primidone has been researched along with Spasms, Infantile in 4 studies
Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.
Spasms, Infantile: An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The therapeutics results with the use of different drugs (diazepam, nitrazepam, clonazepam, diphenylhydantoin, barbiturates--phenobarbital and primidone--, sodium dipropylacetate and ACTH) in twenty-nine patients with Lennox--Gastaut syndrome are carefully analysed." | 3.65 | [Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome]. ( Lison, MP; Speciali, GG, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| JIMENEZESPINOSA, L | 1 |
| Kiul'ts, I | 1 |
| Klaĭf, F | 1 |
| Aucamp, AK | 1 |
| Speciali, GG | 1 |
| Lison, MP | 1 |
1 review available for primidone and Spasms, Infantile
| Article | Year |
|---|---|
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, | 1979 |
3 other studies available for primidone and Spasms, Infantile
| Article | Year |
|---|---|
[THERAPY OF EPILEPSY].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Chlordiazepoxide; Epilepsy; Epilepsy, Temporal Lobe; H | 1964 |
[Treatment of rapid nodding "salaam" spasms in childhood].
Topics: Adrenocorticotropic Hormone; Child, Preschool; Clonazepam; Electroencephalography; Female; Humans; I | 1980 |
[Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, Preschool; Clonazepam; Dia | 1977 |