proadifen has been researched along with Disease Models, Animal in 8 studies
Proadifen: An inhibitor of drug metabolism and CYTOCHROME P-450 ENZYME SYSTEM activity.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gentiopicroside (GPS) is a secoiridoid glucoside isolated from the ethanol extract of Gentianae Radix with a content of 13%, which has been used for centuries in Chinese as a digestive aid." | 1.38 | Isolation of gentiopicroside from Gentianae Radix and its pharmacokinetics on liver ischemia/reperfusion rats. ( Chang-Liao, WL; Chien, CF; Lin, LC; Tsai, TH, 2012) |
| "Diethylnitrosamine metabolism was measured based on nitrite formation and liver histology using GGT histochemistry." | 1.38 | Cancer prevention mediated by caffeic acid phenethyl ester involves cyp2b1/2 modulation in hepatocarcinogenesis. ( Beltrán-Ramírez, O; Pérez, RM; Sierra-Santoyo, A; Villa-Treviño, S, 2012) |
| "Medroxyprogesterone acetate (MPA) is a drug commonly used in endocrine therapy for advanced breast cancer, although it is known to cause thrombosis as a serious side effect." | 1.32 | Metabolism of medroxyprogesterone acetate (MPA) via CYP enzymes in vitro and effect of MPA on bleeding time in female rats in dependence on CYP activity in vivo. ( Chiba, K; Hosokawa, M; Kobayashi, K; Mimura, N; Nakamura, Y; Shimada, N, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Chang-Liao, WL | 1 |
| Chien, CF | 1 |
| Lin, LC | 1 |
| Tsai, TH | 1 |
| Beltrán-Ramírez, O | 1 |
| Pérez, RM | 1 |
| Sierra-Santoyo, A | 1 |
| Villa-Treviño, S | 1 |
| Mimura, N | 1 |
| Kobayashi, K | 1 |
| Nakamura, Y | 1 |
| Shimada, N | 1 |
| Hosokawa, M | 2 |
| Chiba, K | 1 |
| Kamata, K | 1 |
| Matsumoto, T | 1 |
| Kobayashi, T | 1 |
| Tesfamariam, B | 1 |
| Brown, ML | 1 |
| Cohen, RA | 1 |
| Lunam, CA | 1 |
| Cousins, MJ | 1 |
| Hall, PD | 1 |
8 other studies available for proadifen and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Isolation of gentiopicroside from Gentianae Radix and its pharmacokinetics on liver ischemia/reperfusion rats.
Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Biotransformation; Chromat | 2012 |
Cancer prevention mediated by caffeic acid phenethyl ester involves cyp2b1/2 modulation in hepatocarcinogenesis.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Caffeic Acids; Carcinogenicity Tests; Cytochr | 2012 |
Metabolism of medroxyprogesterone acetate (MPA) via CYP enzymes in vitro and effect of MPA on bleeding time in female rats in dependence on CYP activity in vivo.
Topics: Animals; Bleeding Time; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Disease Models, Anim | 2003 |
Altered arachidonic acid-mediated responses in the perfused kidney of the streptozotocin-induced diabetic rat.
Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Diabetes M | 2006 |
15-Hydroxyeicosatetraenoic acid and diabetic endothelial dysfunction in rabbit aorta.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Bridged Bicyclo Compounds, Heterocyclic; Cytochrome P-450 | 1995 |
Guinea-pig model of halothane-associated hepatotoxicity in the absence of enzyme induction and hypoxia.
Topics: Animals; Biotransformation; Blood Gas Analysis; Chemical and Drug Induced Liver Injury; Disease Mode | 1985 |