primidone has been researched along with Epilepsy, Temporal Lobe in 66 studies
Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.
Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).
| Excerpt | Relevance | Reference |
|---|---|---|
| "An epileptic patient whose seizures were controlled with carbamazepine and primidone was followed throughout pregnancy and lactation." | 7.66 | Carbamazepine levels in pregnancy and lactation. ( Blake, DA; Freeman, JM; Luff, RD; Niebyl, JR, 1979) |
| "Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)." | 7.65 | Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975) |
| "An epileptic patient whose seizures were controlled with carbamazepine and primidone was followed throughout pregnancy and lactation." | 3.66 | Carbamazepine levels in pregnancy and lactation. ( Blake, DA; Freeman, JM; Luff, RD; Niebyl, JR, 1979) |
| "Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)." | 3.65 | Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975) |
| "Phenytoin serum concentrations in 115 epileptics treated on an inpatient basis showed, in two groups, only relatively weak correlation with the dosage used." | 1.26 | [Clinical significance of serum phenytoin level]. ( Oettinger, B; Richter, K, 1978) |
| "Successful treatment of partial complex seizures (and the epilepsies in general) is a process of management over time and involves several factors." | 1.25 | Management of the difficult patient with complex partial seizures. ( Booker, HE, 1975) |
| "Although sneezing is a particularly common symptom, there are surprisingly few references to this subject in the medical literature." | 1.24 | PAROXYSMAL SNEEZING. ( KOFMAN, O, 1964) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 66 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ZIVIN, I | 1 |
| ROWLEY, W | 1 |
| DOBER, B | 1 |
| GIBBS, FA | 1 |
| RICH, CL | 1 |
| GIBBS, EL | 1 |
| JIMENEZESPINOSA, L | 1 |
| JONGMANS, JW | 1 |
| KOFMAN, O | 1 |
| Schmidt, D | 4 |
| Tsai, JJ | 1 |
| Janz, D | 1 |
| Rowan, AJ | 1 |
| Trimble, MR | 1 |
| Bruni, J | 1 |
| Tassinari, CA | 1 |
| Roger, J | 1 |
| Feldman, RG | 1 |
| Livingston, S | 2 |
| Pauli, LL | 1 |
| Oettinger, B | 1 |
| Richter, K | 1 |
| Aucamp, AK | 1 |
| Karbowski, K | 2 |
| Hosokawa, K | 1 |
| Kugoh, T | 1 |
| Otsuki, S | 1 |
| Niebyl, JR | 1 |
| Blake, DA | 1 |
| Freeman, JM | 2 |
| Luff, RD | 1 |
| Shaywitz, BA | 1 |
| Cohen, DJ | 1 |
| Bowers, MB | 1 |
| Singer, HS | 1 |
| Richens, A | 2 |
| Rodin, EA | 1 |
| Rim, CS | 1 |
| Kitano, H | 1 |
| Lewis, R | 1 |
| Rennick, PM | 1 |
| Meienberg, O | 1 |
| Thomas, JA | 1 |
| Knotts, GR | 1 |
| Van Buren, JM | 1 |
| Ajmone-Marsan, C | 1 |
| Mutsuga, N | 1 |
| Sadowsky, D | 1 |
| Bachelard, HS | 1 |
| Thompson, MF | 1 |
| Polkey, CE | 1 |
| Booker, HE | 1 |
| Cate JC, IV | 1 |
| Tenser, R | 1 |
| Houghton, GW | 1 |
| Toseland, PA | 1 |
| Davidson, S | 2 |
| Ramana, R | 1 |
| Silverstone, PH | 1 |
| Lishman, WA | 1 |
| Cornaggia, CM | 1 |
| Canevini, MP | 1 |
| Giuccioli, D | 1 |
| Pruneri, C | 1 |
| Canger, R | 1 |
| Reid, TL | 1 |
| Raj, BA | 1 |
| Sheehan, DR | 1 |
| Benetello, P | 1 |
| Furlanut, M | 1 |
| Stefan, H | 1 |
| Sibley, WA | 1 |
| Parsonage, M | 1 |
| Dano, P | 1 |
| Völzke, E | 1 |
| Doose, H | 1 |
| Billinghurst, JR | 1 |
| German, GA | 1 |
| Orley, JH | 1 |
| Cereghino, JJ | 1 |
| Brock, JT | 1 |
| Van Meter, JC | 1 |
| Penry, JK | 1 |
| Smith, LD | 1 |
| Fisher, P | 1 |
| Ellenberg, J | 1 |
| Gold, AP | 1 |
| Huang, CY | 1 |
| McLeod, JG | 1 |
| Sampson, D | 1 |
| Hensley, WJ | 1 |
| Liu, MC | 1 |
| Villamater, C | 1 |
| Sakata, Y | 1 |
| Gibberd, FB | 1 |
| Wilson, J | 1 |
| Ritter, G | 1 |
| Henriksen, GF | 1 |
| Birket-Smith, E | 1 |
| Lund, M | 1 |
| Mikkelsen, B | 1 |
| Vestermark, S | 1 |
| Olsen, PZ | 1 |
| Holm, P | 1 |
| Travers, RD | 2 |
| Reynolds, EH | 1 |
| Gallagher, BB | 4 |
| Baumel, IP | 2 |
| Mattson, RH | 2 |
| Cooper, IS | 1 |
| Crighel, E | 1 |
| Amin, I | 1 |
| Vajda, F | 1 |
| Williams, FM | 1 |
| Falconer, MA | 1 |
| Breckenridge, A | 1 |
| Gudmundsson, G | 1 |
| Matthes, A | 1 |
| Olesen, OV | 1 |
| Dam, M | 1 |
| Roth, G | 1 |
| Borkowska, Z | 1 |
| Mazurkowa, K | 1 |
| Wojakowski, A | 1 |
| Karnes, WE | 1 |
| Glaser, GH | 1 |
| Beĭn, BN | 1 |
| Beliaev, IuI | 1 |
| Boreĭko, VB | 1 |
| Lou, HO | 1 |
4 reviews available for primidone and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Diagnosis and treatment of epilepsy.
Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; E | 1983 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, | 1979 |
[The psycho-motor epilepsy (author's transl)].
Topics: Adolescent; Adult; Brain Injuries; Carbamazepine; Child; Diagnosis, Differential; Diseases in Twins; | 1978 |
Diagnosis and treatment of epilepsy: overview and general principles.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; | 1974 |
6 trials available for primidone and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Single drug therapy for intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy, Temporal Lobe; Humans; Mi | 1983 |
Evaluation of albutoin as an antiepileptic drug.
Topics: Adolescent; Adult; Allyl Compounds; Analysis of Variance; Anticonvulsants; Appetite; Biopharmaceutic | 1974 |
Ospolot (sulthiame) in epilepsy. (Preliminary report).
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy, Tem | 1967 |
A controlled trial on Ro 5-4023 (clonazepam) in the treatment of psychomotor epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Carbamazepine; Child; Chlorobenzenes; Clinica | 1973 |
The metabolic conversion of primidone (Mysoline) to phenobarbitone in patients under long-term treatment. An attempt to estimate the independent effect of primidone.
Topics: Adult; Behavior; Clinical Trials as Topic; Drug Synergism; Electroencephalography; Epilepsy; Epileps | 1967 |
Oxazepam in the treatment of psychomotor epilepsy.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Electroencephalography; Epilepsy, Temporal | 1968 |
56 other studies available for primidone and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
PSYCHOMOTOR EPILEPSY WITH MICTURITION.
Topics: Adolescent; Electroencephalography; Epilepsy; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Hu | 1964 |
[THERAPY OF CONVULSIVE DISEASES].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Dexamethasone; Epilepsy; Epilepsy, Absen | 1963 |
PSYCHOMOTOR VARIANT TYPE OF SEIZURE DISCHARGE.
Topics: Adolescent; Anticonvulsants; Child; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, T | 1963 |
[THERAPY OF EPILEPSY].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Chlordiazepoxide; Epilepsy; Epilepsy, Temporal Lobe; H | 1964 |
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepox | 1964 |
PAROXYSMAL SNEEZING.
Topics: Anticonvulsants; Child; Child Psychiatry; Epilepsy; Epilepsy, Temporal Lobe; Humans; Hydantoins; Met | 1964 |
Generalized tonic-clonic seizures in patients with complex-partial seizures: natural history and prognostic relevance.
Topics: Carbamazepine; Epilepsies, Myoclonic; Epilepsy, Temporal Lobe; Humans; Phenytoin; Primidone; Prognos | 1983 |
Prognosis of chronic epilepsy with complex partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electro | 1984 |
Dementia in epilepsy.
Topics: Adult; Anticonvulsants; Brain Injuries; Dementia; Epilepsy; Epilepsy, Temporal Lobe; Humans; Middle | 1984 |
Valproic acid and plasma levels of primidone and derived phenobarbital.
Topics: Adult; Drug Interactions; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Female; Humans; Kineti | 1981 |
Two antiepileptic drugs for intractable epilepsy with complex-partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epileps | 1982 |
Prognosis and therapy of complex partial seizures with barbiturates, hydantoins, and other drugs.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Drug Therapy, Combination; Epilepsy; Epilepsy, Tempo | 1975 |
Chlorazepate in temporal lobe epilepsy.
Topics: Aggression; Anti-Anxiety Agents; Clorazepate Dipotassium; Drug Interactions; Epilepsy, Temporal Lobe | 1976 |
Clorazepate in epilepsy.
Topics: Anti-Anxiety Agents; Behavior; Clorazepate Dipotassium; Drug Interactions; Epilepsy, Temporal Lobe; | 1977 |
[Clinical significance of serum phenytoin level].
Topics: Adult; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Epileps | 1978 |
[Clinical study of serum level of dipropylacetic acid sodium (Depakene) by gaschromatography (author's transl)].
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Gas; Drug Therapy, Combination; Epilepsi | 1977 |
Carbamazepine levels in pregnancy and lactation.
Topics: Adult; Carbamazepine; Epilepsy, Temporal Lobe; Female; Fetal Blood; Fetus; Humans; Lactation; Milk, | 1979 |
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy | 1975 |
Seizures in adolescents.
Topics: Adolescent; Anticonvulsants; Automobile Driving; Benzodiazepines; Carbamazepine; Diagnosis, Differen | 1975 |
Sensible prescribing. XI.--Juvenile and adult epilepsy.
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Clonazepam; Epilepsy; Epilepsy, Absence; Epile | 1975 |
A comparison of the effectiveness of primidone versus carbamazepine in epileptic outpatients.
Topics: Adolescent; Adult; Carbamazepine; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; M | 1976 |
[Epileptic seizures with psychomotor symptoms and generalized spike-wave-pattern].
Topics: Adolescent; Adult; Carbamazepine; Child; Diagnosis, Differential; Drug Therapy, Combination; Electro | 1976 |
Epilepsy and other seizure disorders in children: drug management.
Topics: Acetazolamide; Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, T | 1976 |
Surgery of temporal lobe epilepsy.
Topics: Adolescent; Adult; Astrocytes; Brain Neoplasms; Cerebral Cortex; Child; Child, Preschool; Electroenc | 1975 |
Kinetic properties of hexokinase in resected temporal lobes of patients with drug-resistant epilepsy.
Topics: Age Factors; Cytoplasm; Epilepsy, Temporal Lobe; Female; Hexokinase; Humans; Kinetics; Male; Phenyto | 1975 |
Management of the difficult patient with complex partial seizures.
Topics: Adult; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epileps | 1975 |
Acute primidone overdosage with massive crystalluria.
Topics: Child; Chromatography, Gas; Crystallization; Epilepsy, Temporal Lobe; Female; Humans; Phenobarbital; | 1975 |
Brain concentrations of phenytoin, phenobarbitone and primidone in epileptic patients.
Topics: Adolescent; Adult; Brain Chemistry; Child; Child, Preschool; Chromatography, Gas; Epilepsy, Temporal | 1975 |
The toxic effects of anticonvulsant drugs in long-term treatment of epilepsy.
Topics: Anticonvulsants; Epilepsy, Temporal Lobe; Female; Humans; Middle Aged; Phenytoin; Primidone | 1989 |
Carbamazepine, phenytoin and phenobarbital in drug-resistant partial epilepsies.
Topics: Adolescent; Adult; Carbamazepine; Drug Evaluation; Drug Resistance; Epilepsies, Partial; Epilepsy, T | 1986 |
Ictal panic/epileptogenic activity: treatment with primidone.
Topics: Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; Fear; Female; Humans; Middle Age | 1988 |
Primidone-carbamazepine interaction: clinical consequences.
Topics: Adolescent; Carbamazepine; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Epilepsy, | 1987 |
[Side effects of anticonvulsants on the peripheral nervous system and vestibulo-ocular functions].
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; | 1985 |
Epilepsy.
Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effec | 1974 |
Connective tissue disease following anti-epileptic therapy.
Topics: Adult; Anticonvulsants; Child; Collagen Diseases; Electroencephalography; Epilepsy, Absence; Epileps | 1969 |
Dipropylacetate (Dépakine, Ergenyl) in the treatment of epilepsy.
Topics: Adolescent; Anticonvulsants; Barbiturates; Child; Child, Preschool; Drug Synergism; Electroencephalo | 1973 |
The pattern of epilepsy in Uganda.
Topics: Adolescent; Adult; Age Factors; Black People; Child; Child, Preschool; Electroencephalography; Epile | 1973 |
Psychomotor epilepsy in childhood.
Topics: Bromides; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; E | 1974 |
Clonazepam in the treatment of epilepsy.
Topics: Adult; Anticonvulsants; Benzodiazepinones; Chlorobenzenes; Chromatography, Gas; Drug Interactions; E | 1974 |
Clinical experience with sulthiame (Ospolot).
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Epilepsy, Temporal Lobe; Female; Humans; | 1966 |
Epilepsy.
Topics: Adult; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, T | 1969 |
Drug treatment of epilepsy in childhood.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Absence; Epil | 1969 |
[Therapy of epilepsy. The causes and consequences of inadequate treatment].
Topics: Acridines; Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Barbiturates; Carbamazepine; Child | 1972 |
Status epilepticus partialis wit fear as clinical expression. Report of a case and ictal EEG findings.
Topics: Adult; Amygdala; Anxiety Disorders; Electroencephalography; Epilepsy, Temporal Lobe; Fear; Female; H | 1973 |
Variation in response to anticonvulsants in a group of epileptic patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Chromatography, Gas; Epilepsy, Temporal Lobe; Epilepsy, To | 1972 |
Phenylethylmalonamide (PEMA). An important metabolite of primidone.
Topics: Adult; Amides; Animals; Blood Proteins; Chromatography, Gas; Epilepsy, Temporal Lobe; Epilepsy, Toni | 1972 |
Metabolic disposition of primidone and its metabolites in epileptic subjects after single and repeated administration.
Topics: Amides; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Primidone | 1972 |
Clinical and physiological effects of stimulation of the paleocerebellum in humans.
Topics: Adult; Cerebellum; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy; Ep | 1973 |
Human brain, cerebrospinal fluid, and plasma concentrations of diphenylhydantoin and phenobarbital.
Topics: Adolescent; Adult; Brain Chemistry; Child, Preschool; Chromatography, Gas; Epilepsy, Temporal Lobe; | 1974 |
Epilepsy in Iceland. A clinical and epidemiological investigation.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Automobile Driving; Child; Child, Preschool; Epilepsy, Abs | 1966 |
[Treatment of epilepsy in children].
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epil | 1967 |
[On the combination treatment of epileptic attacks].
Topics: Anticonvulsants; Drug Synergism; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Ton | 1968 |
[Results of treatment of epilepsy in children up to 14 years of age].
Topics: Adolescent; Age Factors; Barbiturates; Child; Child, Preschool; Diazepam; Drug Synergism; Electroenc | 1971 |
Temporal lobe seizures.
Topics: Epilepsy, Temporal Lobe; Humans; Primidone | 1972 |
Variation in response to anticonvulsants in a group of epileptic patients.
Topics: Epilepsy, Temporal Lobe; Female; Humans; Male; Mental Disorders; Phenobarbital; Phenytoin; Primidone | 1971 |
[Tactics in the medical treatment of temporal lobe epilepsy patients in the early and late period following surgery].
Topics: Adolescent; Adult; Anticonvulsants; Barbiturates; Child; Child, Preschool; Epilepsy, Temporal Lobe; | 1971 |