primidone and Liver Dysfunction studies

primidone and Liver Dysfunction

primidone has been researched along with Liver Dysfunction in 4 studies

Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.

Research Excerpts

Excerpt	Relevance	Reference
"Anticonvulsant therapy was among the first areas to benefit from clinical pharmacokinetic studies."	2.35	Clinical pharmacokinetics of anticonvulsants. ( Dam, M; Hvidberg, EF, 1976)

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

4 (100.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
MARCHAND, L	1
TEULIE, G	1
BALIER, C	1
Bruni, J	1
Albright, PS	1
Hvidberg, EF	1
Dam, M	1
Bunch, SE	1
Conway, MB	1
Center, SA	1
Castleman, WL	1
Baldwin, BH	1
Hornbuckle, WE	1
Tennant, BC	1

Studies

MARCHAND, L

TEULIE, G

BALIER, C

Bruni, J

Albright, PS

Hvidberg, EF

Dam, M

Bunch, SE

Conway, MB

Center, SA

Castleman, WL

Baldwin, BH

Hornbuckle, WE

Tennant, BC

Reviews

2 reviews available for primidone and Liver Dysfunction

Article	Year
The clinical pharmacology of antiepileptic drugs. Clinical neuropharmacology, 1984, Volume: 7, Issue:1 Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Hal	1984
Clinical pharmacokinetics of anticonvulsants. Clinical pharmacokinetics, 1976, Volume: 1, Issue:3 Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam	1976

Article

Year

The clinical pharmacology of antiepileptic drugs.

Clinical neuropharmacology, 1984, Volume: 7, Issue:1

Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Hal

1984

Clinical pharmacokinetics of anticonvulsants.

Clinical pharmacokinetics, 1976, Volume: 1, Issue:3

Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam

1976

Other Studies

2 other studies available for primidone and Liver Dysfunction

Article	Year
[Leukemia in an epileptic treated with gardenal and dihydan; recovery; fatal mysoline poisoning with fatty degeneration of the liver and acute epithelial nephritis]. Annales medico-psychologiques, 1955, Volume: 113 1, Issue:2 Topics: Anticonvulsants; Barbiturates; Epilepsy; Humans; Hydantoins; Leukemia; Leukocytosis; Liver Diseases;	1955
Toxic hepatopathy and intrahepatic cholestasis associated with phenytoin administration in combination with other anticonvulsant drugs in three dogs. Journal of the American Veterinary Medical Association, 1987, Jan-15, Volume: 190, Issue:2 Topics: Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Dog Dis	1987

Article

Year

[Leukemia in an epileptic treated with gardenal and dihydan; recovery; fatal mysoline poisoning with fatty degeneration of the liver and acute epithelial nephritis].

Annales medico-psychologiques, 1955, Volume: 113 1, Issue:2

Topics: Anticonvulsants; Barbiturates; Epilepsy; Humans; Hydantoins; Leukemia; Leukocytosis; Liver Diseases;

1955

Toxic hepatopathy and intrahepatic cholestasis associated with phenytoin administration in combination with other anticonvulsant drugs in three dogs.

Journal of the American Veterinary Medical Association, 1987, Jan-15, Volume: 190, Issue:2

Topics: Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Dog Dis

1987