proadifen has been researched along with Hypothermia in 3 studies
Proadifen: An inhibitor of drug metabolism and CYTOCHROME P-450 ENZYME SYSTEM activity.
Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.
Excerpt | Relevance | Reference |
---|---|---|
"Pretreatment of mice with phenobarbital, an inducer of oxidative drug metabolism, had no effect on the early hypothermic effect of a toxic dose of acetaminophen, while pretreatment with metyrapone, SKF-525A, or piperonyl butoxide (inhibitors of mixed-function oxidase) enhanced the hypothermia." | 7.66 | Acetaminophen-induced hypothermia in mice: evidence for a central action of the parent compound. ( Massey, TE; McElligott, TF; Racz, WJ; Walker, RM, 1982) |
"Pretreatment of mice with phenobarbital, an inducer of oxidative drug metabolism, had no effect on the early hypothermic effect of a toxic dose of acetaminophen, while pretreatment with metyrapone, SKF-525A, or piperonyl butoxide (inhibitors of mixed-function oxidase) enhanced the hypothermia." | 3.66 | Acetaminophen-induced hypothermia in mice: evidence for a central action of the parent compound. ( Massey, TE; McElligott, TF; Racz, WJ; Walker, RM, 1982) |
" Proadifen antagonized the action of IMI when investigated in reserpine hypothermia and ptosis and in the behavioral despair test." | 3.66 | Influence of proadifen, an inhibitor of the metabolism of drugs, on the action of imipramine and desipramine in rats. ( Daniel, W; Maj, J; Rogóz, Z; Skuza, G; Sowińska, H, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (66.67) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Massey, TE | 1 |
Walker, RM | 1 |
McElligott, TF | 1 |
Racz, WJ | 1 |
Maj, J | 1 |
Daniel, W | 1 |
Rogóz, Z | 1 |
Skuza, G | 1 |
Sowińska, H | 1 |
Matsuda, T | 1 |
Nakano, Y | 1 |
Kanda, T | 1 |
Iwata, H | 1 |
Baba, A | 1 |
3 other studies available for proadifen and Hypothermia
Article | Year |
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Acetaminophen-induced hypothermia in mice: evidence for a central action of the parent compound.
Topics: Acetaminophen; Animals; Hypothermia; Male; Mice; Phenobarbital; Piperonyl Butoxide; Proadifen; Time | 1982 |
Influence of proadifen, an inhibitor of the metabolism of drugs, on the action of imipramine and desipramine in rats.
Topics: Animals; Blepharoptosis; Desipramine; Hypothermia; Imipramine; Male; Motor Activity; Proadifen; Rats | 1981 |
Gonadal hormones affect the hypothermia induced by serotonin1A (5-HT1A) receptor activation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Castration; Dose-Response Relatio | 1991 |