primaquine has been researched along with Leishmania Infection in 9 studies
Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tafenoquine was less active against intracellular Trypanosoma cruzi amastigotes, with an IC(50) of 21." | 1.36 | Antileishmanial and antitrypanosomal activities of the 8-aminoquinoline tafenoquine. ( Croft, SL; Gamarro, F; Yardley, V, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reynolds, KA | 1 |
| Loughlin, WA | 1 |
| Young, DJ | 1 |
| Yardley, V | 1 |
| Gamarro, F | 1 |
| Croft, SL | 1 |
| NEAL, RA | 2 |
| Steck, EA | 1 |
| von Sonnenburg, F | 1 |
| Prüfer, L | 1 |
| Beveridge, E | 1 |
| Caldwell, IC | 1 |
| Latter, VS | 1 |
| Udall, V | 1 |
| Waldron, MM | 1 |
| Banerjee, G | 1 |
| Medda, S | 1 |
| Basu, MK | 1 |
| Scovill, JP | 1 |
| Klayman, DL | 1 |
| Woods, TS | 1 |
| Sweeney, TR | 1 |
| Bryceson, AD | 1 |
3 reviews available for primaquine and Leishmania Infection
| Article | Year |
|---|---|
Quinolines as chemotherapeutic agents for leishmaniasis.
Topics: Aminoquinolines; Animals; Antiprotozoal Agents; Clinical Trials as Topic; Drug Evaluation, Preclinic | 2013 |
The chemotherapy of protozoal infections: whither?
Topics: Animals; Antimony; Antimony Sodium Gluconate; Antiprotozoal Agents; Disease Models, Animal; Glycolip | 1981 |
[Progress in immunodiagnosis and chemotherapy of protozoan infections].
Topics: Amebiasis; Animals; Antibodies; Babesiosis; Chloroquine; Drug Resistance, Microbial; Giardiasis; Hum | 1983 |
6 other studies available for primaquine and Leishmania Infection
| Article | Year |
|---|---|
Antileishmanial and antitrypanosomal activities of the 8-aminoquinoline tafenoquine.
Topics: Aminoquinolines; Animals; Antiprotozoal Agents; Female; Inhibitory Concentration 50; Leishmania dono | 2010 |
CHEMOTHERAPY OF CUTANEOUS LEISHMANIASIS: LEISHMANIA TROPICA INFECTIONS IN MICE.
Topics: Amidines; Animals; Antimony; Antiprotozoal Agents; Chloroquine; Chlortetracycline; Dapsone; Deoxyrib | 1964 |
The activity against Trypanosoma cruzi and cutaneous leishmaniasis, and toxicity, of moxipraquine (349C59).
Topics: Aminoquinolines; Animals; Chagas Disease; Culture Techniques; Female; Fetus; Furazolidone; Guinea Pi | 1980 |
A novel peptide-grafted liposomal delivery system targeted to macrophages.
Topics: Animals; Antimalarials; Chemotaxis; Cricetinae; Drug Carriers; Leishmaniasis; Liposomes; Macrophages | 1998 |
Primaquine analogues: derivatives of 4-amino-2-methoxyacridine.
Topics: Animals; Cricetinae; Haplorhini; Leishmaniasis; Macaca mulatta; Mesocricetus; Mice; Primaquine; Schi | 1979 |
Diffuse cutaneous leishmaniasis in Ethiopia. II. Treatment.
Topics: Adolescent; Amidines; Amphotericin B; Antimony; Antiprotozoal Agents; Child; Chloroquine; Female; Gl | 1970 |