Page last updated: 2024-11-03

probenecid and Acute Kidney Failure

probenecid has been researched along with Acute Kidney Failure in 14 studies

Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.

Research Excerpts

ExcerptRelevanceReference
" Because the renal biopsy revealed acute tubular necrosis without uric acid crystals, the ARF of this patient might be due to oxygen free radicals resulting from exercise stress and hypouricemia."3.70Exercise-induced acute renal failure in a patient with renal hypouricemia. ( Abe, T; Oda, Y; Watanabe, T, 2000)
"Acute renal failure is one of the most serious complications of envenoming resulting from Crotalus durissus terrificus bites."1.37Allopurinol reduces the lethality associated with acute renal failure induced by Crotalus durissus terrificus snake venom: comparison with probenecid. ( Frezzatti, R; Silveira, PF, 2011)
"Acute renal failure was induced by occlusion of bilateral renal arteries for 60 min, and the motor activity and brain monoamine turnover were examined 48 h later."1.31Uraemia suppresses central dopaminergic metabolism and impairs motor activity in rats. ( Adachi, N; Arai, T; Deshpande, G; Lei, B; Nagaro, T; Seyfried, FJ; Shimizu, I, 2001)
"Phenacetin pretreatment (597 mg/kg) was less effective, while paracetamol (503 mg/kg) was without effect in this regard."1.26Studies on the modification of renal lesions due to aspirin and oxyphenbutazone in the rat and the effects on the kidney of 2:4 dinitrophenol. ( Arnold, L; Collins, C; Starmer, GA, 1976)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19909 (64.29)18.7374
1990's1 (7.14)18.2507
2000's3 (21.43)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frezzatti, R1
Silveira, PF1
D ANGLEJEAN, G1
Tanaka, M1
Itoh, K1
Matsushita, K2
Wakita, N1
Adachi, M1
Nonoguchi, H1
Kitamura, K1
Hosoyamada, M1
Endou, H1
Tomita, K1
Miwa, T1
Decaux, G1
Soupart, A1
Musch, W1
Hannotier, P1
Prospert, F1
Watanabe, T1
Abe, T1
Oda, Y1
Adachi, N1
Lei, B1
Deshpande, G1
Seyfried, FJ1
Shimizu, I1
Nagaro, T1
Arai, T1
Arnold, L1
Collins, C1
Starmer, GA1
Tune, BM2
Tungsanga, K1
Kateruttanakul, P1
Sitprija, V1
Elfarra, AA1
Baggs, RB1
Anders, MW1
Scott, JT1
O'Brien, PK1

Other Studies

14 other studies available for probenecid and Acute Kidney Failure

ArticleYear
Allopurinol reduces the lethality associated with acute renal failure induced by Crotalus durissus terrificus snake venom: comparison with probenecid.
    PLoS neglected tropical diseases, 2011, Volume: 5, Issue:9

    Topics: Acute Kidney Injury; Allopurinol; Animals; Antimetabolites; Crotalus; Male; Mice; Probenecid; Snake

2011
[ASSESSMENT OF 172 CASES OF CHRONIC GOUT TREATED BY PROBENECID FOR 10 YEARS].
    France Medecine, 1963, Volume: 26

    Topics: Acute Kidney Injury; Arthritis, Gouty; Gout; Humans; Kidney Calculi; Probenecid; Renal Insufficiency

1963
Two male siblings with hereditary renal hypouricemia and exercise-induced ARF.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:6

    Topics: Acute Kidney Injury; Adult; Back Pain; Carrier Proteins; Codon, Nonsense; Creatinine; Exercise; Exon

2003
[Alteration in furosemide metabolism in renal failure rat (author's transl)].
    Nihon Jinzo Gakkai shi, 1980, Volume: 22, Issue:8

    Topics: Acute Kidney Injury; Animals; Depression, Chemical; Furosemide; Kinetics; Male; Probenecid; Rats

1980
Restoration of the uricosuric effect of probenecid after triglycylvasopressine administration in a gouty patient.
    Clinical nephrology, 1998, Volume: 50, Issue:4

    Topics: Absorption; Acute Kidney Injury; Adult; Anti-Inflammatory Agents; Benzbromarone; Fludrocortisone; Go

1998
Exercise-induced acute renal failure in a patient with renal hypouricemia.
    Pediatric nephrology (Berlin, Germany), 2000, Volume: 14, Issue:8-9

    Topics: Acute Kidney Injury; Child; Creatinine; Exercise; Follow-Up Studies; Humans; Kidney; Kidney Tubules;

2000
Uraemia suppresses central dopaminergic metabolism and impairs motor activity in rats.
    Intensive care medicine, 2001, Volume: 27, Issue:10

    Topics: Acute Kidney Injury; alpha-Methyltyrosine; Animals; Brain Chemistry; Coma; Confusion; Corpus Striatu

2001
Studies on the modification of renal lesions due to aspirin and oxyphenbutazone in the rat and the effects on the kidney of 2:4 dinitrophenol.
    Pathology, 1976, Volume: 8, Issue:3

    Topics: Acetaminophen; Acute Kidney Injury; Animals; Aspirin; Dinitrophenols; Female; Kidney Tubular Necrosi

1976
Relationship between the transport and toxicity of cephalosporins in the kidney.
    The Journal of infectious diseases, 1975, Volume: 132, Issue:2

    Topics: Acute Kidney Injury; Aminohippuric Acids; Animals; Animals, Newborn; Biological Transport; Cefazolin

1975
The renal handling of urate in acute renal failure patients with high urine uric acid/urine creatinine concentration ratio.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1988, Volume: 71, Issue:1

    Topics: Acute Kidney Injury; Adult; Creatine; Female; Humans; Kidney Tubules; Male; Middle Aged; Probenecid;

1988
Structure-nephrotoxicity relationships of S-(2-chloroethyl)-DL-cysteine and analogs: role for an episulfonium ion.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:2

    Topics: Acute Kidney Injury; Alanine Transaminase; Animals; Blood Urea Nitrogen; Cysteine; Glycosuria; Ions;

1985
Effect of organic acid transport inhibitors on renal cortical uptake and proximal tubular toxicity of cephaloridine.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 181, Issue:2

    Topics: Acute Kidney Injury; Animals; Biological Transport; Cephaloridine; Female; Glomerular Filtration Rat

1972
Probenecid, nephrotic syndrome, and renal failure.
    Annals of the rheumatic diseases, 1968, Volume: 27, Issue:3

    Topics: Acute Kidney Injury; Aged; Edema; Gout; Humans; Male; Middle Aged; Nephrotic Syndrome; Probenecid; P

1968
Probenecid and renal failure.
    British medical journal, 1968, Sep-07, Volume: 3, Issue:5618

    Topics: Acute Kidney Injury; Edema; Humans; Probenecid; Proteinuria

1968