primidone has been researched along with Depressive Disorder, Major in 2 studies
Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
Excerpt | Relevance | Reference |
---|---|---|
"A 74 year old man presented to the Old Age Psychiatry Service with cognitive deficits while being treated for recurrent depressive episodes and essential tremor with Venlafaxine, Lithium, and Primidone." | 3.81 | Drug-induced cerebral glucose metabolism resembling Alzheimer's Disease: a case study. ( Beer, AJ; Riepe, MW; Vonend, C; Walther, B, 2015) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Riepe, MW | 1 |
Walther, B | 1 |
Vonend, C | 1 |
Beer, AJ | 1 |
Gaynes, BN | 1 |
Warden, D | 1 |
Trivedi, MH | 1 |
Wisniewski, SR | 1 |
Fava, M | 1 |
Rush, AJ | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder[NCT03748446] | Early Phase 1 | 20 participants (Anticipated) | Interventional | 2019-12-05 | Recruiting | ||
Subanesthetic Sevoflurane for Treatment-Resistant Depression: A Proof-of-Concept Trial[NCT05008939] | 15 participants (Anticipated) | Interventional | 2021-08-31 | Not yet recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 trial available for primidone and Depressive Disorder, Major
Article | Year |
---|---|
What did STAR*D teach us? Results from a large-scale, practical, clinical trial for patients with depression.
Topics: Adolescent; Adult; Aged; Bupropion; Citalopram; Cognitive Behavioral Therapy; Cyclohexanols; Depress | 2009 |
What did STAR*D teach us? Results from a large-scale, practical, clinical trial for patients with depression.
Topics: Adolescent; Adult; Aged; Bupropion; Citalopram; Cognitive Behavioral Therapy; Cyclohexanols; Depress | 2009 |
What did STAR*D teach us? Results from a large-scale, practical, clinical trial for patients with depression.
Topics: Adolescent; Adult; Aged; Bupropion; Citalopram; Cognitive Behavioral Therapy; Cyclohexanols; Depress | 2009 |
What did STAR*D teach us? Results from a large-scale, practical, clinical trial for patients with depression.
Topics: Adolescent; Adult; Aged; Bupropion; Citalopram; Cognitive Behavioral Therapy; Cyclohexanols; Depress | 2009 |
1 other study available for primidone and Depressive Disorder, Major
Article | Year |
---|---|
Drug-induced cerebral glucose metabolism resembling Alzheimer's Disease: a case study.
Topics: Aged; Alzheimer Disease; Anticonvulsants; Antidepressive Agents; Attention; Cognition Disorders; Dep | 2015 |