probenecid has been researched along with Acute Kidney Injury in 14 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Because the renal biopsy revealed acute tubular necrosis without uric acid crystals, the ARF of this patient might be due to oxygen free radicals resulting from exercise stress and hypouricemia." | 3.70 | Exercise-induced acute renal failure in a patient with renal hypouricemia. ( Abe, T; Oda, Y; Watanabe, T, 2000) |
| "Acute renal failure is one of the most serious complications of envenoming resulting from Crotalus durissus terrificus bites." | 1.37 | Allopurinol reduces the lethality associated with acute renal failure induced by Crotalus durissus terrificus snake venom: comparison with probenecid. ( Frezzatti, R; Silveira, PF, 2011) |
| "Acute renal failure was induced by occlusion of bilateral renal arteries for 60 min, and the motor activity and brain monoamine turnover were examined 48 h later." | 1.31 | Uraemia suppresses central dopaminergic metabolism and impairs motor activity in rats. ( Adachi, N; Arai, T; Deshpande, G; Lei, B; Nagaro, T; Seyfried, FJ; Shimizu, I, 2001) |
| "Phenacetin pretreatment (597 mg/kg) was less effective, while paracetamol (503 mg/kg) was without effect in this regard." | 1.26 | Studies on the modification of renal lesions due to aspirin and oxyphenbutazone in the rat and the effects on the kidney of 2:4 dinitrophenol. ( Arnold, L; Collins, C; Starmer, GA, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (64.29) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frezzatti, R | 1 |
| Silveira, PF | 1 |
| D ANGLEJEAN, G | 1 |
| Tanaka, M | 1 |
| Itoh, K | 1 |
| Matsushita, K | 2 |
| Wakita, N | 1 |
| Adachi, M | 1 |
| Nonoguchi, H | 1 |
| Kitamura, K | 1 |
| Hosoyamada, M | 1 |
| Endou, H | 1 |
| Tomita, K | 1 |
| Miwa, T | 1 |
| Decaux, G | 1 |
| Soupart, A | 1 |
| Musch, W | 1 |
| Hannotier, P | 1 |
| Prospert, F | 1 |
| Watanabe, T | 1 |
| Abe, T | 1 |
| Oda, Y | 1 |
| Adachi, N | 1 |
| Lei, B | 1 |
| Deshpande, G | 1 |
| Seyfried, FJ | 1 |
| Shimizu, I | 1 |
| Nagaro, T | 1 |
| Arai, T | 1 |
| Arnold, L | 1 |
| Collins, C | 1 |
| Starmer, GA | 1 |
| Tune, BM | 2 |
| Tungsanga, K | 1 |
| Kateruttanakul, P | 1 |
| Sitprija, V | 1 |
| Elfarra, AA | 1 |
| Baggs, RB | 1 |
| Anders, MW | 1 |
| Scott, JT | 1 |
| O'Brien, PK | 1 |
14 other studies available for probenecid and Acute Kidney Injury
| Article | Year |
|---|---|
Allopurinol reduces the lethality associated with acute renal failure induced by Crotalus durissus terrificus snake venom: comparison with probenecid.
Topics: Acute Kidney Injury; Allopurinol; Animals; Antimetabolites; Crotalus; Male; Mice; Probenecid; Snake | 2011 |
[ASSESSMENT OF 172 CASES OF CHRONIC GOUT TREATED BY PROBENECID FOR 10 YEARS].
Topics: Acute Kidney Injury; Arthritis, Gouty; Gout; Humans; Kidney Calculi; Probenecid; Renal Insufficiency | 1963 |
Two male siblings with hereditary renal hypouricemia and exercise-induced ARF.
Topics: Acute Kidney Injury; Adult; Back Pain; Carrier Proteins; Codon, Nonsense; Creatinine; Exercise; Exon | 2003 |
[Alteration in furosemide metabolism in renal failure rat (author's transl)].
Topics: Acute Kidney Injury; Animals; Depression, Chemical; Furosemide; Kinetics; Male; Probenecid; Rats | 1980 |
Restoration of the uricosuric effect of probenecid after triglycylvasopressine administration in a gouty patient.
Topics: Absorption; Acute Kidney Injury; Adult; Anti-Inflammatory Agents; Benzbromarone; Fludrocortisone; Go | 1998 |
Exercise-induced acute renal failure in a patient with renal hypouricemia.
Topics: Acute Kidney Injury; Child; Creatinine; Exercise; Follow-Up Studies; Humans; Kidney; Kidney Tubules; | 2000 |
Uraemia suppresses central dopaminergic metabolism and impairs motor activity in rats.
Topics: Acute Kidney Injury; alpha-Methyltyrosine; Animals; Brain Chemistry; Coma; Confusion; Corpus Striatu | 2001 |
Studies on the modification of renal lesions due to aspirin and oxyphenbutazone in the rat and the effects on the kidney of 2:4 dinitrophenol.
Topics: Acetaminophen; Acute Kidney Injury; Animals; Aspirin; Dinitrophenols; Female; Kidney Tubular Necrosi | 1976 |
Relationship between the transport and toxicity of cephalosporins in the kidney.
Topics: Acute Kidney Injury; Aminohippuric Acids; Animals; Animals, Newborn; Biological Transport; Cefazolin | 1975 |
The renal handling of urate in acute renal failure patients with high urine uric acid/urine creatinine concentration ratio.
Topics: Acute Kidney Injury; Adult; Creatine; Female; Humans; Kidney Tubules; Male; Middle Aged; Probenecid; | 1988 |
Structure-nephrotoxicity relationships of S-(2-chloroethyl)-DL-cysteine and analogs: role for an episulfonium ion.
Topics: Acute Kidney Injury; Alanine Transaminase; Animals; Blood Urea Nitrogen; Cysteine; Glycosuria; Ions; | 1985 |
Effect of organic acid transport inhibitors on renal cortical uptake and proximal tubular toxicity of cephaloridine.
Topics: Acute Kidney Injury; Animals; Biological Transport; Cephaloridine; Female; Glomerular Filtration Rat | 1972 |
Probenecid, nephrotic syndrome, and renal failure.
Topics: Acute Kidney Injury; Aged; Edema; Gout; Humans; Male; Middle Aged; Nephrotic Syndrome; Probenecid; P | 1968 |
Probenecid and renal failure.
Topics: Acute Kidney Injury; Edema; Humans; Probenecid; Proteinuria | 1968 |