primidone and Uremia
primidone has been researched along with Uremia in 3 studies
Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " The half-life was 5." | 1.26 | Pharmacokinetics of primidone elimination by uremic patients. ( Lee, CS; Marbury, TC; Perchalski, RT; Wilder, BJ, 1982) |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Lee, CS | 1 |
| Marbury, TC | 1 |
| Perchalski, RT | 1 |
| Wilder, BJ | 1 |
| Bosl, R | 1 |
| Shideman, JR | 1 |
| Meyer, RM | 1 |
| Buselmeier, TJ | 1 |
| von Hartitzsch, B | 1 |
| Kjellstrand, CM | 1 |
| Kurata, D | 1 |
| Wilkinson, GR | 1 |
Other Studies
3 other studies available for primidone and Uremia
| Article | Year |
|---|---|
Pharmacokinetics of primidone elimination by uremic patients.
Topics: Adult; Half-Life; Humans; Kinetics; Male; Middle Aged; Primidone; Renal Dialysis; Uremia | 1982 |
Effects and complications of high efficiency dialysis.
Topics: Barbiturates; Blood Urea Nitrogen; Body Weight; Calcium; Creatinine; Edema; Headache; Humans; Hypote | 1975 |
Erythrocyte uptake and plasma binding of diphenylhydantoin.
Topics: Carbon Radioisotopes; Dialysis; Erythrocytes; Ethosuximide; Female; Hematocrit; Humans; Hydroxylatio | 1974 |