Page last updated: 2024-11-03

primidone and Brain Disorders

primidone has been researched along with Brain Disorders in 10 studies

Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.

Research Excerpts

ExcerptRelevanceReference
"Experimental production of hemifacial microsomia by a folic acid antagonist, triaxene, is mediated via hemorrhage in the fetus."1.27Goldenhar syndrome, anterior encephalocele, and aqueductal stenosis following fetal primidone exposure. ( Chen, H; Gustavson, EE, 1985)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ANAND, MP1
Hawkins, DB1
Katano, H1
Fukushima, T1
Karasawa, K1
Sugiyama, N1
Ohkura, A1
Kamiya, K1
Botez, MI1
Peyronnard, JM1
Bérubé, L1
Labrecque, R1
Gustavson, EE1
Chen, H1
Cavazzuti, GB1
Bower, BD1
Garrettson, LK1
Perel, JM1
Dayton, PG1
Wålinder, J1

Trials

1 trial available for primidone and Brain Disorders

ArticleYear
The role of data audits in detecting scientific misconduct.
    JAMA, 1990, Jul-04, Volume: 264, Issue:1

    Topics: Anticonvulsants; Biomedical Research; Brain Diseases; Child; Clinical Trials as Topic; Drug Evaluati

1990

Other Studies

9 other studies available for primidone and Brain Disorders

ArticleYear
IATROGENIC MEGALOBLASTIC ANAEMIA WITH NEUROLOGICAL COMPLICATIONS.
    Scottish medical journal, 1964, Volume: 9

    Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Brain Diseases; Cysticercosis; Drug Therapy; Epil

1964
The effect of medication on interaural time and intensity discrimination in a hemispherectomee.
    Journal of speech and hearing research, 1980, Volume: 23, Issue:1

    Topics: Adult; Brain; Brain Diseases; Female; Humans; Loudness Perception; Phenytoin; Primidone

1980
Primidone-induced hyperammonemic encephalopathy in a patient with cerebral astrocytoma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2002, Volume: 9, Issue:1

    Topics: Anticonvulsants; Astrocytoma; Brain Diseases; Brain Neoplasms; Electroencephalography; Female; Human

2002
Relapsing neuropathy, cerebral atrophy and folate deficiency. A close association.
    Applied neurophysiology, 1979, Volume: 42, Issue:3

    Topics: Atrophy; Brain Diseases; Edema; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Intesti

1979
Goldenhar syndrome, anterior encephalocele, and aqueductal stenosis following fetal primidone exposure.
    Teratology, 1985, Volume: 32, Issue:1

    Topics: Adult; Brain Diseases; Cerebral Aqueduct; Constriction, Pathologic; Encephalocele; Epilepsy; Female;

1985
[Considerations and research on febrile convulsions].
    Minerva pediatrica, 1974, Apr-14, Volume: 26, Issue:13

    Topics: Anticonvulsants; Brain Diseases; Child, Preschool; Diagnosis, Differential; Diazepam; Electroencepha

1974
Minor epileptic status.
    Developmental medicine and child neurology, 1972, Volume: 14, Issue:1

    Topics: Brain Diseases; Child; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Phenytoin; Primidone

1972
Methylphenidate interaction with both anticonvulsants and ethyl biscoumacetate.
    JAMA, 1969, Mar-17, Volume: 207, Issue:11

    Topics: Adult; Anticonvulsants; Ataxia; Brain Diseases; Child, Preschool; Depression, Chemical; Ethyl Biscou

1969
Transvestism, definition and evidence in favor of occasional derivation from cerebral dysfunction.
    International journal of neuropsychiatry, 1965, Volume: 1, Issue:6

    Topics: Adult; Anticonvulsants; Brain Diseases; Brain Injuries; Electroencephalography; Humans; Male; Primid

1965