Page last updated: 2024-11-03

primidone and Tremor

primidone has been researched along with Tremor in 76 studies

Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"We conducted a double-blind trial of isoniazid in 11 patients with essential tremor and four patients with other types of postural action tremor."9.07A double-blind trial of isoniazid for essential tremor and other action tremors. ( Dubinsky, RM; Gillespie, MM; Hallett, M; Moinfar, A; Ravits, J, 1991)
"Primidone, 50 to 1,000 mg/d, reduced the amplitude of essential tremor in both untreated and propranolol-treated patients."9.06Efficacy of primidone in essential tremor. ( Koller, WC; Royse, VL, 1986)
"In a double-blind cross-over trial, primidone was superior to both placebo and phenobarbital in reducing essential tremor in 13 patients."9.06Double-blind comparison of primidone and phenobarbital in essential tremor. ( Calzetti, S; Perucca, E; Sasso, E, 1988)
"Primidone was compared to the unselective beta adrenoceptor antagonist propranolol in the suppression of essential tremor."9.06Primidone and propranolol in essential tremor: a study based on quantitative tremor recording and plasma anticonvulsant levels. ( Dietrichson, P; Espen, E, 1987)
"The effects of placebo, propranolol and primidone were compared in 14 patients with essential tremor in a double blind, randomised, crossover study."9.06A comparison of primidone, propranolol, and placebo in essential tremor, using quantitative analysis. ( Campbell, MJ; Cooper, R; Gorman, WP; Pocock, P, 1986)
"Uncontrolled clinical studies have suggested that primidone may be effective in reducing essential tremor thus providing a valuable alternative to beta-adrenoreceptor antagonists which are currently the drugs of first choice."9.05Primidone in essential tremor of the hands and head: a double blind controlled clinical study. ( Calzetti, S; Cleeves, L; Findley, LJ, 1985)
"We treated 28 patients (16 women and 12 men) who had essential tremor with methazolamide."7.68Treatment of essential tremor with methazolamide. ( Caviness, JN; Daube, JR; Miller, PM; Muenter, MD, 1991)
"The long-term efficacy of primidone (375-750 mg/day) in essential tremor was evaluated prospectively in 11 patients who had shown a favorable response to 4-week treatment with the drug under placebo-controlled conditions."7.68Primidone in the long-term treatment of essential tremor: a prospective study with computerized quantitative analysis. ( Calzetti, S; Fava, R; Perucca, E; Sasso, E, 1990)
"We studied the acute and chronic effects of propranolol and primidone in essential tremor by administering long-acting propranolol (80 to 160 mg/d) and primidone (50 to 250 mg/d) to 50 patients."7.67Acute and chronic effects of propranolol and primidone in essential tremor. ( Koller, WC; Vetere-Overfield, B, 1989)
"To clarify whether primidone itself, and not only its metabolite phenobarbitone, suppresses essential tremor, the effect of a high single dose of primidone was tested."7.67Primidone and essential tremor. ( Holl, G; Honé, A; Seyfert, S, 1988)
"Primidone given to a patient for epilepsy produced an unexpected reduction in benign familial tremor."7.66Benign familial tremor treated with primidone. ( O'Brien, MD; Toseland, PA; Upton, AR, 1981)
"There are few medications for the treatment of essential tremor (ET)."6.72Primidone Intolerance in Essential tremor: Is it More than Just Age? ( Lenka, A; Louis, ED, 2021)
"We conducted a double-blind trial of isoniazid in 11 patients with essential tremor and four patients with other types of postural action tremor."5.07A double-blind trial of isoniazid for essential tremor and other action tremors. ( Dubinsky, RM; Gillespie, MM; Hallett, M; Moinfar, A; Ravits, J, 1991)
"The tremorolytic effects of primidone and phenobarbital in essential tremor of hands and head were compared in a double-blind, placebo-controlled trial."5.07Quantitative comparison of barbiturates in essential hand and head tremor. ( Calzetti, S; Fava, R; Perucca, E; Sasso, E, 1991)
"In a double-blind cross-over trial, primidone was superior to both placebo and phenobarbital in reducing essential tremor in 13 patients."5.06Double-blind comparison of primidone and phenobarbital in essential tremor. ( Calzetti, S; Perucca, E; Sasso, E, 1988)
"The effects of placebo, propranolol and primidone were compared in 14 patients with essential tremor in a double blind, randomised, crossover study."5.06A comparison of primidone, propranolol, and placebo in essential tremor, using quantitative analysis. ( Campbell, MJ; Cooper, R; Gorman, WP; Pocock, P, 1986)
"Primidone, 50 to 1,000 mg/d, reduced the amplitude of essential tremor in both untreated and propranolol-treated patients."5.06Efficacy of primidone in essential tremor. ( Koller, WC; Royse, VL, 1986)
"The effect of long-acting propranolol hydrochloride (160 mg/d), primidone (250 mg at night), and clonazepam (4 mg/d) on the resting, postural, and kinetic component of tremor was investigated in ten parkinsonian patients in a double-blind crossover design."5.06Adjuvant therapy of parkinsonian tremor. ( Herbster, G; Koller, WC, 1987)
"Primidone was compared to the unselective beta adrenoceptor antagonist propranolol in the suppression of essential tremor."5.06Primidone and propranolol in essential tremor: a study based on quantitative tremor recording and plasma anticonvulsant levels. ( Dietrichson, P; Espen, E, 1987)
"Uncontrolled clinical studies have suggested that primidone may be effective in reducing essential tremor thus providing a valuable alternative to beta-adrenoreceptor antagonists which are currently the drugs of first choice."5.05Primidone in essential tremor of the hands and head: a double blind controlled clinical study. ( Calzetti, S; Cleeves, L; Findley, LJ, 1985)
"In this systematic review we present information relating to the effectiveness and safety of the following interventions: adding mirtazepine to other antitremor drugs; benzodiazepines; beta-blockers other than propranolol; botulinum A toxin-haemagglutinin complex; calcium channel blockers; carbonic anhydrase inhibitors; clonidine; flunarizine; gabapentin; isoniazid; Phenobarbital; primidone; propranolol; and topiramate."4.84Essential tremor. ( Ferreira, JJ; Sampaio, C, 2007)
"The long-term efficacy of primidone (375-750 mg/day) in essential tremor was evaluated prospectively in 11 patients who had shown a favorable response to 4-week treatment with the drug under placebo-controlled conditions."3.68Primidone in the long-term treatment of essential tremor: a prospective study with computerized quantitative analysis. ( Calzetti, S; Fava, R; Perucca, E; Sasso, E, 1990)
"We treated 28 patients (16 women and 12 men) who had essential tremor with methazolamide."3.68Treatment of essential tremor with methazolamide. ( Caviness, JN; Daube, JR; Miller, PM; Muenter, MD, 1991)
"We studied the acute and chronic effects of propranolol and primidone in essential tremor by administering long-acting propranolol (80 to 160 mg/d) and primidone (50 to 250 mg/d) to 50 patients."3.67Acute and chronic effects of propranolol and primidone in essential tremor. ( Koller, WC; Vetere-Overfield, B, 1989)
"To clarify whether primidone itself, and not only its metabolite phenobarbitone, suppresses essential tremor, the effect of a high single dose of primidone was tested."3.67Primidone and essential tremor. ( Holl, G; Honé, A; Seyfert, S, 1988)
"Primidone given to a patient for epilepsy produced an unexpected reduction in benign familial tremor."3.66Benign familial tremor treated with primidone. ( O'Brien, MD; Toseland, PA; Upton, AR, 1981)
"There are few medications for the treatment of essential tremor (ET)."2.72Primidone Intolerance in Essential tremor: Is it More than Just Age? ( Lenka, A; Louis, ED, 2021)
"Essential tremor is not a benign condition; disability can be only partly reversed with drug therapy."2.66Disability in essential tremor: effect of treatment. ( Biary, N; Cone, S; Koller, W, 1986)
"Classical rest tremors are improved by dopaminergic substances or anticholinergics."2.44[Tremor. Differential diagnosis and treatment]. ( Raethjen, J; Wilms, H, 2008)
"Classical rest tremors are improved by dopaminergic substances (levodopa, dopamine agonists) or anticholinergics."2.44[Tremor]. ( Deuschl, G; Raethjen, J, 2007)
"ET tremor is usually characterized by symmetric bilateral postural and kinetic tremor, which may respond to low alcohol consumption."2.44[Diagnosis and treatment of tremor in Parkinson's disease and essential tremor]. ( Benecke, R; Wolters, A, 2007)
"Resting tremor in Parkinson's disease is usually not the primary disabling feature, and in most cases, levodopa/carbidopa is satisfactory for many years."2.43Pharmacological treatment of disabling tremor. ( Charles, PD; Duffis, EI; Schadt, CR, 2005)
"Monosymptomatic rest tremor has recently been shown to be associated with decreased fluorodopa uptake on the positron emission tomography scan suggesting its relationship to Parkinson disease."2.42Tremor. ( Sethi, KD, 2003)
"Tremor is a common movement disorder yet many physicians struggle with its terminology as well as with its treatment."2.42Tremor--easily seen but difficult to describe and treat. ( Grimes, DA, 2003)
"Essential tremor is the most prevalent adult-onset movement disorder, and is also regarded as one of the most common neurological disorders of adults, with a prevalence that is similar to or greater than that of stroke, Alzheimer disease, migraine headache, and lumbosacral pain syndromes."2.40A new twist for stopping the shakes? Revisiting GABAergic therapy for essential tremor. ( Louis, ED, 1999)
" The majority of our cases made some change in their daily medication dosage during the course of the study - 73."1.72Prospective, longitudinal analysis of medication use in a cohort of elderly essential tremor cases. ( Berry, DS; Delgado, N; Hernandez, DI; Louis, ED, 2022)
"We report on four cases of primary orthostatic tremor."1.31[Primary orthostatic tremor: report of 4 cases]. ( Cavallazzi, LO; Machado, SN; Matosinho, P; Pio, FJ, 2000)
"Orthostatic tremor is an unusual kind of potentially disabiling tremor appearing immediately when standing."1.30["Primary" orthostatic tremor. 10 clinical electrophysiologic observations]. ( Cassim, F; Destée, A; Guieu, JD; Mastain, B, 1998)
"Both patients were found to have a fine tremor in both legs on standing only."1.28[Orthostatic tremor]. ( Deisenhammer, F; Gerstenbrand, F; Ransmayr, G; Willeit, J, 1991)
"Orthostatic tremor is characterized by tremor of the trunk and legs while standing."1.28Orthostatic tremor: an association with essential tremor. ( FitzGerald, PM; Jankovic, J, 1991)
"Tremor is a rhythmic, involuntary muscular contraction with consistency of rate, amplitude and pattern."1.28Tremor. ( Gillespie, MM, 1991)
"Orthostatic tremor is characterized by its isolated occurrence in leg and trunk muscles during standing with undisturbed sitting, lying and walking."1.27[Orthostatic tremor: clinical aspects, pathophysiology and therapy]. ( Deuschl, G; Lücking, CH; Quintern, J, 1987)
"Hand tremor was present in 16 patients."1.27Essential tongue tremor. ( Biary, N; Koller, WC, 1987)
"Essential tremor is a common disorder whose aetiology is unknown."1.27Essential tremor. ( Findley, LJ, 1986)

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199038 (50.00)18.7374
1990's22 (28.95)18.2507
2000's12 (15.79)29.6817
2010's2 (2.63)24.3611
2020's2 (2.63)2.80

Authors

AuthorsStudies
Lenka, A1
Louis, ED3
Delgado, N1
Berry, DS1
Hernandez, DI1
James, L1
Ghosh, D1
Wilms, H1
Raethjen, J2
Ferreira, JJ1
Sampaio, C1
Lees, M1
Regier, L1
Jensen, B1
Grimes, DA1
Sethi, KD1
Schadt, CR1
Duffis, EI1
Charles, PD1
Budak, F1
Alemdar, M1
Kamaci, S1
Selekler, M1
Deuschl, G2
Wolters, A1
Benecke, R1
Findley, LJ7
Cleeves, L2
Tárczy, M2
Mogyorósi, I1
Takáts, A2
Csanda, E2
O'Brien, MD1
Upton, AR1
Toseland, PA1
Feely, M1
Calzetti, S7
Richens, A1
Procaccianti, G1
Martinelli, P1
Baruzzi, A1
Pazzaglia, P1
Lugarezi, E1
Gibb, WR1
Mogyorós, I1
Nielsen, E1
Chakrabarti, A1
Pearce, JM1
Munro, A1
Dave, M1
Metzer, WS1
Poersch, M1
Franz, DN1
Nguyen, PB1
Hart, LL1
Marchand, L1
Mastain, B1
Cassim, F1
Guieu, JD1
Destée, A1
Soler, R1
Vivancos, F1
Muñoz-Torrero, JJ1
Arpa, J1
Barreiro, P1
DiMario, FJ1
Cavallazzi, LO1
Machado, SN1
Matosinho, P1
Pio, FJ1
Masuhr, F1
Wissel, J1
Müller, J1
Scholz, U1
Poewe, W1
Bain, PG1
Forman, MB1
Chouler, C1
Milne, FJ1
Chadwick, D1
Reynolds, EH1
Marsden, CD1
Gillespie, MM2
Hallett, M1
Ravits, J1
Dubinsky, RM1
Moinfar, A1
Willeit, J1
Deisenhammer, F1
Ransmayr, G1
Gerstenbrand, F1
Koller, WC8
Muenter, MD1
Daube, JR1
Caviness, JN1
Miller, PM1
Guan, XM1
Peroutka, SJ1
Lou, JS1
Jankovic, J2
FitzGerald, PM1
Sasso, E5
Perucca, E5
Fava, R2
Negrotti, A1
Martines, C1
Gatti, G1
Diener, HC1
Goumentouk, AD1
Hurwitz, TA1
Zis, AP1
Vetere-Overfield, B1
Henkin, Y1
Herishanu, YO1
Dietrichson, P1
Espen, E1
Burton, K1
Koller, W1
Biary, N3
Cone, S1
Lücking, CH1
Quintern, J1
Herskovits, E1
Figueroa, E1
Mangone, C1
Seyfert, S1
Honé, A1
Holl, G1
van der Zwan, A1
Verwey, JC1
van Gijn, J1
Glatt, S1
Rubino, FA1
Kostić, V1
Pavlović, D1
Nikolić, M1
Gorman, WP1
Cooper, R1
Pocock, P1
Campbell, MJ1
Herbster, G1
Crystal, HA1
Royse, VL1
Martyn, B1
Young, RR1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Mechanism of Tremor Modulating Properties of Propranolol and Primidone in Essential Tremor: A Study With Transcranial Magnetic Stimulation and Eye Blink Classical Conditioning Paradigm[NCT04692844]61 participants (Actual)Observational2017-08-28Completed
Deep braIn Stimulation for Tremor TractographIC Versus Traditional[NCT02491554]24 participants (Anticipated)Interventional2015-08-31Recruiting
rTMS Therapy for Primary Orthostatic Tremor: A Novel Treatment Approach[NCT02441985]11 participants (Actual)Interventional2015-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

15 reviews available for primidone and Tremor

ArticleYear
Primidone Intolerance in Essential tremor: Is it More than Just Age?
    Tremor and other hyperkinetic movements (New York, N.Y.), 2021, Volume: 11

    Topics: Aged; Essential Tremor; Humans; Primidone; Tremor

2021
[Tremor. Differential diagnosis and treatment].
    Der Nervenarzt, 2008, Volume: 79, Issue:8

    Topics: Anticonvulsants; Botulinum Toxins; Deep Brain Stimulation; Diagnosis, Differential; Humans; Primidon

2008
Essential tremor.
    BMJ clinical evidence, 2007, May-01, Volume: 2007

    Topics: Double-Blind Method; Essential Tremor; Humans; Primidone; Propranolol; Tremor

2007
Tremor--easily seen but difficult to describe and treat.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2003, Volume: 30 Suppl 1

    Topics: Adrenergic beta-Antagonists; Anticonvulsants; Diagnosis, Differential; Essential Tremor; Humans; Pri

2003
Tremor.
    Current opinion in neurology, 2003, Volume: 16, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Diagnosis, Dif

2003
Pharmacological treatment of disabling tremor.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:3

    Topics: Botulinum Toxins, Type A; Dystonia; Essential Tremor; Humans; Parkinson Disease; Primidone; Proprano

2005
[Tremor].
    Therapeutische Umschau. Revue therapeutique, 2007, Volume: 64, Issue:1

    Topics: Adrenergic beta-Antagonists; Anticonvulsants; Antiparkinson Agents; Botulinum Toxins; Cholinergic Ag

2007
[Diagnosis and treatment of tremor in Parkinson's disease and essential tremor].
    MMW Fortschritte der Medizin, 2007, May-21, Volume: 149 Suppl 2

    Topics: Adrenergic beta-Antagonists; Amantadine; Anticonvulsants; Antiparkinson Agents; Deep Brain Stimulati

2007
Essential tremor: an overview.
    The Journal of the Arkansas Medical Society, 1994, Volume: 90, Issue:12

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Diagnosis, Differ

1994
Tremor in childhood.
    Pediatric annals, 1993, Volume: 22, Issue:1

    Topics: Adrenergic beta-Antagonists; Child; Humans; Primidone; Tremor

1993
Dronabinol in tremor.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:11

    Topics: Age Factors; Dronabinol; Female; Humans; Male; Parkinson Disease; Primidone; Propranolol; Tremor

1993
A new twist for stopping the shakes? Revisiting GABAergic therapy for essential tremor.
    Archives of neurology, 1999, Volume: 56, Issue:7

    Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric

1999
Basic mechanisms of action of drugs used in the treatment of essential tremor.
    Clinical neuropharmacology, 1990, Volume: 13, Issue:3

    Topics: Adrenergic beta-Antagonists; Central Nervous System Agents; Ethanol; Humans; Primidone; Tremor

1990
The pharmacological management of essential tremor.
    Clinical neuropharmacology, 1986, Volume: 9 Suppl 2

    Topics: Adrenergic beta-Antagonists; Ethanol; Humans; Phenobarbital; Primidone; Propranolol; Tremor

1986
Essential tremor: a review.
    Neurology, 1987, Volume: 37, Issue:7

    Topics: Adrenergic beta-Antagonists; Humans; Primidone; Tremor

1987

Trials

11 trials available for primidone and Tremor

ArticleYear
Benign familial tremor treated with primidone.
    British medical journal (Clinical research ed.), 1981, Jul-18, Volume: 283, Issue:6285

    Topics: Adult; Aged; Clinical Trials as Topic; Humans; Malonates; Middle Aged; Phenylethylmalonamide; Primid

1981
Benign familial tremor treated with primidone.
    British medical journal (Clinical research ed.), 1981, Aug-22, Volume: 283, Issue:6290

    Topics: Female; Humans; Male; Phenobarbital; Primidone; Tremor

1981
A double-blind trial of isoniazid for essential tremor and other action tremors.
    Movement disorders : official journal of the Movement Disorder Society, 1991, Volume: 6, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Double-Blind Method; Female; Humans; Isoniazid; Male; Midd

1991
Quantitative comparison of barbiturates in essential hand and head tremor.
    Movement disorders : official journal of the Movement Disorder Society, 1991, Volume: 6, Issue:1

    Topics: Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hand; Head; Humans; Ma

1991
Primidone and propranolol in essential tremor: a study based on quantitative tremor recording and plasma anticonvulsant levels.
    Acta neurologica Scandinavica, 1987, Volume: 75, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Female; Heart Rate; Humans; Male; Middle A

1987
Disability in essential tremor: effect of treatment.
    Neurology, 1986, Volume: 36, Issue:7

    Topics: Aged; Disabled Persons; Drug Therapy, Combination; Hand; Head; Humans; Male; Middle Aged; Motor Skil

1986
Double-blind comparison of primidone and phenobarbital in essential tremor.
    Neurology, 1988, Volume: 38, Issue:5

    Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Phenobarbital; Primidone; Tremor

1988
A comparison of primidone, propranolol, and placebo in essential tremor, using quantitative analysis.
    Journal of neurology, neurosurgery, and psychiatry, 1986, Volume: 49, Issue:1

    Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Primidone; Propran

1986
Adjuvant therapy of parkinsonian tremor.
    Archives of neurology, 1987, Volume: 44, Issue:9

    Topics: Aged; Antiparkinson Agents; Carbidopa; Clonazepam; Double-Blind Method; Drug Therapy, Combination; H

1987
Primidone in essential tremor of the hands and head: a double blind controlled clinical study.
    Journal of neurology, neurosurgery, and psychiatry, 1985, Volume: 48, Issue:9

    Topics: Adolescent; Adult; Aged; Ataxia; Clinical Trials as Topic; Double-Blind Method; Female; Hand; Head;

1985
Efficacy of primidone in essential tremor.
    Neurology, 1986, Volume: 36, Issue:1

    Topics: Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Phenobarbital; Primidone; Propranolol;

1986

Other Studies

50 other studies available for primidone and Tremor

ArticleYear
Prospective, longitudinal analysis of medication use in a cohort of elderly essential tremor cases.
    Journal of the neurological sciences, 2022, 11-15, Volume: 442

    Topics: Aged; Aged, 80 and over; Essential Tremor; Humans; Longitudinal Studies; Primidone; Propranolol; Tre

2022
Artistic Clues to Psychogenic Tremor Using Pen and Paper.
    The Journal of pediatrics, 2017, Volume: 190

    Topics: Adolescent; Diagnosis, Differential; Dystonic Disorders; Essential Tremor; Female; Humans; Neurologi

2017
Pharmacologic management of essential tremor.
    Canadian family physician Medecin de famille canadien, 2010, Volume: 56, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Anticonvulsants; Ethanol; Humans; Male; Phenobarbital; Primidone;

2010
Tremor in idiopathic distal acquired demyelinating symmetric neuropathy.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:11

    Topics: Aged; Anticonvulsants; Demyelinating Diseases; Functional Laterality; Humans; Male; Neural Conductio

2005
Tremor.
    British medical journal (Clinical research ed.), 1984, May-19, Volume: 288, Issue:6429

    Topics: Humans; Primidone; Propranolol; Tremor

1984
Treatment of essential tremor with Sertan.
    Therapia Hungarica (English edition), 1984, Volume: 32, Issue:3

    Topics: Aged; Humans; Middle Aged; Primidone; Tremor

1984
Benign familial tremor treated with primidone.
    British medical journal (Clinical research ed.), 1981, Jan-17, Volume: 282, Issue:6259

    Topics: Adolescent; Adult; Aged; Humans; Male; Middle Aged; Phenobarbital; Phenylethylmalonamide; Primidone;

1981
Benign familial tremor treated with primidone.
    British medical journal (Clinical research ed.), 1981, Feb-28, Volume: 282, Issue:6265

    Topics: Humans; Primidone; Tremor

1981
Double-blind controlled study of primidone in essential tremor.
    British medical journal (Clinical research ed.), 1982, Oct-16, Volume: 285, Issue:6348

    Topics: Female; Humans; Middle Aged; Primidone; Tremor

1982
Primidone in essential tremor.
    British medical journal (Clinical research ed.), 1982, Nov-13, Volume: 285, Issue:6352

    Topics: Humans; Primidone; Tremor

1982
[Treatment of essential tremor with Sertan].
    Orvosi hetilap, 1983, Apr-03, Volume: 124, Issue:14

    Topics: Age Factors; Aged; Basal Ganglia Diseases; Diagnosis, Differential; Humans; Male; Middle Aged; Parki

1983
[Treatment of familial tremor with primidone].
    Ugeskrift for laeger, 1983, May-23, Volume: 145, Issue:21

    Topics: Aged; Female; Humans; Primidone; Tremor

1983
Essential tremor: response to primidone.
    Journal of neurology, neurosurgery, and psychiatry, 1981, Volume: 44, Issue:7

    Topics: Aged; Female; Handwriting; Humans; Male; Middle Aged; Primidone; Tremor

1981
Essential tremor.
    Canadian Medical Association journal, 1981, Nov-01, Volume: 125, Issue:9

    Topics: Bipolar Disorder; Female; Humans; Lithium; Primidone; Tremor

1981
Two cases of risperidone-induced neuroleptic malignant syndrome.
    The American journal of psychiatry, 1995, Volume: 152, Issue:8

    Topics: Adult; Antipsychotic Agents; Female; Humans; Isoxazoles; Neuroleptic Malignant Syndrome; Piperidines

1995
Orthostatic tremor: combined treatment with primidone and clonazepam.
    Movement disorders : official journal of the Movement Disorder Society, 1994, Volume: 9, Issue:4

    Topics: Clonazepam; Drug Therapy, Combination; Electromyography; Female; Humans; Middle Aged; Posture; Primi

1994
[Treatment of essential tremor].
    L'union medicale du Canada, 1995, Volume: 124, Issue:3

    Topics: Anti-Anxiety Agents; Anti-Dyskinesia Agents; Botulinum Toxins; Humans; Hypnotics and Sedatives; Meth

1995
["Primary" orthostatic tremor. 10 clinical electrophysiologic observations].
    Revue neurologique, 1998, Volume: 154, Issue:4

    Topics: Adult; Aged; Anti-Anxiety Agents; Arm; Clonazepam; Diazepam; Electromyography; Female; Humans; Leg;

1998
Postural tremor after thalamic infarction.
    European neurology, 1999, Volume: 42, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Anticonvulsants; Arm; Cerebral Infarction; Female; Humans; Primid

1999
Childhood head tremor.
    Journal of child neurology, 2000, Volume: 15, Issue:1

    Topics: Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Male;

2000
[Primary orthostatic tremor: report of 4 cases].
    Arquivos de neuro-psiquiatria, 2000, Volume: 58, Issue:1

    Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Arm; Clonazepam; Depression; Diagnosis, Differential; E

2000
Quantification of sensory trick impact on tremor amplitude and frequency in 60 patients with head tremor.
    Movement disorders : official journal of the Movement Disorder Society, 2000, Volume: 15, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Anticonvulsants; Central Nervous System

2000
The management of tremor.
    Journal of neurology, neurosurgery, and psychiatry, 2002, Volume: 72 Suppl 1

    Topics: Botulinum Toxins, Type A; Brain; Cholinergic Antagonists; Clonazepam; Diagnosis, Differential; Elect

2002
Primidone-induced "uraemic flap".
    Lancet (London, England), 1979, Dec-08, Volume: 2, Issue:8154

    Topics: Epilepsy; Female; Humans; Kidney Failure, Chronic; Middle Aged; Primidone; Tremor

1979
Anticonvulsant-induced dyskinesias: a comparison with dyskinesias induced by neuroleptics.
    Journal of neurology, neurosurgery, and psychiatry, 1976, Volume: 39, Issue:12

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cerebellar Diseases; Chorea; Dyskinesia, Dr

1976
Tremor.
    The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 1991, Volume: 23, Issue:3

    Topics: Adrenergic beta-Antagonists; Humans; Patient Care Planning; Primidone; Tremor

1991
[Orthostatic tremor].
    Deutsche medizinische Wochenschrift (1946), 1991, Oct-04, Volume: 116, Issue:40

    Topics: Aged; Chronic Disease; Dose-Response Relationship, Drug; Electromyography; Humans; Male; Middle Aged

1991
A new drug for treatment of essential tremor? Time will tell.
    Mayo Clinic proceedings, 1991, Volume: 66, Issue:10

    Topics: Humans; Methazolamide; Primidone; Propranolol; Tremor

1991
Treatment of essential tremor with methazolamide.
    Mayo Clinic proceedings, 1991, Volume: 66, Issue:10

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Arm; Female; Head; Humans; Leg; Male; Methazolamide; Mi

1991
Essential tremor: clinical correlates in 350 patients.
    Neurology, 1991, Volume: 41, Issue:2 ( Pt 1)

    Topics: Adult; Aged; Aging; Alcohol Drinking; Female; Humans; Male; Middle Aged; Movement Disorders; Primido

1991
Orthostatic tremor: an association with essential tremor.
    Movement disorders : official journal of the Movement Disorder Society, 1991, Volume: 6, Issue:1

    Topics: Aged; Clonazepam; Drug Therapy, Combination; Electromyography; Humans; Male; Middle Aged; Muscles; P

1991
Acute tolerance to the tremorolytic effect of primidone.
    Neurology, 1991, Volume: 41, Issue:4

    Topics: Drug Tolerance; Humans; Male; Middle Aged; Placebos; Primidone; Time Factors; Tremor

1991
The disposition of primidone in elderly patients.
    British journal of clinical pharmacology, 1990, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Biotransformation; Chromatography, High Pressure

1990
[Tremor. Possibilities and limits of drug therapy].
    Medizinische Monatsschrift fur Pharmazeuten, 1990, Volume: 13, Issue:1

    Topics: Humans; Parasympatholytics; Parkinson Disease; Primidone; Propranolol; Tremor

1990
Primidone in the long-term treatment of essential tremor: a prospective study with computerized quantitative analysis.
    Clinical neuropharmacology, 1990, Volume: 13, Issue:1

    Topics: Aged; Anxiety; Computers; Female; Humans; Male; Middle Aged; Phenobarbital; Primidone; Prospective S

1990
Primidone in drug-induced tremor.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:6

    Topics: Amitriptyline; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fem

1989
Acute and chronic effects of propranolol and primidone in essential tremor.
    Neurology, 1989, Volume: 39, Issue:12

    Topics: Aged; Drug Evaluation; Female; Humans; Male; Primidone; Propranolol; Time Factors; Tremor

1989
Primidone as a treatment for cerebellar tremor in multiple sclerosis--two case reports.
    Israel journal of medical sciences, 1989, Volume: 25, Issue:12

    Topics: Adolescent; Adult; Cerebellar Diseases; Female; Humans; Multiple Sclerosis; Primidone; Tremor

1989
The treatment of tremor.
    The Medical journal of Australia, 1987, Nov-16, Volume: 147, Issue:10

    Topics: Adrenergic beta-Antagonists; Alcoholic Beverages; Cerebellar Diseases; Humans; Isoniazid; Levodopa;

1987
[Orthostatic tremor: clinical aspects, pathophysiology and therapy].
    EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete, 1987, Volume: 18, Issue:1

    Topics: Diagnosis, Differential; Electromyography; Evoked Potentials, Somatosensory; Female; Humans; Middle

1987
Hereditary essential tremor in Buenos Aires (Argentina).
    Arquivos de neuro-psiquiatria, 1988, Volume: 46, Issue:3

    Topics: Argentina; Diagnosis, Differential; Female; Gene Pool; Humans; Male; Pedigree; Primidone; Propranolo

1988
Primidone and essential tremor.
    Journal of neurology, 1988, Volume: 235, Issue:3

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Phenobarbital; Phenylethylmalonamide; Primidone; Tre

1988
Relief of orthostatic tremor by primidone.
    Neurology, 1988, Volume: 38, Issue:8

    Topics: Aged; Humans; Male; Posture; Primidone; Tremor

1988
Essential tremor variants: effect of treatment.
    Clinical neuropharmacology, 1987, Volume: 10, Issue:4

    Topics: Adult; Aged; Clonazepam; Female; Humans; Male; Middle Aged; Primidone; Propranolol; Tremor

1987
Essential tongue tremor.
    Movement disorders : official journal of the Movement Disorder Society, 1987, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Aged; Clonazepam; Coxsackievirus Infections; Electroencephalography; Ethanol; Fem

1987
[Essential tremor: therapeutic possibilities].
    Neurologija, 1987, Volume: 36, Issue:1-4

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Primidone; Propranolol; Tremor

1987
Essential tremor.
    British journal of hospital medicine, 1986, Volume: 35, Issue:6

    Topics: Diagnosis, Differential; Humans; Parkinson Disease; Phenobarbital; Phenylethylmalonamide; Primidone;

1986
Duration of effectiveness of primidone in essential tremor.
    Neurology, 1986, Volume: 36, Issue:11

    Topics: Aged; Female; Humans; Primidone; Tremor

1986
Writing tremor: its relationship to essential tremor.
    Journal of neurology, neurosurgery, and psychiatry, 1986, Volume: 49, Issue:2

    Topics: Handwriting; Humans; Male; Middle Aged; Primidone; Tremor

1986
Treatment of essential tremor--further comment.
    Annals of neurology, 1985, Volume: 18, Issue:3

    Topics: Humans; Primidone; Propranolol; Tremor

1985