primidone has been researched along with Recrudescence in 13 studies
Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Intermittent diazepam prophylaxis at times of fever may or may not reduce the recurrence rate significantly, but there is no data to suggest that it improves the long-term outcome, as compared with short-term seizure control, in terms of IQ, cognition, academic progress, motor control, and subsequent epilepsy." | 4.81 | [Febrile convulsions, Treatment and prognosis]. ( Knudsen, FU, 2001) |
| "A 74 year old man presented to the Old Age Psychiatry Service with cognitive deficits while being treated for recurrent depressive episodes and essential tremor with Venlafaxine, Lithium, and Primidone." | 3.81 | Drug-induced cerebral glucose metabolism resembling Alzheimer's Disease: a case study. ( Beer, AJ; Riepe, MW; Vonend, C; Walther, B, 2015) |
| "The most important factor determining seizure recurrence was continued therapy, which was the case for barbiturates, phenytoin and valproate." | 2.69 | Does withdrawal of different antiepileptic drugs have different effects on seizure recurrence? Further results from the MRC Antiepileptic Drug Withdrawal Study. ( Chadwick, D, 1999) |
| "The recurrence rate of febrile convulsions is assessed in 108 children who had had either prolonged or repeated initial fits or had both a positive family history and persisting neurological disorder." | 2.64 | Continuous phrophylcatic anticonvulsants in selected childrens with febrile convulsions. ( Wallace, SJ, 1975) |
| "There was a greater risk of recurrence among girls." | 1.28 | [Factors influencing the effectiveness of preventive treatment of febrile convulsions]. ( Armijo Simón, JA; Arteaga Manjón-Cabeza, R; Herranz Fernández, JL, 1989) |
| " The remaining 95 children were given sodium valproate; the dosage was 20-25 mg/kg/day b." | 1.26 | Phenobarbital, primidone and sodium valproate in the prophylaxis of febrile convulsions. ( Minagawa, K; Miura, H, 1981) |
| " Reduction in antiepileptic drug dosage should be carried out as a stepwise procedure over a period of about 2 years." | 1.25 | [A discussion of the curability of childhood epilepsies (author's transl)]. ( Groh, C, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (76.92) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Riepe, MW | 1 |
| Walther, B | 1 |
| Vonend, C | 1 |
| Beer, AJ | 1 |
| HAMFELT, A | 1 |
| KILLANDER, A | 1 |
| MALERS, E | 1 |
| DEVERDIER, CH | 1 |
| Minagawa, K | 1 |
| Miura, H | 1 |
| Holliday, TA | 1 |
| Chadwick, D | 1 |
| Knudsen, FU | 1 |
| May, CJ | 1 |
| Greenwood, RE | 1 |
| Groh, C | 1 |
| Wallace, SJ | 1 |
| Herranz Fernández, JL | 1 |
| Armijo Simón, JA | 1 |
| Arteaga Manjón-Cabeza, R | 1 |
| Schmidt, D | 1 |
| Reininghaus, R | 1 |
| Winkel, R | 1 |
| Gold, AP | 1 |
| Wilson, JT | 1 |
| Wilkinson, GR | 1 |
2 reviews available for primidone and Recrudescence
| Article | Year |
|---|---|
Seizure disorders.
Topics: Animals; Cat Diseases; Cats; Diagnosis, Differential; Diazepam; Dog Diseases; Dogs; Epilepsy; Mephob | 1980 |
[Febrile convulsions, Treatment and prognosis].
Topics: Analgesics, Non-Narcotic; Anticonvulsants; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phe | 2001 |
2 trials available for primidone and Recrudescence
| Article | Year |
|---|---|
Does withdrawal of different antiepileptic drugs have different effects on seizure recurrence? Further results from the MRC Antiepileptic Drug Withdrawal Study.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Combinations; Epilepsy; Female; Human | 1999 |
Continuous phrophylcatic anticonvulsants in selected childrens with febrile convulsions.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Female; Fever; Follow-Up Studies; Humans; Infant; | 1975 |
9 other studies available for primidone and Recrudescence
| Article | Year |
|---|---|
Drug-induced cerebral glucose metabolism resembling Alzheimer's Disease: a case study.
Topics: Aged; Alzheimer Disease; Anticonvulsants; Antidepressive Agents; Attention; Cognition Disorders; Dep | 2015 |
MEGALOBLASTIC ANAEMIA ASSOCIATED WITH ANTICONVULSANT DRUGS: STUDIES ON A CASE WITH FOUR RELAPSES.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Drug Therapy; Electrophoresis; Epilepsy; | 1965 |
Phenobarbital, primidone and sodium valproate in the prophylaxis of febrile convulsions.
Topics: Child, Preschool; Dose-Response Relationship, Drug; Humans; Infant; Phenobarbital; Primidone; Recurr | 1981 |
Recurrent convulsions in a thoroughbred foal: management and treatment.
Topics: Animals; Animals, Newborn; Enteral Nutrition; Female; Horse Diseases; Horses; Male; Pregnancy; Primi | 1977 |
[A discussion of the curability of childhood epilepsies (author's transl)].
Topics: Barbiturates; Benzodiazepines; Carbamazepine; Child; Drug Therapy, Combination; Epilepsies, Partial; | 1975 |
[Factors influencing the effectiveness of preventive treatment of febrile convulsions].
Topics: Anticonvulsants; Child; Drug Evaluation; Epilepsy; Female; Fever; Humans; Male; Phenobarbital; Primi | 1989 |
Relevance of poor compliance for seizure control.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Middle Aged; Patient Compliance | 1988 |
Psychomotor epilepsy in childhood.
Topics: Bromides; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; E | 1974 |
Delivery of anticonvulsant drug therapy in epileptic patients assessed by plasma level analyses.
Topics: Adolescent; Adult; Child; Chromatography, Gas; Drug Therapy; Electroencephalography; Epilepsy; Human | 1974 |