probenecid has been researched along with Abdominal Migraine in 3 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although kynurenic acid does not cross the BBB, its precursor, kynurenine, if combined with probenecid, crosses it readily." | 1.34 | Kynurenine in combination with probenecid mitigates the stimulation-induced increase of c-fos immunoreactivity of the rat caudal trigeminal nucleus in an experimental migraine model. ( Chadaide, Z; Fenyo, R; Knyihár-Csillik, E; Krisztin-Péva, B; Mihály, A; Németh, H; Toldi, J; Vécsei, L, 2007) |
| " The present investigation tested the hypothesis of whether kynurenine in combination with systemically administered probenecid protects second-order trigeminal neurons against stimulation arriving via central processes of trigeminal ganglion cells." | 1.34 | Prevention of electrical stimulation-induced increase of c-fos immunoreaction in the caudal trigeminal nucleus by kynurenine combined with probenecid. ( Chadaide, Z; Fenyo, R; Knyihár-Csillik, E; Krisztin-Péva, B; Németh, H; Toldi, J; Vécsei, L, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vámos, E | 1 |
| Knyihár-Csillik, E | 2 |
| Toldi, J | 2 |
| Mihály, A | 1 |
| Krisztin-Péva, B | 2 |
| Chadaide, Z | 2 |
| Németh, H | 2 |
| Fenyo, R | 2 |
| Vécsei, L | 2 |
3 other studies available for probenecid and Abdominal Migraine
| Article | Year |
|---|---|
Protective compounds in animal models of trigeminal activation and neurodegeneration.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combi | 2012 |
Kynurenine in combination with probenecid mitigates the stimulation-induced increase of c-fos immunoreactivity of the rat caudal trigeminal nucleus in an experimental migraine model.
Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Genes, fos; Immunohistochemistry; Kynure | 2007 |
Prevention of electrical stimulation-induced increase of c-fos immunoreaction in the caudal trigeminal nucleus by kynurenine combined with probenecid.
Topics: Adjuvants, Pharmaceutic; Afferent Pathways; Analgesics; Animals; Blood-Brain Barrier; Disease Models | 2007 |