probenecid has been researched along with Acute Disease in 60 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Acute Disease: Disease having a short and relatively severe course.
Excerpt | Relevance | Reference |
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"The object of this randomized study was to compare the safety and efficacy of oral ofloxacin, 400 mg twice daily for 10 days, versus intramuscular cefoxitin, 2 gm, plus oral probenecid, 1 gm, followed by oral doxycycline, 100 mg twice daily for 10 days, in the outpatient treatment of uncomplicated acute salpingitis." | 9.07 | A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis. ( Bawdon, RE; Cox, SM; Heard, MC; Nobles, BJ; Theriot, SK; Wendel, GD, 1991) |
"We treated 142 patients with acute uncomplicated gonorrhea with a single oral dose of epiciline-probenecid." | 7.67 | [Uncomplicated acute male and female gonorrhea: treatment with a single oral dose of epicillin-probenecid]. ( García, J; Leone, A; Maldonado, A; Riedel, I; Rojas, B; Salvo, A, 1989) |
"To evaluate guidelines for outpatient treatment of acute pelvic inflammatory disease recommended by the Center for Disease Control we studied 197 afflicted women." | 5.26 | Evaluation of tetracycline or penicillin and ampicillin for treatment of acute pelvic inflammatory disease. ( Cunningham, FG; Gilstrap, LC; Hauth, JC; Herbert, WN; Kappus, SS; Strong, JD; Wilson, RH, 1977) |
"The object of this randomized study was to compare the safety and efficacy of oral ofloxacin, 400 mg twice daily for 10 days, versus intramuscular cefoxitin, 2 gm, plus oral probenecid, 1 gm, followed by oral doxycycline, 100 mg twice daily for 10 days, in the outpatient treatment of uncomplicated acute salpingitis." | 5.07 | A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis. ( Bawdon, RE; Cox, SM; Heard, MC; Nobles, BJ; Theriot, SK; Wendel, GD, 1991) |
"Each of 201 men with symptoms and signs of acute urethritis was randomly assigned to one of two treatment regimens: ampicillin (2g) plus probenecid (1g), or sulphamethoxazole-trimethoprim (SMX-TMP) (sulphamethoxazole 1600 mg plus trimethoprim 320 mg) four tablets twice daily for two days." | 5.05 | Treatment of acute gonococcal urethritis in men with simultaneous infection with Chlamydia trachomatis. ( Bjerk, O; Csángó, PA; Gundersen, T; Jagars, G; Salveson, A, 1984) |
"Gout is a clinical syndrome encompassing a group of metabolic diseases that are all characterized by abnormal uric acid metabolism." | 4.77 | Hyperuricemia and gout. ( German, DC; Holmes, EW, 1986) |
"We treated 142 patients with acute uncomplicated gonorrhea with a single oral dose of epiciline-probenecid." | 3.67 | [Uncomplicated acute male and female gonorrhea: treatment with a single oral dose of epicillin-probenecid]. ( García, J; Leone, A; Maldonado, A; Riedel, I; Rojas, B; Salvo, A, 1989) |
"For control of acute episodes of gout, administration of a full course of colchicine is the preferred method of therapy." | 3.66 | Treating gout: successful methods of prevention and control. ( Talbott, JH, 1978) |
"The metabolites of serotonin, dopamine, and norepinephrine, 5-hydroxyindoleacetic acid (5HIAA), homovanillic acid (HVA), and 3-methoxy-4-hydroxy-phenylethylene glycol (MHPG), respectively, were studied in cerebrospinal fluid of patients with acute schizophrenia." | 3.65 | Cerebrospinal fluid amine metabolites in acute schizophrenia. ( Carpenter, WT; Fink, E; Goodwin, FK; Post, RM, 1975) |
"Of 53 patients with acute uncomplicated gonorrhea treated with amoxicillin 2 g and probenecid 1 g orally as a single administration, six failed to return for follow-up examination, 10 developed postgonococcal urethritis and one was a treatment failure." | 3.65 | Oral amoxicillin in acute uncomplicated gonorrhea. ( Bayne, L; Ogilvie, RI; Ruedy, J; Tamblyn, D, 1974) |
"Probenecid pretreatment promoted an elevation in the urinary 16-hr excretion of APAP and a diminution in the plasma levels attained by APAP." | 1.30 | Probenecid protects against In vivo acetaminophen-induced nephrotoxicity in male Wistar rats. ( Elías, MM; Monasterolo, LA; Trumper, L, 1998) |
"To evaluate guidelines for outpatient treatment of acute pelvic inflammatory disease recommended by the Center for Disease Control we studied 197 afflicted women." | 1.26 | Evaluation of tetracycline or penicillin and ampicillin for treatment of acute pelvic inflammatory disease. ( Cunningham, FG; Gilstrap, LC; Hauth, JC; Herbert, WN; Kappus, SS; Strong, JD; Wilson, RH, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 50 (83.33) | 18.7374 |
1990's | 3 (5.00) | 18.2507 |
2000's | 7 (11.67) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
LAPORTE, A | 1 |
TANZER, J | 1 |
ROSA, J | 1 |
Sowunmi, A | 2 |
Fehintola, FA | 2 |
Adedeji, AA | 2 |
Gbotosho, GO | 1 |
Falade, CO | 1 |
Tambo, E | 1 |
Fateye, BA | 2 |
Happi, TC | 1 |
Oduola, AM | 1 |
Das, R | 1 |
Bingham, JS | 1 |
Ridgway, G | 1 |
Oriel, JD | 1 |
Csángó, PA | 1 |
Salveson, A | 1 |
Gundersen, T | 2 |
Jagars, G | 1 |
Bjerk, O | 1 |
García, J | 3 |
Arroyave, R | 2 |
Maldonado, A | 3 |
Dillon, JR | 1 |
Fich, F | 1 |
Salvo, A | 2 |
Villalobos, D | 3 |
Vicent, P | 1 |
Berger, RE | 1 |
van Gelderen, CJ | 1 |
Henretig, FM | 1 |
Bollet, AJ | 1 |
Trumper, L | 1 |
Monasterolo, LA | 1 |
Elías, MM | 1 |
Rao, PP | 1 |
Mopkar, O | 1 |
Desai, A | 1 |
Petroske, E | 1 |
Meredith, GE | 1 |
Callen, S | 1 |
Totterdell, S | 1 |
Lau, YS | 1 |
Tsimberidou, AM | 1 |
Paterakis, G | 1 |
Androutsos, G | 1 |
Anagnostopoulos, N | 1 |
Galanopoulos, A | 1 |
Kalmantis, T | 1 |
Meletis, J | 1 |
Rombos, Y | 1 |
Sagriotis, A | 1 |
Symeonidis, A | 1 |
Tiniakou, M | 1 |
Zoumbos, N | 1 |
Yataganas, X | 1 |
Gröbner, W | 1 |
Walter-Sack, I | 1 |
Gilliet, F | 2 |
Boss, GR | 1 |
Seegmiller, JE | 1 |
Cunningham, FG | 1 |
Hauth, JC | 1 |
Strong, JD | 1 |
Herbert, WN | 1 |
Gilstrap, LC | 1 |
Wilson, RH | 1 |
Kappus, SS | 1 |
St John, RK | 1 |
Talbott, JH | 1 |
Price, JD | 1 |
Fluker, JL | 1 |
Meheus, AZ | 1 |
Mubiligi, V | 1 |
Vandenberghe, G | 1 |
Bunnag, S | 1 |
Sucharit, S | 1 |
Chow, AW | 1 |
Soll, BA | 1 |
Targan, SR | 1 |
Buze, LB | 1 |
Bowers, MB | 1 |
Post, RM | 1 |
Fink, E | 1 |
Carpenter, WT | 1 |
Goodwin, FK | 1 |
Lassus, A | 1 |
Abath Filho, L | 1 |
Santos Júnior, MF | 1 |
Belli, L | 1 |
Wendel, GD | 1 |
Cox, SM | 1 |
Bawdon, RE | 1 |
Theriot, SK | 1 |
Heard, MC | 1 |
Nobles, BJ | 1 |
Leone, A | 1 |
Rojas, B | 1 |
Riedel, I | 1 |
Melby, K | 1 |
Ulshagen, K | 1 |
Smith, CR | 1 |
German, DC | 1 |
Holmes, EW | 1 |
Lim, KB | 1 |
Thirumoorthy, T | 1 |
Lee, CT | 1 |
Sng, EH | 1 |
Tan, T | 1 |
Malmborg, AS | 1 |
Molin, L | 1 |
Nyström, B | 1 |
Gurwith, MJ | 1 |
McGinnis, S | 1 |
Ronald, AR | 1 |
Henry, R | 1 |
Bayne, L | 1 |
Tamblyn, D | 1 |
Ruedy, J | 1 |
Ogilvie, RI | 1 |
Brown, ST | 1 |
McMinn, T | 1 |
Braff, EH | 1 |
Gutman, AB | 1 |
Petzoldt, D | 1 |
Otto, W | 1 |
Häntzschel, H | 1 |
Willcox, RR | 2 |
Storck, H | 1 |
Sonninen, V | 1 |
Riekkinen, P | 1 |
Rinne, UK | 1 |
Maciejewska-Udziela, B | 1 |
Nowakowski, H | 1 |
Towpik, J | 1 |
Bernhardt, E | 1 |
Brylak, K | 1 |
Stapiński, A | 1 |
Mayr, E | 1 |
Smithurst, BA | 1 |
Gottesbüren, H | 1 |
Strohmeyer, G | 1 |
Kelley, WN | 1 |
Wyngaarden, JB | 1 |
Panduro, J | 1 |
Klotz, H | 1 |
Prohaska, E | 1 |
Salmhofer, H | 1 |
Schmid, L | 1 |
Cobbold, RJ | 1 |
Spitzer, RJ | 1 |
Morrison, GD | 1 |
Straus, B | 1 |
Delcourt, A | 1 |
Wettendorff, P | 1 |
Askenasi, P | 1 |
Lapidus, PW | 1 |
Guidotti, FP | 1 |
5 reviews available for probenecid and Acute Disease
Article | Year |
---|---|
Hyperuricemia and gout. Classification, complications and management.
Topics: Acute Disease; Allopurinol; Arthritis; Aspirin; Colchicine; Coronary Disease; Diuretics; Gout; Human | 1979 |
Hyperuricemia and gout.
Topics: Acute Disease; Adult; Allopurinol; Anti-Inflammatory Agents; Arthritis; Arthrography; Calcinosis; Ch | 1986 |
[Antarthritics. 41].
Topics: Acute Disease; Allopurinol; Antineoplastic Agents; Benzofurans; Colchicine; Female; Gout; Humans; Ph | 1969 |
[What is certain in gout therapy?].
Topics: Acute Disease; Allopurinol; Chronic Disease; Colchicine; Gout; Humans; Hydrogen-Ion Concentration; K | 1971 |
Drug treatment of gout.
Topics: Acute Disease; Allopurinol; Arthritis; Colchicine; Gout; Humans; Orotic Acid; Probenecid; Structure- | 1971 |
11 trials available for probenecid and Acute Disease
Article | Year |
---|---|
Open randomized study of pyrimethamine-sulphadoxine vs. pyrimethamine-sulphadoxine plus probenecid for the treatment of uncomplicated Plasmodium falciparum malaria in children.
Topics: Acute Disease; Antimalarials; Child; Child, Preschool; Drug Combinations; Drug Interactions; Drug Re | 2004 |
Treatment of acute gonococcal urethritis in men with simultaneous infection with Chlamydia trachomatis.
Topics: Acute Disease; Ampicillin; Anti-Infective Agents, Urinary; Chlamydia Infections; Chlamydia trachomat | 1984 |
[Treatment of gonorrhea in Santiago de Chile].
Topics: Acute Disease; Anti-Bacterial Agents; Chile; Clinical Trials as Topic; Drug Therapy, Combination; Fe | 1984 |
'One-visit' therapy for pelvic inflammatory disease.
Topics: Acute Disease; Blood Sedimentation; Drug Therapy, Combination; Escherichia coli; Female; Fever; Huma | 1980 |
Comparative trial to evaluate the efficacy and tolerability of cefuroxime 250mg with probenecid 250mg with cefuroxime 500mg in the management of community acquired pneumonia, acute bronchitis and acute exacerbation of chronic bronchitis.
Topics: Acute Disease; Adult; Bronchitis; Cefuroxime; Cephalosporins; Community-Acquired Infections; Drug Th | 2000 |
The efficacy of cefuroxime for the treatment of acute gonorrhoea in men.
Topics: Acute Disease; Cephalosporins; Drug Administration Schedule; Drug Therapy, Combination; Furans; Gono | 1978 |
Comparison of fleroxacin and penicillin G plus probenecid in the treatment of acute uncomplicated gonococcal infections.
Topics: Acute Disease; Adolescent; Adult; Drug Therapy, Combination; Fleroxacin; Gonorrhea; Humans; Male; Mi | 1992 |
A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis.
Topics: Acute Disease; Adult; Ambulatory Care; Cefoxitin; Chi-Square Distribution; Chlamydia Infections; Chl | 1991 |
[Combination of pivampicillin and probenecid in the treatment of acute gonorrhea in the male. Experimental and clinical studies].
Topics: Acute Disease; Ampicillin; Clinical Trials as Topic; Drug Therapy, Combination; Gonorrhea; Humans; M | 1974 |
Treatment of acute gonococcal urethritis with three drug regimes in 768 males, Brisbane, Queensland, 1967-69.
Topics: Acute Disease; Adolescent; Adult; Australia; Clinical Trials as Topic; Gonorrhea; Humans; Male; Marr | 1970 |
One-session treatment of gonorrhoea in males with procaine penicillin plus probenecid.
Topics: Acute Disease; Drug Synergism; Gonorrhea; Humans; Male; Penicillin G Procaine; Probenecid | 1970 |
44 other studies available for probenecid and Acute Disease
Article | Year |
---|---|
[Enhancement of penicillinemia as obtained with dipropylsulfamylbenzoic acid (probenecid, benamid) in three patients treated by a penicillin-streptomycin combination for malignant endocarditis].
Topics: Acute Disease; Endocarditis, Bacterial; Humans; Penicillins; Polycythemia Vera; Probenecid; Stomach; | 1957 |
Comparative effects of pyrimethamine-sulfadoxine, with and without probenecid, on Plasmodium falciparum gametocytes in children with acute, uncomplicated malaria.
Topics: Acute Disease; Animals; Antimalarials; Child; Drug Combinations; Drug Therapy, Combination; Endemic | 2004 |
A comparative trial of cefuroxime axetil and ampicillin plus probenecid in the treatment of acute gonococcal infection.
Topics: Acute Disease; Ampicillin; Anti-Bacterial Agents; Cefuroxime; Clinical Trials as Topic; Drug Therapy | 1989 |
Gout: joint pain and more.
Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Gout; Gout Suppressa | 2007 |
Urethritis and epididymitis.
Topics: Acute Disease; Administration, Oral; Anti-Bacterial Agents; Drug Therapy, Combination; Epididymitis; | 1983 |
Acute urinary retention secondary to severe gonococcal balanoblennorrhea.
Topics: Acute Disease; Ampicillin; Child; Child, Preschool; Drug Therapy, Combination; Gonorrhea; Humans; In | 1981 |
Diagnostic and therapeutic aids in gout and hyperuricemia.
Topics: Acute Disease; Allopurinol; Arthritis, Rheumatoid; Colchicine; Diagnosis, Differential; Gout; Humans | 1981 |
Probenecid protects against In vivo acetaminophen-induced nephrotoxicity in male Wistar rats.
Topics: Acetaminophen; Acute Disease; Animals; Biological Transport; Creatinine; Diuresis; Glomerular Filtra | 1998 |
Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acute Disease; Animals; Axons; Brain; Cell Death; Chro | 2001 |
Evaluation of the clinical relevance of the expression and function of P-glycoprotein, multidrug resistance protein and lung resistance protein in patients with primary acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; | 2002 |
[Hyperuricemia and gout--treatment].
Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Colchicine; Drug | 2002 |
Gonorrhea: recommended treatment schedules.
Topics: Acute Disease; Ampicillin; Anti-Bacterial Agents; Child; Female; Gonorrhea; Humans; Infant, Newborn; | 1975 |
Gonorrhea: recommended treatment schedules--1974. Part I: Uncomplicated gonococcal infections in men and women; uncomplicated gonorrhea in pregnant patients; and acute salpingitis.
Topics: Acute Disease; Ampicillin; Coitus; Female; Gonorrhea; Humans; Male; Penicillin G Procaine; Pharyngea | 1975 |
[Treatment results in acute gonorrhea using spectinomycin. Comparative study using aqueous penicillin combined with probenecid].
Topics: Acute Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Gonorrhea; Humans; Male; Penici | 1977 |
Evaluation of tetracycline or penicillin and ampicillin for treatment of acute pelvic inflammatory disease.
Topics: Acute Disease; Adult; Ampicillin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Inject | 1977 |
Recommended treatment schedules for gonorrhea--1979.
Topics: Acute Disease; Adult; Amoxicillin; Ampicillin; Child; Drug Administration Schedule; Epididymitis; Fe | 1979 |
Treating gout: successful methods of prevention and control.
Topics: Acute Disease; Allopurinol; Colchicine; Gout; Humans; Probenecid | 1978 |
Treatment of gonorrhoea with a combination of probenecid and procaine penicillin in Rwanda.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Africa, Central; Drug Evaluation; Drug Thera | 1976 |
Treatment of acute gonorrhoea with ampicillin and probenecid in Bangkok.
Topics: Acute Disease; Adolescent; Adult; Ampicillin; Drug Therapy, Combination; Female; Gonorrhea; Humans; | 1977 |
Hyperamylasemia associated with gonococcal salpingitis and perihepatitis.
Topics: Acute Disease; Adult; Ampicillin; Amylases; Creatinine; Diagnosis, Differential; Female; Gonorrhea; | 1976 |
CSF acid monoamine metabolities as a possible reflection of central MAO activity in chronic schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Bipolar Disorder; Chronic Disease; Female; Homovanillic Acid; Huma | 1976 |
Cerebrospinal fluid amine metabolites in acute schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Amines; Bipolar Disorder; Dopamine; Homovanillic Acid; Humans; Hyd | 1975 |
[Uncomplicated acute male and female gonorrhea: treatment with a single oral dose of epicillin-probenecid].
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Ampicillin; Ampicillin Resistance; Drug Comb | 1989 |
[Treatment of male non-complicated acute gonorrhea with a single dose of a combination of sodium penicillin and clemizolpenicillin, plus probenecid].
Topics: Acute Disease; Adolescent; Adult; Benzimidazoles; Drug Combinations; Drug Therapy, Combination; Gono | 1987 |
[Amoxicillin in the treatment of gonorrhea].
Topics: Acute Disease; Amoxicillin; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Probenecid | 1988 |
Possible cardioprotective effects of allopurinol.
Topics: Acute Disease; Aged; Allopurinol; Cohort Studies; Colchicine; Drug Combinations; Female; Gout; Healt | 1988 |
Three regimens of procaine penicillin G, Augmentin, and probenecid compared for treating acute gonorrhoea in men.
Topics: Acute Disease; Administration, Oral; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combinati | 1986 |
Pivampicillin combined with probenecid in the treatment of acute uncomplicated gonorrhoea.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Ampicillin; Drug Therapy, Combination; Femal | 1973 |
Treatment of uncomplicated gonorrhea in women with a single dose of amoxicillin.
Topics: Acute Disease; Administration, Oral; Adult; Amines; Ampicillin; Cervix Uteri; Drug Combinations; Fem | 1974 |
Oral amoxicillin in acute uncomplicated gonorrhea.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Amines; Drug Evaluation; Female; Follow-Up S | 1974 |
Treatment of acute gonococcal urethritis in Bangkok, Thailand.
Topics: Acute Disease; Ampicillin; Drug Therapy, Combination; Gonorrhea; Humans; Injections, Intramuscular; | 1974 |
Amoxicillin in the treatment of gonorrhea.
Topics: Acute Disease; Administration, Oral; Amines; Cervix Uteri; Drug Combinations; Drug Eruptions; Female | 1974 |
Recent developments in the therapy of gout.
Topics: Acute Disease; Adrenocorticotropic Hormone; Allopurinol; Analgesics; Colchicine; Gout; Humans; Oxyph | 1968 |
[Modern therapy of gout].
Topics: Acute Disease; Chronic Disease; Colchicine; Diet, Reducing; Female; Gout; Humans; Indomethacin; Kidn | 1972 |
Amoxycillin in the treatment of gonorrhoea.
Topics: Acute Disease; Amines; Ampicillin; Benzyl Compounds; Cephalosporins; Gonorrhea; Humans; Male; Penici | 1972 |
[New data on the therapy of gonorrhea].
Topics: Acute Disease; Ampicillin; Anti-Bacterial Agents; Doxycycline; Gonorrhea; Humans; Penicillins; Probe | 1973 |
Acid monoamine metabolites in cerebrospinal fluid in multiple sclerosis.
Topics: Acute Disease; Adult; Brain; Chronic Disease; Demyelinating Diseases; Female; Homovanillic Acid; Hum | 1973 |
[Results of 1-day treatment of acute gonorrhea with benemide and penicillin].
Topics: Acute Disease; Female; Gonorrhea; Humans; Male; Methods; Penicillins; Probenecid; Time Factors | 1973 |
[Various methods of treatment of gonorrhea with penicillin in men based on studies of the Institute of Venerology].
Topics: Acute Disease; Evaluation Studies as Topic; Gonorrhea; Humans; Male; Methods; Penicillin G Procaine; | 1973 |
Treatment of acute gonorrhoea with a single oral dose of rifampicin.
Topics: Acute Disease; Administration, Oral; Female; Gonorrhea; Humans; Male; Penicillins; Probenecid; Rifam | 1971 |
[Gout from the view of a special hospital for rheumatic patients].
Topics: Acute Disease; Adolescent; Adult; Aged; Austria; Child; Cholesterol; Colchicine; Colic; Diabetes Com | 1971 |
Problems and progress in geriatrics.
Topics: Acute Disease; Aged; Aging; Calcitonin; Cardiovascular Diseases; Chronic Disease; Diabetic Coma; Dia | 1968 |
[Amylase in urine and acute pancreatitis. Experimental study in the dog].
Topics: Acute Disease; Amylases; Animals; Dogs; Pancreatitis; Probenecid | 1968 |
Gout in orthopaedic practice: review of 232 cases.
Topics: Acute Disease; Adolescent; Aged; Bone Diseases; Chlorothiazide; Colchicine; Diagnosis, Differential; | 1963 |