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primidone and Myoclonic Jerk

primidone has been researched along with Myoclonic Jerk in 18 studies

Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.

Research Excerpts

ExcerptRelevanceReference
"Senegalese baboons (Papio papio), with a natural syndrome of photosensitive epilepsy, consistently show generalized myoclonic jerks if stimulated stroboscopically at hourly intervals, two to eight hours after the intravenous administration of allylglycine, 200 mg/kg."3.65A primate model for testing anticonvulsant drugs. ( Horton, RW; Meldrum, BS; Toseland, PA, 1975)
"A patient with posthypoxic cortical action myoclonus was studied using polygraphic EEG-EMG recording techniques and transcranial magnetic stimulation."1.33Rhythmic EMG and EEG activity during voluntary movement in posthypoxic cortical action myoclonus. ( Hashimoto, T; Tamagawa, A; Tsuji, S; Uozumi, T, 2005)
"Ten patients with severe disabling myoclonus were treated with clonazepam, sodium valproate, primidone and piracetam alone, or in different combinations."1.28The treatment of severe action myoclonus. ( Artieda, J; Day, B; Marsden, CD; Obeso, JA; Rothwell, JC; Thompson, P, 1989)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199017 (94.44)18.7374
1990's0 (0.00)18.2507
2000's1 (5.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
TIMBERLAKE, WH1
ABBOTT, JA1
SCHWAB, RS1
Uozumi, T1
Tamagawa, A1
Hashimoto, T1
Tsuji, S1
Shea, JJ1
Emmett, JR1
Hanson, JW1
Smith, DW1
Meldrum, BS1
Horton, RW1
Toseland, PA1
Obeso, JA1
Artieda, J1
Rothwell, JC1
Day, B1
Thompson, P1
Marsden, CD1
Laitinen, L1
Toivakka, E1
Sibley, WA1
Völzke, E1
Doose, H1
Huang, CY2
McLeod, JG2
Sampson, D2
Hensley, WJ2
Millichap, JG1
Livingston, S1
Villamater, C1
Sakata, Y1
Schulze, B1
Boudouresques, J1
Roger, J1
Khalil, R1
Vigouroux, RA1
Gosset, A1
Pellissier, JF1
Tassinari, CA1
Brooks, JE1
Jirauch, PM1
Williamson, DA1
Dzialek, E1
Góral, Z1

Reviews

1 review available for primidone and Myoclonic Jerk

ArticleYear
Diagnosis and treatment of epilepsy: overview and general principles.
    Pediatrics, 1974, Volume: 53, Issue:4

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination;

1974

Trials

1 trial available for primidone and Myoclonic Jerk

ArticleYear
Ospolot (sulthiame) in epilepsy. (Preliminary report).
    Diseases of the nervous system, 1967, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy, Tem

1967

Other Studies

16 other studies available for primidone and Myoclonic Jerk

ArticleYear
Mysoline; an effective anticonvulsant with initial problems of adjustment.
    The New England journal of medicine, 1955, Feb-24, Volume: 252, Issue:8

    Topics: Adaptation, Psychological; Anticonvulsants; Epilepsy; Myoclonus; Primidone

1955
Rhythmic EMG and EEG activity during voluntary movement in posthypoxic cortical action myoclonus.
    Journal of UOEH, 2005, Sep-01, Volume: 27, Issue:3

    Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Electromyography; Humans; Hypoxi

2005
The medical treatment of tinnitus.
    The Journal of laryngology and otology. Supplement, 1981, Issue:4

    Topics: Adult; Carbamazepine; Diethylcarbamazine; Female; Humans; Lidocaine; Myoclonus; Phenytoin; Primidone

1981
The fetal hydantoin syndrome.
    The Journal of pediatrics, 1975, Volume: 87, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Child, Preschool; Developmental Di

1975
A primate model for testing anticonvulsant drugs.
    Archives of neurology, 1975, Volume: 32, Issue:5

    Topics: Allyl Compounds; Animals; Anticonvulsants; Carbamazepine; Chromatography, Gas; Diazepam; Disease Mod

1975
The treatment of severe action myoclonus.
    Brain : a journal of neurology, 1989, Volume: 112 ( Pt 3)

    Topics: Adolescent; Adult; Aged; Clonazepam; Drug Evaluation; Drug Therapy, Combination; Electromyography; E

1989
Clonazepam (Ro 5-4023) in the treatment of myoclonus epilepsy. Four case reports.
    Acta neurologica Scandinavica. Supplementum, 1973, Volume: 53

    Topics: Adult; Anticonvulsants; Benzodiazepinones; Chlorobenzenes; Diazepam; Drug Therapy, Combination; Elec

1973
Dipropylacetate (Dépakine, Ergenyl) in the treatment of epilepsy.
    Epilepsia, 1973, Volume: 14, Issue:2

    Topics: Adolescent; Anticonvulsants; Barbiturates; Child; Child, Preschool; Drug Synergism; Electroencephalo

1973
Clonazepam in the treatment of epilepsy.
    The Medical journal of Australia, 1974, Jul-06, Volume: 2, Issue:1

    Topics: Adult; Anticonvulsants; Benzodiazepinones; Chlorobenzenes; Chromatography, Gas; Drug Interactions; E

1974
Drug treatment of convulsive disorders.
    The New England journal of medicine, 1972, Mar-02, Volume: 286, Issue:9

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Barbiturates; Child; Diazepam; E

1972
Clonazepam in the treatment of epilepsy.
    Proceedings of the Australian Association of Neurologists, 1973, Volume: 10, Issue:0

    Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Chlorobenzenes; Chromatography, Gas; Drug Int

1973
[Problem of drug-induced cerebral reactions: a case of myoclonic state under treatment with tricyclic antidepressive agents].
    Der Nervenarzt, 1972, Volume: 43, Issue:6

    Topics: Adult; Amitriptyline; Bipolar Disorder; Chlordiazepoxide; Dibenzazepines; Electrocardiography; Femal

1972
[2 cases of the Lance and Adams syndrome. Therepeutic action of RO-05-4023].
    Revue neurologique, 1971, Volume: 125, Issue:4

    Topics: Adolescent; Amides; Diazepam; Dibenzazepines; Electroencephalography; Electromyography; Humans; Hypo

1971
Primary reading epilepsy: a misnomer.
    Archives of neurology, 1971, Volume: 25, Issue:2

    Topics: Adult; Electroencephalography; Electromyography; Electrooculography; Epilepsy; Eye Movements; Handwr

1971
Fits in utero, followed by infantile myoclonic twitchings.
    Proceedings of the Royal Society of Medicine, 1968, Dec-12, Volume: 61, Issue:12

    Topics: Adult; Female; Fetal Diseases; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Myoclonus;

1968
[Therapeutic effect of mizodin and luminal in a case of Friedreich's paramyoclonus multiplex in a child].
    Neurologia, neurochirurgia i psychiatria polska, 1966, Volume: 16, Issue:7

    Topics: Adolescent; Humans; Male; Myoclonus; Phenobarbital; Primidone

1966