proadifen has been researched along with Leukemia, Lymphoid in 1 studies
Proadifen: An inhibitor of drug metabolism and CYTOCHROME P-450 ENZYME SYSTEM activity.
Leukemia, Lymphoid: Leukemia associated with HYPERPLASIA of the lymphoid tissues and increased numbers of circulating malignant LYMPHOCYTES and lymphoblasts.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response curves with and without phenobarbital pretreatment showed a constant 90% (1-log) reduction in the toxicity of cyclophosphamide to leukemic colony-forming units, whereas enzyme induction had no effect on the toxicity of the drug to normal bone marrow colony-forming units." | 1.26 | The effect of phenobarbital on cyclophosphamide antitumor activity. ( Alberts, DS; van Daalen Wetters, T, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alberts, DS | 1 |
| van Daalen Wetters, T | 1 |
1 other study available for proadifen and Leukemia, Lymphoid
| Article | Year |
|---|---|
The effect of phenobarbital on cyclophosphamide antitumor activity.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Dose-Response Relationship, Drug; Drug In | 1976 |