probenecid has been researched along with Aging in 17 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (70.59) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CONSTANT, MA | 1 |
| FALCH, J | 1 |
| KUZELL, WC | 1 |
| GLOVER, RP | 1 |
| GIBBS, JO | 1 |
| BLAU, RA | 1 |
| Verbeeck, RK | 1 |
| Wallace, SM | 1 |
| Loewen, GR | 1 |
| Kim, CS | 1 |
| O'Tuama, LA | 1 |
| Mann, JD | 1 |
| Roe, CR | 1 |
| Goodnick, PJ | 1 |
| Evans, HE | 1 |
| Dunner, DL | 1 |
| Fieve, RR | 1 |
| Venero, JL | 1 |
| Machado, A | 1 |
| Cano, J | 1 |
| Krunic, N | 2 |
| Adamson, SL | 2 |
| Bishai, I | 1 |
| Coceani, F | 2 |
| Bräunlich, H | 2 |
| Bonow, A | 1 |
| Schröter, S | 1 |
| Stopp, M | 1 |
| Hartwich, R | 1 |
| Norling, LL | 1 |
| Vaughan, CA | 1 |
| Chevalier, RL | 1 |
| Johanson, CE | 1 |
| Parandoosh, Z | 1 |
| Dyas, ML | 1 |
| Yesavage, JA | 1 |
| Berger, PA | 2 |
| Stahl, SM | 1 |
| Thiemann, S | 1 |
| Faull, KF | 1 |
| Barchas, JD | 1 |
| Ebadi, MS | 1 |
| Rennick, BR | 1 |
| Straus, B | 1 |
2 reviews available for probenecid and Aging
| Article | Year |
|---|---|
Ontogenetic alterations of vitamin B 6 metabolism in rat brain--evidence of acceleration of its turnover rate.
Topics: Aging; Animals; Animals, Newborn; Biodegradation, Environmental; Biotransformation; Brain; Brain Che | 1972 |
Renal excretion of drugs: tubular transport and metabolism.
Topics: Aging; Aminohippuric Acids; Animals; Biogenic Amines; Biological Transport, Active; Catechols; Cell | 1972 |
15 other studies available for probenecid and Aging
| Article | Year |
|---|---|
PHOSPHATE AND PROTEIN CONCENTRATIONS OF INTRAOCULAR FLUIDS. I. EFFECT OF CARBONIC ANHYDRASE INHIBITION IN YOUNG AND OLD RABBITS.
Topics: Aging; Animals; Aqueous Humor; Ascorbic Acid; Bicarbonates; Blood Chemical Analysis; Carbonic Anhydr | 1963 |
EFFECT OF SULFINPYRAZONE ON SERUM URIC ACID IN GOUT. A LONG-TERM STUDY.
Topics: Adolescent; Aging; Blood; Drug Therapy; Geriatrics; Gout; Longitudinal Studies; Metabolism; Phenylbu | 1964 |
Reduced elimination of ketoprofen in the elderly is not necessarily due to impaired glucuronidation.
Topics: Aged; Aging; Clofibric Acid; Diflunisal; Glucuronates; Humans; Ketoprofen; Phenylpropionates; Proben | 1984 |
Saturable accumulation of the anionic herbicide, 2,4-dichlorophenoxyacetic acid (2,4-D), by rabbit choroid plexus: early developmental origin and interaction with salicylates.
Topics: 2,4-Dichlorophenoxyacetic Acid; Acetaminophen; Aging; Animals; Animals, Newborn; Biological Transpor | 1983 |
Amino acid concentrations in cerebrospinal fluid: effects of aging, depression, and probenecid.
Topics: Adult; Aging; Amino Acids; Bipolar Disorder; Depression; Female; Humans; Male; Middle Aged; Probenec | 1980 |
Effect of ageing on monoamine turnover in the prefrontal cortex of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hy | 1993 |
Prostaglandin uptake and catabolism by the choroid plexus during development in sheep.
Topics: Aging; Animals; Animals, Newborn; Biological Transport; Choroid Plexus; Dinoprost; Dinoprostone; Emb | 1997 |
Differential uptake and catabolism of prostaglandin (PG)E(2) versus PGF(2alpha) in the sheep choroid plexus during development.
Topics: Adult; Aging; Animals; Biological Transport; Cerebral Ventricles; Choroid Plexus; Dinoprost; Dinopro | 2000 |
Age-dependence of renal tubular reabsorption of nitrofurantoin.
Topics: Absorption; Aging; Animals; Diuresis; Female; Hydrogen-Ion Concentration; Kidney Tubules; Nitrofuran | 1978 |
Enhancement of p-aminohippurate accumulation in renal cortical slices after repeated administrations of various organic anionic drugs to rats of different ages.
Topics: Aging; Aminohippuric Acids; Animals; Animals, Newborn; Cycloheximide; Cyclopenthiazide; Female; Kidn | 1978 |
Maturation of cGMP response to ANP by isolated glomeruli.
Topics: Aging; Animals; Animals, Suckling; Atrial Natriuretic Factor; Cyclic GMP; Female; In Vitro Technique | 1992 |
Maturational differences in acetazolamide-altered pH and HCO3 of choroid plexus, cerebrospinal fluid, and brain.
Topics: Acetazolamide; Acid-Base Equilibrium; Aging; Animals; Bicarbonates; Blood; Brain; Choroid Plexus; Di | 1992 |
Correction to a 1980 article on CSF lactate and age.
Topics: Aging; Humans; Lactates; Lactic Acid; Probenecid | 1989 |
Neurochemistry of dopamine in Huntington's dementia and normal aging.
Topics: Adult; Aged; Aging; Brain; Dementia; Dopamine; Homovanillic Acid; Humans; Huntington Disease; Male; | 1986 |
Problems and progress in geriatrics.
Topics: Acute Disease; Aged; Aging; Calcitonin; Cardiovascular Diseases; Chronic Disease; Diabetic Coma; Dia | 1968 |