Page last updated: 2024-11-03

proadifen and Aging

proadifen has been researched along with Aging in 9 studies

Proadifen: An inhibitor of drug metabolism and CYTOCHROME P-450 ENZYME SYSTEM activity.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Diazepam was metabolized by human foetal liver microsomes to N-desmethyldiazepam and N-methyloxazepam as early as the 13th week of gestation."1.26Dizepam metabolism in human foetal and adult liver. ( Ackermann, E; Richter, K, 1977)
"6 Animals withdrawn following chronic administration of a number of drugs, barbitone, barbitone/bemegride mixture, Mandrax (methaqualone: diphenhydramine; 10: 1), chlordiazepoxide, nitrazepam, chlorpromazine or ethanol, exhibited a significant tolerance to intracerebroventricularly administered pentobarbitone."1.25A study of the factors affecting the sleeping time following intracerebroventricular administration of pentobarbitone sodium: effect of prior administration of centrally active drugs. ( Stevenson, IH; Turnbull, MJ, 1974)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KUNTZMAN, R1
JACOBSON, M1
SCHNEIDMAN, K1
CONNEY, AH1
Warszawski, D1
Ben-Zvi, Z1
Gorodischer, R1
James, RC1
Franklin, MR1
Ackermann, E1
Richter, K1
Smith, DA1
Stevenson, IH1
Turnbull, MJ1
Sato, T1
Moroi, K1
Gilbert, D1
Golberg, L1
Nery, R1

Other Studies

9 other studies available for proadifen and Aging

ArticleYear
SIMILARITIES BETWEEN OXIDATIVE DRUG-METABOLIZING ENZYMES AND STEROID HYDROXYLASES IN LIVER MICROSOMES.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 146

    Topics: Aging; Animals; Chlordan; Estradiol; Fatty Acids; Hexobarbital; Liver; Methylcholanthrene; Mice; Mic

1964
Caffeine metabolism in liver slices during postnatal development in the rat.
    Biochemical pharmacology, 1981, Dec-01, Volume: 30, Issue:23

    Topics: Aging; Allopurinol; Animals; Biotransformation; Caffeine; Chromatography, High Pressure Liquid; In V

1981
The triphasic amphetamine lethal dose curve in mice and its possible relationship to drug metabolism.
    Toxicology and applied pharmacology, 1978, Volume: 44, Issue:1

    Topics: Aging; Amphetamine; Animals; Anticonvulsants; Dextroamphetamine; Hexobarbital; In Vitro Techniques;

1978
Dizepam metabolism in human foetal and adult liver.
    European journal of clinical pharmacology, 1977, Volume: 11, Issue:1

    Topics: Aging; Carbon Monoxide; Dealkylation; Depression, Chemical; Diazepam; Female; Fetus; Gestational Age

1977
Aminopyrine N-demethylation in young, old and tumour bearing B6C3 F1 mice.
    Pharmacology & therapeutics, 1987, Volume: 33, Issue:1

    Topics: Aging; Aminopyrine; Animals; Carbon Dioxide; Dealkylation; Female; Kinetics; Male; Mice; Mice, Inbre

1987
A study of the factors affecting the sleeping time following intracerebroventricular administration of pentobarbitone sodium: effect of prior administration of centrally active drugs.
    British journal of pharmacology, 1974, Volume: 50, Issue:4

    Topics: Aging; Amphetamine; Animals; Anti-Anxiety Agents; Barbiturates; Body Weight; Carbon Radioisotopes; C

1974
Species differences in induction and inhibition of liver isocarboxazid hydrolase.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1973, Feb-22, Volume: 12, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Enzyme Induction; Female; Guinea Pigs; Hydrolases; In Vitro Techni

1973
BHT oxidase. A liver-microsomal enzyme induced by the treatment of rats with butylated hydroxytoluene.
    Food and cosmetics toxicology, 1967, Volume: 5, Issue:4

    Topics: Aging; Alcohols; Animals; Antioxidants; Chromatography, Thin Layer; Dactinomycin; Depression, Chemic

1967
Some aspects of the metabolism of urethane and N-hydroxyurethane in rodents.
    The Biochemical journal, 1968, Volume: 106, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Carbamates; Chloromercuribenzoates; Cyanides; Depression, Chemical

1968