proadifen has been researched along with Cystic Fibrosis in 1 studies
Proadifen: An inhibitor of drug metabolism and CYTOCHROME P-450 ENZYME SYSTEM activity.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketoconazole treatment effectively reversed the cystic fibrosis defect in these cultured cells." | 5.29 | Ketoconazole activates Cl- conductance and blocks Cl- and fluid absorption by cultured cystic fibrosis (CFPAC-1) cells. ( Kersting, D; Kersting, U; Spring, KR, 1993) |
| "Ketoconazole treatment effectively reversed the cystic fibrosis defect in these cultured cells." | 1.29 | Ketoconazole activates Cl- conductance and blocks Cl- and fluid absorption by cultured cystic fibrosis (CFPAC-1) cells. ( Kersting, D; Kersting, U; Spring, KR, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kersting, U | 1 |
| Kersting, D | 1 |
| Spring, KR | 1 |
1 other study available for proadifen and Cystic Fibrosis
| Article | Year |
|---|---|
Ketoconazole activates Cl- conductance and blocks Cl- and fluid absorption by cultured cystic fibrosis (CFPAC-1) cells.
Topics: Absorption; Cell Line; Cell Membrane; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fi | 1993 |