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proadifen and Hypothermia

proadifen has been researched along with Hypothermia in 3 studies

Proadifen: An inhibitor of drug metabolism and CYTOCHROME P-450 ENZYME SYSTEM activity.

Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment of mice with phenobarbital, an inducer of oxidative drug metabolism, had no effect on the early hypothermic effect of a toxic dose of acetaminophen, while pretreatment with metyrapone, SKF-525A, or piperonyl butoxide (inhibitors of mixed-function oxidase) enhanced the hypothermia."7.66Acetaminophen-induced hypothermia in mice: evidence for a central action of the parent compound. ( Massey, TE; McElligott, TF; Racz, WJ; Walker, RM, 1982)
"Pretreatment of mice with phenobarbital, an inducer of oxidative drug metabolism, had no effect on the early hypothermic effect of a toxic dose of acetaminophen, while pretreatment with metyrapone, SKF-525A, or piperonyl butoxide (inhibitors of mixed-function oxidase) enhanced the hypothermia."3.66Acetaminophen-induced hypothermia in mice: evidence for a central action of the parent compound. ( Massey, TE; McElligott, TF; Racz, WJ; Walker, RM, 1982)
" Proadifen antagonized the action of IMI when investigated in reserpine hypothermia and ptosis and in the behavioral despair test."3.66Influence of proadifen, an inhibitor of the metabolism of drugs, on the action of imipramine and desipramine in rats. ( Daniel, W; Maj, J; Rogóz, Z; Skuza, G; Sowińska, H, 1981)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Massey, TE1
Walker, RM1
McElligott, TF1
Racz, WJ1
Maj, J1
Daniel, W1
Rogóz, Z1
Skuza, G1
Sowińska, H1
Matsuda, T1
Nakano, Y1
Kanda, T1
Iwata, H1
Baba, A1

Other Studies

3 other studies available for proadifen and Hypothermia

ArticleYear
Acetaminophen-induced hypothermia in mice: evidence for a central action of the parent compound.
    Toxicology, 1982, Volume: 25, Issue:2-3

    Topics: Acetaminophen; Animals; Hypothermia; Male; Mice; Phenobarbital; Piperonyl Butoxide; Proadifen; Time

1982
Influence of proadifen, an inhibitor of the metabolism of drugs, on the action of imipramine and desipramine in rats.
    Polish journal of pharmacology and pharmacy, 1981, Volume: 33, Issue:6

    Topics: Animals; Blepharoptosis; Desipramine; Hypothermia; Imipramine; Male; Motor Activity; Proadifen; Rats

1981
Gonadal hormones affect the hypothermia induced by serotonin1A (5-HT1A) receptor activation.
    Life sciences, 1991, Volume: 48, Issue:17

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Castration; Dose-Response Relatio

1991