primidone has been researched along with Multiple Sclerosis in 2 studies
Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Henkin, Y | 1 |
Herishanu, YO | 1 |
Cendrowski, W | 1 |
Majkowski, J | 1 |
2 other studies available for primidone and Multiple Sclerosis
Article | Year |
---|---|
Primidone as a treatment for cerebellar tremor in multiple sclerosis--two case reports.
Topics: Adolescent; Adult; Cerebellar Diseases; Female; Humans; Multiple Sclerosis; Primidone; Tremor | 1989 |
Epilepsy in multiple sclerosis.
Topics: Adolescent; Adult; Barbiturates; Basal Ganglia; Carbamazepine; Cerebral Cortex; Demyelinating Diseas | 1972 |