Page last updated: 2024-11-03

primidone and Allergy, Drug

primidone has been researched along with Allergy, Drug in 8 studies

Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.

Research Excerpts

ExcerptRelevanceReference
"The antiepileptic drug hypersensitivity syndrome (AHS) is an adverse drug reaction associated with the aromatic antiepileptic drugs (AEDs) phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), and primidone."4.80Antiepileptic drug hypersensitivity syndrome. ( Schlienger, RG; Shear, NH, 1998)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GOLDSTEIN, N1
LEIDER, M1
BAER, RL1
Handfield-Jones, SE1
Jenkins, RE1
Whittaker, SJ1
Besse, CP1
McGibbon, DH1
Schlienger, RG1
Shear, NH1
Parsonage, M1
Skrotskiĭ, IuA1
Booker, HE1
Chun, RW1
Sanguino, M1
Harms, D1
Schreiber, MM1
McGregor, JG1

Reviews

1 review available for primidone and Allergy, Drug

ArticleYear
Antiepileptic drug hypersensitivity syndrome.
    Epilepsia, 1998, Volume: 39 Suppl 7

    Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; Diagnosis, Differential; D

1998

Other Studies

7 other studies available for primidone and Allergy, Drug

ArticleYear
Drug eruptions from anticonvulsant drugs. Observations on drug-induced lesions that were fixed and lupus-erythematosus-like, and on cross-reactivity between several drugs involved.
    Archives of dermatology, 1963, Volume: 87

    Topics: Anticonvulsants; Barbiturates; Drug Eruptions; Drug Hypersensitivity; Humans; Phenytoin; Primidone

1963
The anticonvulsant hypersensitivity syndrome.
    The British journal of dermatology, 1993, Volume: 129, Issue:2

    Topics: Adult; Anticonvulsants; Bronchial Diseases; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Fa

1993
Epilepsy.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effec

1974
[Complications of medical therapy for epilepsy in children and adolescents].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1973, Volume: 73, Issue:11

    Topics: Anticonvulsants; Child; Diplopia; Drug Hypersensitivity; Drug Therapy, Combination; Epilepsy; Headac

1973
Myasthenia gravis syndrome associated with trimethadione.
    JAMA, 1970, Jun-29, Volume: 212, Issue:13

    Topics: Anticonvulsants; Autoimmune Diseases; Child; Drug Hypersensitivity; Epilepsy, Absence; Female; Human

1970
[Speech disorders in children with cerebral convulsions].
    Klinische Padiatrie, 1972, Volume: 184, Issue:1

    Topics: Adolescent; Barbiturates; Carbamazepine; Drug Hypersensitivity; Electroencephalography; Epilepsy; Et

1972
Pseudolymphoma syndrome. A sensitivity to anticonvulsant drugs.
    Archives of dermatology, 1968, Volume: 97, Issue:3

    Topics: Biopsy; Blood Cell Count; Blood Chemical Analysis; Chlordiazepoxide; Drug Hypersensitivity; Female;

1968