Page last updated: 2024-11-03

primaquine and Multiple Sclerosis

primaquine has been researched along with Multiple Sclerosis in 2 studies

Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.

Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Thome, R1
Casella, G1
Lotfi, N1
Ishikawa, LWL1
Wang, Q1
Ciric, B1
Zhang, GX1
Rostami, A1
SULLI, G1
VARRONE, F1

Reviews

1 review available for primaquine and Multiple Sclerosis

ArticleYear
[EXTRAMALARIAL THERAPUETIC APPLICATIONS OF ANTIMALARIAL DRUGS. 1. CLINICAL UTILIZATIONS].
    La Clinica terapeutica, 1963, Oct-31, Volume: 27

    Topics: Amodiaquine; Antimalarials; Chloroquine; Collagen Diseases; Dermatology; Drug Utilization; Epilepsy;

1963

Other Studies

1 other study available for primaquine and Multiple Sclerosis

ArticleYear
Primaquine elicits Foxp3
    Journal of autoimmunity, 2020, Volume: 114

    Topics: Animals; Antimalarials; Autoimmunity; Dendritic Cells; Disease Models, Animal; Encephalomyelitis, Au

2020