proadifen has been researched along with Inflammation in 5 studies
Proadifen: An inhibitor of drug metabolism and CYTOCHROME P-450 ENZYME SYSTEM activity.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A decrease of the hepatic intrinsic clearance could contribute to the increase of the plasma concentrations of alpha 1-acid glycoprotein-bound drugs such as propranolol in animals and humans with inflammation." | 7.67 | Effect of inflammation on the metabolism of antipyrine, lidocaine and propranolol in isolated rat hepatocytes. ( Belpaire, FM; Bogaert, MG; Chindavijak, B, 1988) |
| "A decrease of the hepatic intrinsic clearance could contribute to the increase of the plasma concentrations of alpha 1-acid glycoprotein-bound drugs such as propranolol in animals and humans with inflammation." | 3.67 | Effect of inflammation on the metabolism of antipyrine, lidocaine and propranolol in isolated rat hepatocytes. ( Belpaire, FM; Bogaert, MG; Chindavijak, B, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, M | 1 |
| Ray, SM | 1 |
| Iwai, T | 1 |
| Iinuma, Y | 1 |
| Kodani, R | 1 |
| Oka, J | 1 |
| Chindavijak, B | 2 |
| Belpaire, FM | 2 |
| Bogaert, MG | 2 |
| Prabhu, VG | 1 |
| Rise, NL | 1 |
| Oester, YT | 1 |
5 other studies available for proadifen and Inflammation
| Article | Year |
|---|---|
Synthesis and biological evaluation of amide derivatives of (5,6-dimethoxy-2,3-dihydro-1H-inden-1-yl)acetic acid as anti-inflammatory agents with reduced gastrointestinal ulcerogenecity.
Topics: Acetates; Amides; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthri | 2008 |
Neuromedin U inhibits inflammation-mediated memory impairment and neuronal cell-death in rodents.
Topics: Animals; Anti-Inflammatory Agents; Brain-Derived Neurotrophic Factor; Cell Death; Cells, Cultured; D | 2008 |
Effect of inflammation and proadifen on the disposition of antipyrine, lignocaine and propranolol in rat isolated perfused liver.
Topics: Animals; Antipyrine; In Vitro Techniques; Inflammation; Lidocaine; Liver; Male; Proadifen; Propranol | 1987 |
Effect of inflammation on the metabolism of antipyrine, lidocaine and propranolol in isolated rat hepatocytes.
Topics: Animals; Antipyrine; Inflammation; Lidocaine; Liver; Male; Proadifen; Propranolol; Rats; Rats, Inbre | 1988 |
The effect of experimental local inflammation on the action of barbiturates in rat.
Topics: Animals; Barbiturates; Carbon Tetrachloride; Carrageenan; Charcoal; Chlordan; Enzyme Induction; Goss | 1972 |