primidone has been researched along with Tuberous Sclerosis in 2 studies
Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.
Tuberous Sclerosis: Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Radó, JP | 1 |
| Haris, A | 1 |
| Stern, EL | 1 |
2 other studies available for primidone and Tuberous Sclerosis
| Article | Year |
|---|---|
Metabolic bone disease (anticonvulsant osteomalacia) and renal tubular acidosis in tuberous sclerosis.
Topics: Acidosis, Renal Tubular; Adult; Back Pain; Bicarbonates; Bone and Bones; Calcitriol; Calcium; Calciu | 1993 |
Possible phenylethylmalondiamide (PEMA) intoxication.
Topics: Adult; Biotransformation; Female; Half-Life; Humans; Malonates; Phenylethylmalonamide; Primidone; Tu | 1977 |