primaquine has been researched along with P carinii Pneumonia in 57 studies
Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Though these drugs are generally well tolerated, they can result in potentially severe adverse effects." | 5.56 | Murphy's law in force: sequential adverse events encountered during the treatment of Pneumocystis pneumonia (cotrimoxazole-induced acute peripheral neuropathy and primaquine-induced methemoglobinemia). ( Agarwal, R; Dhooria, S; Muthu, V; Prasad, KT; Saxena, P; Sehgal, IS, 2020) |
| "Hematotoxicity in individuals genetically deficient in glucose-6-phosphate dehydrogenase (G6PD) activity is the major limitation of primaquine (PQ), the only antimalarial drug in clinical use for treatment of relapsing Plasmodium vivax malaria." | 3.80 | Scalable preparation and differential pharmacologic and toxicologic profiles of primaquine enantiomers. ( Baresel, P; Bartlett, MS; Fronczek, FR; Gettayacamin, M; Herath, HM; McChesney, JD; Melendez, V; Nanayakkara, NP; Ohrt, C; Reichard, GA; Rochford, R; Sahu, R; Tekwani, BL; Tungtaeng, A; van Gessel, Y; Walker, LA; Wickham, KS, 2014) |
| "8-Aminoquinolines are an important class of antiparasitic agents, with broad utility and excellent efficacy, but also limitations due to hematological toxicities, primarily methemoglobinemia and hemolysis." | 3.74 | Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline succinate. ( Ager, AL; Bartlett, MS; Croft, SL; Khan, IA; McChesney, JD; Nanayakkara, NP; Walker, LA; Yardley, V, 2008) |
| "Mild to moderately severe Pneumocystis carinii pneumonia in patients with AIDS was treated in a clinical trial with a combination regimen of primaquine and clindamycin, and the efficacy of this regimen was compared with that of the conventional treatment regimen of trimethoprim/sulfamethoxazole." | 2.67 | Efficacy of clindamycin/primaquine versus trimethoprim/sulfamethoxazole in primary treatment of Pneumocystis carinii pneumonia. ( Pohle, HD; Rohde, I; Ruf, B, 1991) |
| "The primaquine group had lower 90-day mortality rate (45." | 1.72 | Prognostic factors and clinical efficacy of second-line treatments of Pneumocystis jirovecii pneumonia for non-HIV patients after first-line treatment failure. ( Cao, G; Liu, A; Liu, X; Sun, R; Yang, J; Zhu, H, 2022) |
| "Primaquine was not nationally licensed at the time but imported by RG-CTD for the use in a clinical research to investigate safety and efficacy in malaria treatment." | 1.62 | Primaquine plus clindamycin as a promising salvage therapy for Pneumocystis jirovecii pneumonia: A retrospective analysis in Japanese patients. ( Kato, Y; Kikuchi, T; Kimura, M; Kobayashi, I; Koga, M; Maruyama, H; Shoji, K; Suganuma, A; Takezaki, S; Yoshimura, Y, 2021) |
| " Though these drugs are generally well tolerated, they can result in potentially severe adverse effects." | 1.56 | Murphy's law in force: sequential adverse events encountered during the treatment of Pneumocystis pneumonia (cotrimoxazole-induced acute peripheral neuropathy and primaquine-induced methemoglobinemia). ( Agarwal, R; Dhooria, S; Muthu, V; Prasad, KT; Saxena, P; Sehgal, IS, 2020) |
| "Vitamin D-mediated hypercalcemia is an uncommon complication of Pneumocystis infection." | 1.51 | A case of Pneumocystis pneumonia, with a granulomatous response and vitamin D-mediated hypercalcemia, presenting 13 years after renal transplantation. ( Aesif, SW; Matson, KM; Taylor, LN, 2019) |
| " We also found that ATRA in combination with primaquine was as effective as the combination of trimethoprim and sulfamethaxazole for treatment of PcP and completely eliminated MDSCs and Pc organisms in the lungs in two weeks." | 1.39 | All-trans retinoic acid in combination with primaquine clears pneumocystis infection. ( Durant, PJ; Jung, HW; Lee, CH; Lei, GS; Shao, S; Zhang, C, 2013) |
| "Pentamidine was associated with a greater risk of death when used as first- and second-line therapy for HIV-associated PCP, and was associated with more treatment changes." | 1.35 | Clinical efficacy of first- and second-line treatments for HIV-associated Pneumocystis jirovecii pneumonia: a tri-centre cohort study. ( Atzori, C; Benfield, T; Helweg-Larsen, J; Miller, RF, 2009) |
| "Pneumocystis pneumonia is an increasingly recognized threat in non-HIV immunosuppressed patients and is associated with worse outcomes compared to HIV-infected patients." | 1.35 | Successful treatment of severe pneumocystis pneumonia with clindamycin-primaquine in an HIV-negative patient. ( Blatz, PJ; Crisp, HC; Okulicz, JF; Rice, DH; Stewart, IJ, 2009) |
| "Pneumocystis carinii pneumonia has been the most common life-threatening opportunistic infection in patients with acquired immunodeficiency syndrome." | 1.29 | Dilemmas in the prophylaxis of Pneumocystis carinii pneumonia. ( Glatt, AE, 1994) |
| " These studies suggest that higher doses of 8-aminoquinolines administered at appropriate intervals may be as effective as continuous dosing for prophylaxis of P." | 1.28 | Efficacy of intermittent dosage of 8-aminoquinolines for therapy or prophylaxis of Pneumocystis pneumonia in rats. ( Bartlett, MS; Berman, JD; Dean, RA; Ellis, WY; Milhous, WK; Queener, SF; Smith, JW, 1992) |
| "Primaquine (30 mg) was given orally to all patients except three; two of these patients received 15 mg of the drug daily and another 30 mg of drug on alternate days." | 1.28 | Salvage therapy with clindamycin/primaquine for Pneumocystis carinii pneumonia. ( Black, JR; Murphy, RL; Noskin, GA; Phair, JP, 1992) |
| "57 mg/kg, showing activity greater than that of primaquine at this dosage and comparable to that of trimethoprim-sulfamethoxazole at 50/250 mg/kg." | 1.28 | 8-Aminoquinolines from Walter Reed Army Institute for Research for treatment and prophylaxis of Pneumocystis pneumonia in rat models. ( Bartlett, MS; Berman, JD; Ellis, WY; Milhous, WK; Queener, SF; Smith, JW; Tidwell, RR, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (8.77) | 18.7374 |
| 1990's | 27 (47.37) | 18.2507 |
| 2000's | 13 (22.81) | 29.6817 |
| 2010's | 8 (14.04) | 24.3611 |
| 2020's | 4 (7.02) | 2.80 |
| Authors | Studies |
|---|---|
| Queener, SF | 4 |
| Nanayakkara, NP | 2 |
| Ager, AL | 1 |
| Bartlett, MS | 5 |
| Yardley, V | 1 |
| Croft, SL | 1 |
| Khan, IA | 1 |
| McChesney, JD | 2 |
| Walker, LA | 2 |
| Liu, A | 1 |
| Sun, R | 1 |
| Cao, G | 1 |
| Liu, X | 1 |
| Zhu, H | 1 |
| Yang, J | 1 |
| Saxena, P | 1 |
| Muthu, V | 1 |
| Dhooria, S | 1 |
| Sehgal, IS | 1 |
| Prasad, KT | 1 |
| Agarwal, R | 1 |
| Sahu, KK | 1 |
| Mishra, AK | 1 |
| Lal, A | 1 |
| Siddiqui, AD | 1 |
| George, SV | 1 |
| Koga, M | 1 |
| Suganuma, A | 1 |
| Kikuchi, T | 1 |
| Yoshimura, Y | 2 |
| Shoji, K | 1 |
| Kobayashi, I | 1 |
| Takezaki, S | 1 |
| Kato, Y | 1 |
| Kimura, M | 1 |
| Maruyama, H | 1 |
| Wang, X | 1 |
| Wang, GF | 1 |
| Jin, Z | 1 |
| Huang, JJ | 1 |
| Mu, XD | 1 |
| Zhang, W | 1 |
| Taylor, LN | 1 |
| Aesif, SW | 1 |
| Matson, KM | 1 |
| Tekwani, BL | 1 |
| Herath, HM | 1 |
| Sahu, R | 1 |
| Gettayacamin, M | 1 |
| Tungtaeng, A | 1 |
| van Gessel, Y | 1 |
| Baresel, P | 1 |
| Wickham, KS | 1 |
| Fronczek, FR | 1 |
| Melendez, V | 1 |
| Ohrt, C | 1 |
| Reichard, GA | 1 |
| Rochford, R | 1 |
| Nickel, P | 1 |
| Schürmann, M | 1 |
| Albrecht, H | 1 |
| Schindler, R | 1 |
| Budde, K | 1 |
| Westhoff, T | 1 |
| Millward, J | 1 |
| Suttorp, N | 1 |
| Reinke, P | 1 |
| Schürmann, D | 1 |
| Sakamoto, Y | 1 |
| Amano, Y | 1 |
| Tachikawa, N | 1 |
| Lei, GS | 2 |
| Zhang, C | 2 |
| Zimmerman, MK | 1 |
| Lee, CH | 2 |
| Maschmeyer, G | 1 |
| Helweg-Larsen, J | 3 |
| Pagano, L | 1 |
| Robin, C | 1 |
| Cordonnier, C | 1 |
| Schellongowski, P | 1 |
| Kim, T | 1 |
| Kim, SH | 1 |
| Park, KH | 1 |
| Cho, OH | 1 |
| Sung, H | 1 |
| Kim, MN | 1 |
| Choi, SH | 1 |
| Jeong, JY | 1 |
| Woo, JH | 1 |
| Kim, YS | 1 |
| Lee, SO | 1 |
| Benfield, T | 2 |
| Atzori, C | 2 |
| Miller, RF | 3 |
| Crisp, HC | 1 |
| Stewart, IJ | 1 |
| Blatz, PJ | 1 |
| Rice, DH | 1 |
| Okulicz, JF | 1 |
| Oliver, M | 1 |
| Wolf, A | 1 |
| Théfenne, H | 1 |
| Demaison, X | 1 |
| Rapp, C | 2 |
| Simon, F | 1 |
| Shao, S | 1 |
| Jung, HW | 1 |
| Durant, PJ | 1 |
| VIALATTE, J | 1 |
| PAUPE, J | 1 |
| MEYER, B | 1 |
| Bellamy, R | 3 |
| Leclercq, P | 1 |
| Betz, R | 1 |
| Lambermont, B | 1 |
| Leonard, P | 1 |
| Frippiat, F | 1 |
| Mitchell, B | 1 |
| Hamill, M | 1 |
| Harte, D | 1 |
| von Sonnenburg, F | 1 |
| Prüfer, L | 1 |
| Pastor, C | 1 |
| Lumbreras, C | 1 |
| Lizasoain, M | 1 |
| Garcés, JL | 1 |
| Arrizabalaga, J | 1 |
| Iribarren, JA | 1 |
| Rodríguez, F | 1 |
| Garde, C | 1 |
| García, A | 1 |
| Black, JR | 4 |
| Feinberg, J | 3 |
| Murphy, RL | 3 |
| Fass, RJ | 2 |
| Finkelstein, D | 1 |
| Akil, B | 1 |
| Safrin, S | 2 |
| Carey, JT | 1 |
| Stansell, J | 1 |
| Plouffe, JF | 1 |
| Glatt, AE | 1 |
| Smith, N | 1 |
| Blanshard, C | 1 |
| Smith, D | 1 |
| Gazzard, B | 1 |
| Toma, E | 4 |
| Fournier, S | 2 |
| Dumont, M | 1 |
| Bolduc, P | 1 |
| Deschamps, H | 1 |
| Zouiten, F | 1 |
| Bouslama, K | 1 |
| Gastli, M | 1 |
| Tiouiri, H | 1 |
| Battikh, R | 1 |
| Ben Salem, N | 1 |
| Ben Chaabane, T | 1 |
| Chaker, E | 1 |
| Ben Rachid, MS | 1 |
| Zribi, A | 1 |
| Goebel, FD | 1 |
| Bogner, JR | 1 |
| Korraa, H | 1 |
| Saadeh, C | 1 |
| Finkelstein, DM | 1 |
| Frame, P | 1 |
| Simpson, G | 1 |
| Wu, A | 1 |
| Cheung, T | 1 |
| Soeiro, R | 1 |
| Hojczyk, P | 1 |
| Sin, DD | 1 |
| Shafran, SD | 1 |
| Barber, BA | 1 |
| Pegram, PS | 1 |
| High, KP | 1 |
| Deresinski, SC | 1 |
| Morris-Jones, SD | 1 |
| Easterbrook, PJ | 1 |
| Thorne, A | 1 |
| Singer, J | 1 |
| Raboud, J | 1 |
| Lemieux, C | 1 |
| Trottier, S | 1 |
| Bergeron, MG | 1 |
| Tsoukas, C | 1 |
| Falutz, J | 1 |
| Lalonde, R | 1 |
| Gaudreau, C | 1 |
| Therrien, R | 1 |
| Nicolas, X | 1 |
| Bohand, X | 1 |
| Masur, H | 1 |
| Kantor, GS | 1 |
| Vildé, JL | 1 |
| Remington, JS | 1 |
| Dean, RA | 1 |
| Milhous, WK | 2 |
| Berman, JD | 2 |
| Ellis, WY | 2 |
| Smith, JW | 3 |
| Noskin, GA | 1 |
| Phair, JP | 1 |
| Tidwell, RR | 1 |
| Carey, J | 1 |
| Sattler, FR | 1 |
| Ruf, B | 2 |
| Rohde, I | 1 |
| Pohle, HD | 2 |
| Kay, R | 1 |
| DuBois, RE | 1 |
| Poisson, M | 1 |
| Morisset, R | 1 |
| Phaneuf, D | 1 |
| Vega, C | 1 |
| Richardson, JD | 1 |
| Durkin, MM | 1 |
| Jay, MA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Development of Safer Drugs for Malaria in U.S. Troops, Civilian Personnel, and Travelers: Clinical Evaluation of Primaquine Enantiomer[NCT02898779] | Phase 1 | 36 participants (Actual) | Interventional | 2017-05-01 | Completed | ||
| The Safety and Efficacy of Clindamycin and Primaquine in the Treatment of Mild - Moderate Pneumocystis Carinii Pneumonia in Patients With AIDS[NCT00000717] | 50 participants | Interventional | Completed | ||||
| A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Trimethoprim / Sulfamethoxazole in the Treatment of Mild-to-Moderate PCP in Patients With AIDS[NCT00000640] | Phase 3 | 290 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 reviews available for primaquine and P carinii Pneumonia
| Article | Year |
|---|---|
New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.
Topics: Animals; Drug Design; Humans; Immunosuppression Therapy; Molecular Structure; Opportunistic Infectio | 1995 |
Pneumocystis carinii pneumonia treatment in people infected with HIV.
Topics: Antifungal Agents; Atovaquone; Clindamycin; Dapsone; Drug Therapy, Combination; HIV Infections; Huma | 2004 |
Pneumocystis pneumonia in people with HIV.
Topics: Atovaquone; Clindamycin; Corticosterone; Dapsone; Drug Therapy, Combination; HIV Infections; Humans; | 2005 |
Pneumocystis pneumonia in people with HIV.
Topics: Anti-Infective Agents; Antiprotozoal Agents; Atovaquone; Clindamycin; Dapsone; Drug Therapy, Combina | 2006 |
A background and critical analysis of the treatment of pneumocystis carinii pneumonia (PCP) in HIV/AIDS.
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Anti-Inflammatory Agents; Antiprotozoa | 2007 |
Second-line salvage treatment of AIDS-associated Pneumocystis jirovecii pneumonia: a case series and systematic review.
Topics: AIDS-Related Opportunistic Infections; Clindamycin; Cohort Studies; Humans; Pentamidine; Pneumocysti | 2008 |
[Progress in immunodiagnosis and chemotherapy of protozoan infections].
Topics: Amebiasis; Animals; Antibodies; Babesiosis; Chloroquine; Drug Resistance, Microbial; Giardiasis; Hum | 1983 |
[Current alternatives in the treatment of Pneumocystis carinii pneumonia in patients with AIDS].
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Atovaquone; Clindamycin; Dapsone; Eflornit | 1994 |
[Therapy and prevention of pneumocystis carinii pneumonia].
Topics: AIDS-Related Opportunistic Infections; Animals; Antifungal Agents; Atovaquone; Clindamycin; Clinical | 1995 |
Options in the management of pneumonia caused by Pneumocystis carinii in patients with acquired immune deficiency syndrome and intolerance to trimethoprim/sulfamethoxazole.
Topics: Adrenal Cortex Hormones; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Ag | 1996 |
Treatment of Pneumocystis carinii pneumonia in adults with AIDS.
Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifunga | 1997 |
Current issues in the treatment and prophylaxis of Pneumocystis carinii pneumonia in HIV infection.
Topics: Adrenal Cortex Hormones; Adult; AIDS-Related Opportunistic Infections; Child; Clindamycin; Drug Ther | 1997 |
Prophylaxis and therapy for Pneumocystis pneumonia--where are we?
Topics: Adrenal Cortex Hormones; AIDS-Related Opportunistic Infections; Antifungal Agents; Atovaquone; Clind | 1992 |
9 trials available for primaquine and P carinii Pneumonia
| Article | Year |
|---|---|
[Clindamycin-primaquine in the treatment of Pneumocystis carinii pneumonia].
Topics: Adult; Clindamycin; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Male; Pentamidine; Pn | 1994 |
Clindamycin and primaquine therapy for mild-to-moderate episodes of Pneumocystis carinii pneumonia in patients with AIDS: AIDS Clinical Trials Group 044.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adolescent; Adult; AIDS-Related Opportunis | 1994 |
Clindamycin/primaquine versus trimethoprim-sulfamethoxazole as primary therapy for Pneumocystis carinii pneumonia in AIDS: a randomized, double-blind pilot trial.
Topics: Adult; AIDS-Related Opportunistic Infections; Clindamycin; Double-Blind Method; Drug Therapy, Combin | 1993 |
Comparison of three regimens for treatment of mild to moderate Pneumocystis carinii pneumonia in patients with AIDS. A double-blind, randomized, trial of oral trimethoprim-sulfamethoxazole, dapsone-trimethoprim, and clindamycin-primaquine. ACTG 108 Study
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Clindamycin; Dapsone; Double-Blind Met | 1996 |
Clindamycin with primaquine vs. Trimethoprim-sulfamethoxazole therapy for mild and moderately severe Pneumocystis carinii pneumonia in patients with AIDS: a multicenter, double-blind, randomized trial (CTN 004). CTN-PCP Study Group.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Clindamycin; Double-Blind Metho | 1998 |
Clindamycin and primaquine as primary treatment for mild and moderately severe Pneumocystis carinii pneumonia in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Clindamycin; Humans; Injections, Intraveno | 1991 |
Efficacy of clindamycin/primaquine versus trimethoprim/sulfamethoxazole in primary treatment of Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Adult; Clindamycin; Drug Therapy, Combination; Female; Humans; M | 1991 |
Clindamycin/primaquine for treatment of Pneumocystis carinii pneumonia in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Clindamycin; Drug Therapy, Combination; Humans; Pneumonia, Pneum | 1991 |
Clindamycin with primaquine for Pneumocystis carinii pneumonia.
Topics: Administration, Oral; Clindamycin; Clinical Trials as Topic; Drug Therapy, Combination; Follow-Up St | 1989 |
35 other studies available for primaquine and P carinii Pneumonia
| Article | Year |
|---|---|
Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline succinate.
Topics: Aminoquinolines; Animals; Antifungal Agents; Antiprotozoal Agents; Dogs; Female; Hemolysis; Humans; | 2008 |
Prognostic factors and clinical efficacy of second-line treatments of Pneumocystis jirovecii pneumonia for non-HIV patients after first-line treatment failure.
Topics: Bacteremia; Clindamycin; Coinfection; Cytomegalovirus Infections; Humans; Pneumocystis carinii; Pneu | 2022 |
Murphy's law in force: sequential adverse events encountered during the treatment of Pneumocystis pneumonia (cotrimoxazole-induced acute peripheral neuropathy and primaquine-induced methemoglobinemia).
Topics: Anti-Bacterial Agents; Antimalarials; Clindamycin; Dapsone; Drug Therapy, Combination; Female; Human | 2020 |
Methemoglobinemia: a challenge while managing pneumocystis jirovecii pneumonia.
Topics: Humans; Methemoglobinemia; New Zealand; Peripheral Nervous System Diseases; Pneumonia, Pneumocystis; | 2020 |
Primaquine plus clindamycin as a promising salvage therapy for Pneumocystis jirovecii pneumonia: A retrospective analysis in Japanese patients.
Topics: Adult; Clindamycin; Humans; Japan; Pneumocystis carinii; Pneumonia, Pneumocystis; Primaquine; Retros | 2021 |
[Efficacy of clindamycin-primaquine as the salvage treatment for pneumocystis pneumonia in non-HIV-infected patients].
Topics: Adult; Anti-Bacterial Agents; Clindamycin; Drug Therapy, Combination; HIV Infections; Humans; Middle | 2017 |
A case of Pneumocystis pneumonia, with a granulomatous response and vitamin D-mediated hypercalcemia, presenting 13 years after renal transplantation.
Topics: Acute Kidney Injury; Antifungal Agents; Clindamycin; Granuloma; Humans; Hypercalcemia; Kidney Transp | 2019 |
Scalable preparation and differential pharmacologic and toxicologic profiles of primaquine enantiomers.
Topics: Animals; Antimalarials; Dogs; Erythrocyte Transfusion; Erythrocytes; Female; Glucosephosphate Dehydr | 2014 |
Clindamycin-primaquine for pneumocystis jiroveci pneumonia in renal transplant patients.
Topics: Adult; Aged; Antifungal Agents; Clindamycin; Cohort Studies; Female; Humans; Kidney Transplantation; | 2014 |
[Case Report: Clindamycin with Primaquine Therapy for Severe Pneumocystis Pneumonia].
Topics: Anti-Bacterial Agents; Clindamycin; Drug Therapy, Combination; Female; Humans; Infusions, Intravenou | 2015 |
Vitamin D as Supplemental Therapy for Pneumocystis Pneumonia.
Topics: Albumins; Animals; Antifungal Agents; Calcium; CD11b Antigen; Cholecalciferol; Dietary Supplements; | 2015 |
ECIL guidelines for treatment of Pneumocystis jirovecii pneumonia in non-HIV-infected haematology patients.
Topics: Administration, Intravenous; Antifungal Agents; Clindamycin; Hematologic Neoplasms; Humans; Pneumocy | 2016 |
Clindamycin-primaquine versus pentamidine for the second-line treatment of pneumocystis pneumonia.
Topics: Adult; Aged; Anti-Infective Agents; Clindamycin; Female; Humans; Male; Middle Aged; Pentamidine; Pne | 2009 |
Clinical efficacy of first- and second-line treatments for HIV-associated Pneumocystis jirovecii pneumonia: a tri-centre cohort study.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; | 2009 |
Successful treatment of severe pneumocystis pneumonia with clindamycin-primaquine in an HIV-negative patient.
Topics: Aged; Antifungal Agents; Clindamycin; Drug Therapy, Combination; HIV Seronegativity; Humans; Male; P | 2009 |
[Update on primaquine].
Topics: Antimalarials; Chagas Disease; Humans; Malaria; Pneumonia, Pneumocystis; Primaquine | 2009 |
All-trans retinoic acid in combination with primaquine clears pneumocystis infection.
Topics: Animals; Cell Differentiation; Drug Synergism; Drug Therapy, Combination; Female; Humans; Immunocomp | 2013 |
[ATTEMPTED TREATMENT OF PNEUMOCYSTIS PNEUMONIA IN INFANTS. 4 CASES OF RECOVERY].
Topics: Antimony; Antiprotozoal Agents; Humans; Infant; Plasma Cells; Pneumonia; Pneumonia, Pneumocystis; Pr | 1963 |
When the book is wrong.
Topics: Adult; Anti-Infective Agents; Belgium; Contraindications; Databases, Factual; Drug Interactions; Fem | 2007 |
Methaemoglobinaemia causing progressive dyspnoea and cyanosis during treatment of Pneumocystis jirovecii pneumonia.
Topics: Adult; Anti-Bacterial Agents; Clindamycin; Cyanosis; Dyspnea; Humans; Male; Methemoglobinemia; Pneum | 2007 |
Drugs for AIDS and associated infections.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifunga | 1995 |
Dilemmas in the prophylaxis of Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Clindamycin; Dapso | 1994 |
Toxicity of clindamycin and primaquine treatment of AIDS-related Pneumocystis carinii pneumonia.
Topics: AIDS-Related Opportunistic Infections; Clindamycin; Drug Therapy, Combination; Humans; Pneumonia, Pn | 1993 |
[Clindamycin and primaquine in the treatment of pulmonary pneumocystosis in a HIV-positive female patient].
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Clindamycin; Drug | 1993 |
Dapsone- and primaquine-induced methemoglobinemia in HIV-infected individuals.
Topics: Adult; AIDS-Related Opportunistic Infections; Anemia, Hemolytic; Anti-Infective Agents; Clindamycin; | 1996 |
Clindamycin/primaquine as prophylaxis for Pneumocystis carinii pneumonia.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antimalarials; CD4 Lymphocyte Count; Clindamyci | 1996 |
[Primaquine].
Topics: Contraindications; Humans; Malaria; Pneumonia, Pneumocystis; Primaquine | 2001 |
Primaquine-induced methemoglobinemia during treatment of Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Humans; Male; Methemoglobinemia; Middle Aged; Pneumonia, Pneumoc | 1992 |
Role of clindamycin with or without another agent for treatment of pneumocystosis in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Clindamycin; Drug Therapy, Combination; Humans; Pneumonia, Pneum | 1992 |
Efficacy of intermittent dosage of 8-aminoquinolines for therapy or prophylaxis of Pneumocystis pneumonia in rats.
Topics: Aminoquinolines; Animals; Clindamycin; Disease Models, Animal; Drug Administration Schedule; Female; | 1992 |
Salvage therapy with clindamycin/primaquine for Pneumocystis carinii pneumonia.
Topics: Administration, Oral; Adolescent; Adult; Aged; Clindamycin; Drug Therapy, Combination; Female; Human | 1992 |
8-Aminoquinolines from Walter Reed Army Institute for Research for treatment and prophylaxis of Pneumocystis pneumonia in rat models.
Topics: Aminoquinolines; Animals; Clindamycin; Drug Therapy, Combination; Female; Lung; Male; Pneumonia, Pne | 1991 |
Clindamycin/primaquine therapy and secondary prophylaxis against Pneumocystis carinii pneumonia in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Clindamycin; Drug Administration Sc | 1990 |
Clindamycin/primaquine for Pneumocystis carinii pneumonia.
Topics: Adult; Clindamycin; Drug Therapy, Combination; HIV Seropositivity; Humans; Male; Methemoglobinemia; | 1989 |
Activity of clindamycin with primaquine against Pneumocystis carinii in vitro and in vivo.
Topics: Animals; Cells, Cultured; Clindamycin; Female; Pneumocystis; Pneumonia, Pneumocystis; Primaquine; Ra | 1988 |