primaquine has been researched along with Porphyrias in 7 studies
Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
RUMLER, W | 1 |
SANTAGOSTINI, F | 1 |
Thornsvard, CT | 1 |
Guider, BA | 1 |
Kimball, DB | 1 |
Lamy, M | 1 |
Scholnick, PL | 1 |
Epstein, J | 1 |
Marver, HS | 1 |
Gryglewski, R | 1 |
Kalmus, H | 1 |
1 review available for primaquine and Porphyrias
Article | Year |
---|---|
[Medical pharmacogenetics. I. Methods applied in pharmacogenetic studies].
Topics: Catecholamines; Genetics, Medical; Humans; Isoniazid; Methemoglobinemia; Methods; Pharmacogenetics; | 1967 |
6 other studies available for primaquine and Porphyrias
Article | Year |
---|---|
[ON PHARMACOGENETICS].
Topics: Abnormalities, Drug-Induced; Catalase; Enzyme Inhibitors; Glucosephosphate Dehydrogenase Deficiency; | 1963 |
[PHARMACOGENETICS].
Topics: Anemia; Anemia, Hemolytic; Barbiturates; Catalase; Cholinesterases; Genetics, Medical; Glucosephosph | 1964 |
An unusual reaction to chloroquine-primaquine.
Topics: Adult; Chloroquine; Coproporphyrins; Female; Humans; Malaria; Porphyrias; Primaquine; Uroporphyrins | 1976 |
[Pharmacogenetics].
Topics: Barbiturates; Female; Glucosephosphate Dehydrogenase Deficiency; Heterozygote; Humans; Isoniazid; Ma | 1972 |
The molecular basis of the action of chloroquine in porphyria cutanea tarda.
Topics: 5-Aminolevulinate Synthetase; Animals; Chemical Phenomena; Chemistry; Chloroquine; Chromatography, G | 1973 |
Scope and limitations of pharmacogenetics.
Topics: Animals; Barbiturates; Cholinesterases; Dextrans; Favism; Genes; Genetics; Genetics, Medical; Glucos | 1968 |