Page last updated: 2024-11-03

primidone and Cleft Palate

primidone has been researched along with Cleft Palate in 9 studies

Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.

Cleft Palate: Congenital fissure of the soft and/or hard palate, due to faulty fusion.

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Friis, ML	1
McElhatton, PR	2
Sullivan, FM	2
Toseland, PA	1
Biale, Y	1
Lewenthal, H	1
Aderet, NB	1
Annegers, JF	2
Elveback, LR	2
Hauser, WA	2
Kurland, LT	2
Lowe, CR	1
Meyer, JG	1
Elshove, J	1
van Eck, JH	1

Other Studies

9 other studies available for primidone and Cleft Palate

Article	Year
Epilepsy among parents of children with facial clefts. Epilepsia, 1979, Volume: 20, Issue:1 Topics: Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Humans; Male; Parents; Phenobarbital; Ph	1979
Teratogenic activity and metabolism of primidone in the mouse. Epilepsia, 1977, Volume: 18, Issue:1 Topics: Animals; Cleft Palate; Dose-Response Relationship, Drug; Female; Fetus; Mice; Palate; Pregnancy; Pri	1977
Teratogenic activity of the antiepileptic drugs phenobarbital, phenytoin, and primidone in mice. Toxicology and applied pharmacology, 1975, Volume: 34, Issue:2 Topics: Animals; Cleft Palate; Drug Interactions; Female; Gestational Age; Leucovorin; Maternal-Fetal Exchan	1975
Congenital malformations due to anticonvulsive drugs. Obstetrics and gynecology, 1975, Volume: 45, Issue:4 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anencephaly; Anticonvulsants; Birth Ord	1975
Epilepsy anticonvulsants and malformations. Birth defects original article series, 1975, Volume: 11, Issue:5 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Heart Defec	1975
Congenital malformations among infants born to epileptic women. Lancet (London, England), 1973, Jan-06, Volume: 1, Issue:7793 Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Congenital Abnormalities; England; Epilepsy; F	1973
Do anticonvulsants have a teratogenic effect? Archives of neurology, 1974, Volume: 31, Issue:6 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child, Preschool; Cleft Lip; Cleft Palate; Congenital	1974
The teratological effects of anticonvulsants and the effects on pregnancy and birth. European neurology, 1973, Volume: 10, Issue:3 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cleft Lip; Cleft Palate; Cyclohe	1973
[Congenital abnormalities, cleft lip and cleft palate in particular, in children of epileptic mothers]. Nederlands tijdschrift voor geneeskunde, 1971, Aug-14, Volume: 115, Issue:33 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Cleft Lip; Cleft Palate; Epilepsy; Fema	1971