proadifen has been researched along with Paralysis in 6 studies
Proadifen: An inhibitor of drug metabolism and CYTOCHROME P-450 ENZYME SYSTEM activity.
Paralysis: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pretreatment with piperine prolonged hexobarbital sleeping time and zoxazolamine paralysis time in mice at half the dose of SKF-525A." | 3.67 | Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism. ( Atal, CK; Dubey, RK; Singh, J, 1985) |
| " This compound prolonged hexobarbitone sleeping times and zoxazolamine paralysis times in mice." | 3.66 | Metabolite involvement in bromocriptine-induced circling behaviour in rodents. ( Jenner, P; Marsden, CD; Reavill, C, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reavill, C | 1 |
| Jenner, P | 1 |
| Marsden, CD | 1 |
| Monnet, FP | 1 |
| Debonnel, G | 1 |
| de Montigny, C | 1 |
| Atal, CK | 1 |
| Dubey, RK | 1 |
| Singh, J | 1 |
| Szabo, S | 1 |
| Selye, H | 1 |
| Kourounakis, P | 1 |
| Taché, Y | 1 |
| Murphy, JP | 1 |
| Van Stee, EW | 1 |
| Back, KC | 1 |
| Gerber, N | 1 |
| Arnold, K | 1 |
6 other studies available for proadifen and Paralysis
| Article | Year |
|---|---|
Metabolite involvement in bromocriptine-induced circling behaviour in rodents.
Topics: Amphetamine; Animals; Apomorphine; Biotransformation; Bromocriptine; Desipramine; Female; Hydroxydop | 1980 |
The cytochromes P-450 are not involved in the modulation of the N-methyl-D-aspartate response by sigma ligands in the rat CA3 dorsal hippocampus.
Topics: Animals; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophysiology; Guanid | 1993 |
Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism.
Topics: Alkaloids; Animals; Aryl Hydrocarbon Hydroxylases; Benzodioxoles; Biological Availability; Dose-Resp | 1985 |
Comparative studies on the effect of adrenocorticotrophic hormone (ACTH) and pregnenolone-16alpha-carbonitrile (PCN) upon drug response and distribution in rats.
Topics: Adrenocorticotropic Hormone; Animals; Biotransformation; Brain Chemistry; Dose-Response Relationship | 1974 |
Effect of dibromotetrafluoroethane inhalation on hepatic drug metabolism in mice.
Topics: Animals; Chlorofluorocarbons, Methane; Drug Interactions; Hexobarbital; Hydrocarbons, Halogenated; L | 1973 |
Studies on the metabolism of diphenylhydantoin in mice.
Topics: Animals; Cycloheximide; Cytochromes; Hexobarbital; Hydroxyzine; Kinetics; Liver; Male; Mice; Microso | 1969 |