proadifen has been researched along with Hypoxia in 7 studies
Proadifen: An inhibitor of drug metabolism and CYTOCHROME P-450 ENZYME SYSTEM activity.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effects of cytochrome P-450 inhibitor [2-dimethylaminoethyl-2,2-diphenyl-n-pentanoate (SKF-525A) and metyrapone] on the response of rabbit aortic rings to GTN was determined by recording cumulative GTN dose-response curves in the presence of either or both inhibitors." | 1.29 | Lack of evidence for the involvement of cytochrome P-450 or other hemoproteins in metabolic activation of glyceryl trinitrate in rabbit aorta. ( Brien, JF; Liu, Z; Marks, GS; McLaughlin, BE; Nakatsu, K, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Earley, S | 1 |
| Pastuszyn, A | 1 |
| Walker, BR | 1 |
| Paky, A | 1 |
| Michael, JR | 1 |
| Burke-Wolin, TM | 1 |
| Wolin, MS | 1 |
| Gurtner, GH | 1 |
| Liu, Z | 1 |
| Brien, JF | 1 |
| Marks, GS | 1 |
| McLaughlin, BE | 1 |
| Nakatsu, K | 1 |
| Sylvester, JT | 1 |
| McGowan, C | 1 |
| McMurtry, IF | 1 |
| Davidson, AB | 1 |
| Reeves, JT | 1 |
| Grover, RF | 1 |
| Boobis, AR | 1 |
| Powis, G | 1 |
| Roh, BL | 1 |
| Paulo, LG | 1 |
| Fisher, JW | 1 |
7 other studies available for proadifen and Hypoxia
| Article | Year |
|---|---|
Cytochrome p-450 epoxygenase products contribute to attenuated vasoconstriction after chronic hypoxia.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Calcium Chan | 2003 |
Endogenous production of superoxide by rabbit lungs: effects of hypoxia or metabolic inhibitors.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-d | 1993 |
Lack of evidence for the involvement of cytochrome P-450 or other hemoproteins in metabolic activation of glyceryl trinitrate in rabbit aorta.
Topics: Animals; Aorta; Biotransformation; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hemeproteins; Hy | 1993 |
The effects of agents that bind to cytochrome P-450 on hypoxic pulmonary vasoconstriction.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Extracorporeal Circulation; Hypoxia; Lung; | 1978 |
Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs.
Topics: Angiotensin II; Animals; Calcium; Hypoxia; Male; Meclofenamic Acid; Proadifen; Prostaglandins; Prost | 1976 |
The effects of catecholamines upon the metabolism of foreign compounds and upon the distribution of perfusate in the isolated liver of the rat.
Topics: Aniline Compounds; Animals; Bucladesine; Calcium; Catecholamines; Epinephrine; Half-Life; Hexobarbit | 1974 |
Metabolism of erythropoietin by isolated perfused livers of dogs treated with SKF 525-A.
Topics: Animals; Depression, Chemical; Dogs; Erythropoietin; Female; Hypoxia; Liver; Perfusion; Phenobarbita | 1972 |