proadifen has been researched along with Body Weight in 23 studies
Proadifen: An inhibitor of drug metabolism and CYTOCHROME P-450 ENZYME SYSTEM activity.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with phenobarbital, piperonyl butoxide (2 h), SKF 525-A, or small multiple doses of OOS protected against the OOS-induced elevated level of bronchopulmonary lavage LDH, and the other signs of delayed toxicity including morphological alteration of Clara cells." | 1.27 | Effect of drug metabolism inducer and inhibitor on O,O,S-trimethyl phosphorothioate-induced delayed toxicity in rats. ( Fukuto, TR; Gandy, J; Hasegawa, L; Imamura, T, 1983) |
| "To study the effects of SKF-525A, an inhibitor of cytochrome P-450, and of sodium phenobarbital (PB), a drug-metabolizing enzyme inducer, on the teratogenicity of thiabendazole (TBZ), pregnant mice were given ip either a single dose of 40 mg SKF-525A/kg 1 hr before oral dosing with 250 or 500 mg TBZ/kg or a dose of 75 mg PB/kg/day on three consecutive days before oral administration of a dose of 500 or 1000 mg TBZ/kg." | 1.27 | Effects of pretreatment with SKF-525A or sodium phenobarbital on thiabendazole-induced teratogenicity in ICR mice. ( Imamichi, T; Ogata, A; Sasaki, M; Suzuki, K; Yoneyama, M, 1987) |
| "The LD50 of phencyclidine (PCP, 234 mumol/kg, i." | 1.26 | The role of hepatic microsomal enzymes in the modulation of phencyclidine-induced toxicity. ( Berg, IE; Chaturvedi, AK; Rao, NG, 1981) |
| "Phenobarbital treatment antagonized THC-induced reduction of fetal body weight, but did not reduce resorption rate." | 1.26 | Alteration of delta 9-tetrahydrocannabinol-induced teratogenicity by stimulation and inhibition of its metabolism. ( Harbison, RD; Lubin, DJ; Mantilla-Plata, B, 1977) |
| "6 Animals withdrawn following chronic administration of a number of drugs, barbitone, barbitone/bemegride mixture, Mandrax (methaqualone: diphenhydramine; 10: 1), chlordiazepoxide, nitrazepam, chlorpromazine or ethanol, exhibited a significant tolerance to intracerebroventricularly administered pentobarbitone." | 1.25 | A study of the factors affecting the sleeping time following intracerebroventricular administration of pentobarbitone sodium: effect of prior administration of centrally active drugs. ( Stevenson, IH; Turnbull, MJ, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (91.30) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huffman, DH | 1 |
| Azarnoff, DL | 1 |
| Imamura, T | 1 |
| Hasegawa, L | 1 |
| Gandy, J | 1 |
| Fukuto, TR | 1 |
| Masten, LW | 1 |
| Peterson, GR | 1 |
| Burkhalter, A | 1 |
| Way, EL | 1 |
| Chaturvedi, AK | 1 |
| Rao, NG | 1 |
| Berg, IE | 1 |
| Kaneko, K | 1 |
| Uchida, K | 1 |
| Kobayashi, T | 1 |
| Miura, K | 1 |
| Tanokura, K | 1 |
| Hoshino, K | 1 |
| Kato, I | 1 |
| Onoue, M | 1 |
| Yokokura, T | 1 |
| Allen, JR | 1 |
| Harbison, RD | 2 |
| Mantilla-Plata, B | 1 |
| Lubin, DJ | 1 |
| Cooper, DY | 1 |
| Schleyer, H | 1 |
| Thomas, JH | 1 |
| Vars, HM | 1 |
| Rosenthal, O | 1 |
| Preache, MM | 1 |
| Gibson, JE | 2 |
| Dahlström-King, L | 1 |
| Couture, J | 1 |
| Plaa, GL | 1 |
| Ogata, A | 1 |
| Yoneyama, M | 1 |
| Sasaki, M | 1 |
| Suzuki, K | 1 |
| Imamichi, T | 1 |
| Stevenson, IH | 1 |
| Turnbull, MJ | 1 |
| Posner, HS | 1 |
| Graves, A | 1 |
| King, CT | 1 |
| Wilk, A | 1 |
| Khanna, JM | 1 |
| Kalant, H | 1 |
| Schenkman, JB | 1 |
| Wilson, BJ | 1 |
| Cinti, DL | 1 |
| Bus, JS | 1 |
| Short, RD | 1 |
| Fiserova-Bergerova, V | 1 |
| Miranda, CL | 1 |
| Webb, RE | 1 |
| Bond, EJ | 1 |
| De Matteis, F | 1 |
| Becker, BA | 1 |
| Yamamoto, RS | 1 |
| Weisburger, JH | 1 |
| Weisburger, EK | 1 |
| Huidobro, F | 1 |
| Huidobro, JP | 1 |
| Larraín, G | 1 |
| Jondorf, WR | 1 |
| Simon, DC | 1 |
| Avnimelech, M | 1 |
1 review available for proadifen and Body Weight
| Article | Year |
|---|---|
Response of the nonhuman primate to polychlorinated biphenyl exposure.
Topics: Animals; Blood; Body Weight; Dose-Response Relationship, Drug; Drug Synergism; Feces; Female; Hair; | 1975 |
22 other studies available for proadifen and Body Weight
| Article | Year |
|---|---|
The effect of hypocholesterolemic drugs on adrenal corticosteroid secretion.
Topics: Adrenal Glands; Animals; Anticholesteremic Agents; Body Weight; Butyrates; Cholesterol; Corticostero | 1967 |
Effect of drug metabolism inducer and inhibitor on O,O,S-trimethyl phosphorothioate-induced delayed toxicity in rats.
Topics: Animals; Body Weight; L-Lactate Dehydrogenase; Lethal Dose 50; Lung; Male; Organothiophosphates; Org | 1983 |
Tolerance to methadone lethality and microsomal enzyme induction in mice tolerant to and dependent on morphine.
Topics: Animals; Body Weight; Drug Tolerance; Enzyme Induction; Humans; Inactivation, Metabolic; Lethal Dose | 1980 |
The role of hepatic microsomal enzymes in the modulation of phencyclidine-induced toxicity.
Topics: Animals; Body Weight; Cysteine; Eating; Lethal Dose 50; Liver; Male; Maleates; Methylcholanthrene; M | 1981 |
Sex-dependent toxicity of a novel acyl-CoA:cholesterol acyltransferase inhibitor, YIC-C8-434, in relation to sex-specific forms of cytochrome P450 in rats.
Topics: Administration, Oral; Animals; Body Weight; Cinnamates; Cytochrome P-450 Enzyme System; Eating; Enzy | 2001 |
Alteration of delta 9-tetrahydrocannabinol-induced teratogenicity by stimulation and inhibition of its metabolism.
Topics: Amniotic Fluid; Animals; Body Weight; Cleft Palate; Dronabinol; Drug Interactions; Female; Fetal Dea | 1977 |
Comparison of the induction course, biophysical chemical interactions and photochemical action spectra of phenobarbital and 3-methylcholanthrene induce hepatic microsomal P-450.
Topics: Aniline Compounds; Animals; Biotransformation; Body Weight; Carbon Monoxide; Codeine; Cytochrome P-4 | 1975 |
Effect of food deprivation, phenobarbital, and SKF-525A on teratogenicity induced by 2-sec-butyl-4,6-dinitrophenol (dinoseb) and on disposition of [14C]dinoseb in mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Water; Body Weight; Bone and Bones; Dinitrophenols; Femal | 1975 |
Influence of agents affecting monooxygenase activity on taurolithocholic acid-induced cholestasis.
Topics: Animals; Bile; Body Weight; Chlordecone; Cholestasis; Cobalt; Cytochrome P-450 Enzyme Inhibitors; Cy | 1992 |
Effects of pretreatment with SKF-525A or sodium phenobarbital on thiabendazole-induced teratogenicity in ICR mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Bone and Bones; Female; Fetal Resorption; Male; M | 1987 |
A study of the factors affecting the sleeping time following intracerebroventricular administration of pentobarbitone sodium: effect of prior administration of centrally active drugs.
Topics: Aging; Amphetamine; Animals; Anti-Anxiety Agents; Barbiturates; Body Weight; Carbon Radioisotopes; C | 1974 |
Experimental alteration of the metabolism of chlorcyclizine and the incidence of cleft palate in rats.
Topics: Abnormalities, Drug-Induced; Adrenal Glands; Animals; Body Weight; Brain Chemistry; Carbon Isotopes; | 1967 |
Effect of inhibitors and inducers of drug metabolism on ethanol metabolism in vivo.
Topics: Animals; Body Weight; Ethanol; Female; Histamine H1 Antagonists; Male; Mathematics; Metabolism; Mice | 1970 |
Dimethylaminoethyl 2,2-diphenylvalerate HCl (SKF 525-A)--in vivo and in vitro effects of metabolism by rat liver microsomes--formation of an oxygenated complex.
Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Body Weight; Cytochrome P-450 Enzyme Sys | 1972 |
Effect of phenobarbital and SKF 525A on the toxicity, elimination and metabolism of cyclophosphamide in newborn mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Carbon Isotopes; Cyclophosphamide; Drug Synergism | 1973 |
Changes of fluoride content in bone: an index of drug defluorination in vivo.
Topics: Anesthetics; Animals; Biotransformation; Body Weight; Bone and Bones; Chlorine; Drug Interactions; E | 1973 |
Effects of dietary protein quality on drug metabolism in the rat.
Topics: Anesthesia; Aniline Compounds; Animals; Body Weight; Caseins; Cytochrome P-450 Enzyme System; Dealky | 1973 |
Biochemical changes in rat liver after administration of carbon disulphide, with particular reference to microsomal changes.
Topics: Adjuvants, Anesthesia; Aniline Compounds; Animals; Anisoles; Blood Proteins; Body Weight; Carbon Dis | 1969 |
Effect of phenobarbital and SKF 525A pretreatment on diphenylhydantoin teratogenicity in mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Depression, Chemical; Drug Synergism; Female; Fet | 1970 |
Controlling factors in urethan carcinogenesis in mice: effect of enzyme inducers and metabolic inhibitors.
Topics: Animals; Body Weight; Chlordan; Cycloheximide; Dactinomycin; Flavonoids; Hematocrit; Lung Neoplasms; | 1971 |
Tolerance to morphine in the white mice.
Topics: Aminopyrine; Animals; Behavior, Animal; Body Temperature; Body Weight; Drug Tolerance; Mice; Morphin | 1968 |
Further studies on the stimulation of L-(14C)-amino acid incorporation with cycloheximide.
Topics: Aminopyrine; Aniline Compounds; Animals; Antifungal Agents; Antipyrine; Body Weight; Carbon Isotopes | 1966 |