primidone has been researched along with Stevens-Johnson Syndrome in 5 studies
Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Handfield-Jones, SE | 1 |
| Jenkins, RE | 1 |
| Whittaker, SJ | 1 |
| Besse, CP | 1 |
| McGibbon, DH | 1 |
| Pollack, MA | 1 |
| Burk, PG | 1 |
| Nathanson, G | 1 |
| Böttiger, LE | 1 |
| Strandberg, I | 1 |
| Westerholm, B | 1 |
| Muhar, U | 1 |
| Granditsch, G | 1 |
| Diem, E | 1 |
| Stüttgen, G | 1 |
5 other studies available for primidone and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
The anticonvulsant hypersensitivity syndrome.
Topics: Adult; Anticonvulsants; Bronchial Diseases; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Fa | 1993 |
Mucocutaneous eruptions due to antiepileptic drug therapy in children.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Erythema Multiforme; Female; Humans; Male; | 1979 |
Drug-induced febrile mucocutaneous syndrome with a survey of the literature.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Child, Preschool; Female; Humans; Infant; Male; Middl | 1975 |
Toxic epidermal necrolysis due to antiepileptic therapy in an 8-year-old boy.
Topics: Adult; Anticonvulsants; Child; Diagnosis, Differential; Humans; Infant; Male; Phenytoin; Primidone; | 1985 |
Toxic epidermal necrolysis provoked by barbiturates.
Topics: Adrenal Cortex Hormones; Aged; Endocarditis; Female; Gastrointestinal Hemorrhage; Humans; Phenobarbi | 1973 |