Page last updated: 2024-11-03

primaquine and Tuberculosis, Multidrug-Resistant

primaquine has been researched along with Tuberculosis, Multidrug-Resistant in 1 studies

Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.

Tuberculosis, Multidrug-Resistant: Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Souza, MV1
Pais, KC1
Kaiser, CR1
Peralta, MA1
de L Ferreira, M1
Lourenço, MC1

Other Studies

1 other study available for primaquine and Tuberculosis, Multidrug-Resistant

ArticleYear
Synthesis and in vitro antitubercular activity of a series of quinoline derivatives.
    Bioorganic & medicinal chemistry, 2009, Feb-15, Volume: 17, Issue:4

    Topics: Antitubercular Agents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Quinolines; Structur

2009