primidone has been researched along with Neurovisceral Storage Disease with Vertical Supranuclear Ophthalmoplegia in 1 studies
Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Like valproic acid, treatment with primidone reduced free-C levels in LE/LY in NPC1-null/mutant cells." | 5.62 | Beneficial effects of primidone in Niemann-Pick disease type C (NPC)-model cells and mice: Reduction of unesterified cholesterol levels in cells and extension of lifespan in mice. ( Ashikawa, H; Honda, T; Mogi, H; Murayama, T; Nakamura, H, 2021) |
| "Like valproic acid, treatment with primidone reduced free-C levels in LE/LY in NPC1-null/mutant cells." | 1.62 | Beneficial effects of primidone in Niemann-Pick disease type C (NPC)-model cells and mice: Reduction of unesterified cholesterol levels in cells and extension of lifespan in mice. ( Ashikawa, H; Honda, T; Mogi, H; Murayama, T; Nakamura, H, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashikawa, H | 1 |
| Mogi, H | 1 |
| Honda, T | 1 |
| Nakamura, H | 1 |
| Murayama, T | 1 |
1 other study available for primidone and Neurovisceral Storage Disease with Vertical Supranuclear Ophthalmoplegia
| Article | Year |
|---|---|
Beneficial effects of primidone in Niemann-Pick disease type C (NPC)-model cells and mice: Reduction of unesterified cholesterol levels in cells and extension of lifespan in mice.
Topics: Animals; Biological Transport; CHO Cells; Cholesterol; Cricetulus; Disease Models, Animal; Endoplasm | 2021 |