
| Repunte-Canonigo, V | 1 |
| Koob, GF | 1 |
| Vendruscolo, LF | 1 |
| Sanna, PP | 1 |
| Kaneko, K | 1 |
| Fujimori, S | 1 |
| Yamanaka, H | 1 |
| Akaoka, I | 1 |
| Gibson, T | 2 |
| Kilbourn, K | 1 |
| Horner, I | 1 |
| Simmonds, HA | 1 |
| McIntyre, IM | 1 |
| Crump, K | 1 |
| Roberts, AN | 1 |
| Drummer, OH | 1 |
| Grahame, R | 1 |
| Ahtee, L | 1 |
| Eriksson, K | 1 |
| Roy, RB | 1 |
| Laird, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Probenecid as Pharmacotherapy for Alcohol Use Disorder[NCT04218357] | Phase 1 | 34 participants (Anticipated) | Interventional | 2020-12-02 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for probenecid and Alcohol Drinking
| Article | Year |
|---|---|
Effect of hypouricemic agents on serum carbohydrate-deficient transferrin in gouty patients.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Allopurinol; Benzbromarone; Chromatography, Ion Ex | 1994 |
6 other studies available for probenecid and Alcohol Drinking
| Article | Year |
|---|---|
Probenecid Reduces Alcohol Drinking in Rodents. Is Pannexin1 a Novel Therapeutic Target for Alcohol Use Disorder?
Topics: Adjuvants, Pharmaceutic; Alcohol Drinking; Alcoholism; Animals; Connexins; Dose-Response Relationshi | 2019 |
Mechanism and treatment of hypertriglyceridaemia in gout.
Topics: Alcohol Drinking; Allopurinol; Cholesterol; Gout; Humans; Hyperlipidemias; Male; Middle Aged; Obesit | 1979 |
A death involving probenecid.
Topics: Adult; Alcohol Drinking; Bile; Cardiomegaly; Drug Overdose; Ethanol; Humans; Liver; Male; Probenecid | 1992 |
Gout and hyperlipidaemia.
Topics: Adult; Aged; Alcohol Drinking; Allopurinol; Aspartate Aminotransferases; Body Height; Body Weight; C | 1974 |
5-Hydroxytryptamine and 5-hydroxyindolylacetic acid content in brain of rat strains selected for their alcohol intake.
Topics: Alcohol Drinking; Alcoholism; Animals; Body Temperature; Brain; Brain Chemistry; Disease Models, Ani | 1972 |
Comparison of procaine penicillin alone with ampicillin plus probenecid in the treatment of gonorrhoea in the male.
Topics: Administration, Oral; Alcohol Drinking; Ampicillin; Drug Therapy, Combination; England; Female; Gono | 1974 |