primidone has been researched along with Adult Rickets in 17 studies
Primidone: A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
primidone : A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The investigation and treatment of osteomalacia are described in four patients with epilepsy treated with long-term anticonvulsant therapy." | 1.25 | Osteomalacia with long-term anticonvulsant therapy in epilepsy. ( Dent, CE; Richens, A; Rowe, DJ; Stamp, TC, 1970) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (94.12) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Radó, JP | 1 |
| Haris, A | 1 |
| Dymling, JF | 1 |
| Lidgren, L | 1 |
| Wallöe, A | 1 |
| Mehregan, U | 1 |
| Krause, KH | 1 |
| Prager, P | 1 |
| Maclay, E | 1 |
| Hadden, DR | 1 |
| McIlrath, EM | 1 |
| Nesbitt, GS | 1 |
| Lehmann, V | 1 |
| Aarli, J | 1 |
| Schreiner, A | 1 |
| Ashworth, B | 1 |
| Horn, DB | 1 |
| Wilczek, H | 1 |
| Pacovský, V | 1 |
| Hazuková, L | 1 |
| Kalvach, Z | 1 |
| Sisková, M | 1 |
| Lücking, T | 1 |
| Delling, G | 1 |
| Livingston, S | 1 |
| Pauli, LL | 1 |
| Bowden, AN | 1 |
| Flury, W | 1 |
| Slomic, A | 1 |
| Szöts, F | 1 |
| Christiansen, C | 1 |
| Rodbro, P | 1 |
| Lund, M | 1 |
| Borgstedt, AD | 1 |
| Bryson, MF | 1 |
| Young, LW | 1 |
| Forbes, GB | 1 |
| Genuth, SM | 1 |
| Klein, L | 1 |
| Rabinovich, S | 1 |
| King, KC | 1 |
| Linde, J | 1 |
| Molholm Hansen, J | 1 |
| Siersbaek-Nielsen, K | 1 |
| Fuglsang-Fredriksen, V | 1 |
| Dent, CE | 1 |
| Richens, A | 1 |
| Rowe, DJ | 1 |
| Stamp, TC | 1 |
1 review available for primidone and Adult Rickets
| Article | Year |
|---|---|
Osteomalacia and anticonvulsant drugs.
Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Epilepsy; Folic Acid; Humans; Liver; Osteomalacia; P | 1971 |
1 trial available for primidone and Adult Rickets
| Article | Year |
|---|---|
Incidence of anticonvulsant osteomalacia and effect of vitamin D: controlled therapeutic trial.
Topics: Adult; Aged; Alkaline Phosphatase; Anticonvulsants; Bone and Bones; Calcium; Creatinine; Epilepsy; F | 1973 |
15 other studies available for primidone and Adult Rickets
| Article | Year |
|---|---|
Metabolic bone disease (anticonvulsant osteomalacia) and renal tubular acidosis in tuberous sclerosis.
Topics: Acidosis, Renal Tubular; Adult; Back Pain; Bicarbonates; Bone and Bones; Calcitriol; Calcium; Calciu | 1993 |
Biochemical variables related to calcium metabolism in epileptics.
Topics: Aged; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilepsy; Female; Humans; Male; | 1979 |
[The frequency of adult anticonvulsant osteomalacia in relation to duration of therapy and dosage of anticonvulsants (author's transl)].
Topics: Adult; Alkaline Phosphatase; Calcium; Dose-Response Relationship, Drug; Drug Therapy, Combination; E | 1979 |
Hypocalcaemia and secondary hyperparathyroidism in institutionalised mentally-retarded patients receiving anticonvulsant drugs: a survey of 292 patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Female; Humans; Hydroxycholecalci | 1978 |
[Hypocalcemia and tetany induced by antiepileptic treatment].
Topics: Adolescent; Epilepsy; Humans; Hypocalcemia; Male; Osteomalacia; Primidone; Tetany; Time Factors | 1977 |
Evidence of osteomalacia in an outpatient group of adult epileptics.
Topics: Adult; Aged; Diet; Epilepsy; Female; Humans; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenyto | 1977 |
[Treatment of osteomalacia caused by anticonvulsants with a derivative of vitamin D (case report)].
Topics: Dihydrotachysterol; Female; Humans; Middle Aged; Osteomalacia; Primidone | 1986 |
[Severe rachitic osteopathy during long-term anticonvulsant treatment].
Topics: Administration, Oral; Alkaline Phosphatase; Anticonvulsants; Biopsy; Calcium; Carbamazepine; Child; | 1973 |
Letter: Anticonvulsants and vitamin D metabolism.
Topics: Child; Drug Therapy, Combination; Epilepsy; Humans; Osteomalacia; Phenobarbital; Phenytoin; Primidon | 1974 |
[Osteomalacia due to a long-term antiepileptic treatment].
Topics: Anticonvulsants; Calcium; Female; Humans; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Primi | 1972 |
[Severe osteomalacic rickets induced by antiepileptic drugs. Literature review apropos of a case].
Topics: Child; Child, Preschool; Humans; Male; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Rickets; V | 1973 |
Long-term administration of antiepileptic drugs and the development of rickets.
Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Diazepam; Ethosuximide; Female; Gluconates; Humans; | 1972 |
Osteomalacia accompanying chronic anticonvulsant therapy.
Topics: Adolescent; Alkaline Phosphatase; Biopsy; Bone and Bones; Calcium; Epilepsy; Humans; Hydroxyproline; | 1972 |
Bone density in patients receiving long-term anticonvulsant therapy.
Topics: Absorptiometry, Photon; Adult; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilep | 1971 |
Osteomalacia with long-term anticonvulsant therapy in epilepsy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Biopsy; Calcium; Enzyme Induction; Epileps | 1970 |