primaquine has been researched along with Genetic Predisposition in 3 studies
Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dosage regimen of primaquine for treatment of both Plasmodium falciparum and Plasmodium vivax malaria may need to be optimized, based on endemic areas with supporting data on G6PD variants." | 1.37 | Prevalence and distribution of glucose-6-phosphate dehydrogenase (G6PD) variants in Thai and Burmese populations in malaria endemic areas of Thailand. ( Chaijaroenkul, W; Hongkaew, Y; Kuesap, J; Na-Bangchang, K; Phompradit, P; Rueangweerayut, R; Yamnuan, R, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Satyagraha, AW | 1 |
| Sadhewa, A | 1 |
| Panggalo, LV | 1 |
| Subekti, D | 1 |
| Elyazar, I | 1 |
| Soebianto, S | 1 |
| Mahpud, N | 1 |
| Harahap, AR | 1 |
| Baird, JK | 1 |
| Awandu, SS | 1 |
| Raman, J | 1 |
| Makhanthisa, TI | 1 |
| Kruger, P | 1 |
| Frean, J | 1 |
| Bousema, T | 1 |
| Niemand, J | 1 |
| Birkholtz, LM | 1 |
| Phompradit, P | 1 |
| Kuesap, J | 1 |
| Chaijaroenkul, W | 1 |
| Rueangweerayut, R | 1 |
| Hongkaew, Y | 1 |
| Yamnuan, R | 1 |
| Na-Bangchang, K | 1 |
3 other studies available for primaquine and Genetic Predisposition
| Article | Year |
|---|---|
Genotypes and phenotypes of G6PD deficiency among Indonesian females across diagnostic thresholds of G6PD activity guiding safe primaquine therapy of latent malaria.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Child; Female; Gene Expression Regulation | 2021 |
Understanding human genetic factors influencing primaquine safety and efficacy to guide primaquine roll-out in a pre-elimination setting in southern Africa.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Female; Gene Expression Regulat | 2018 |
Prevalence and distribution of glucose-6-phosphate dehydrogenase (G6PD) variants in Thai and Burmese populations in malaria endemic areas of Thailand.
Topics: Adolescent; Adult; Case-Control Studies; Endemic Diseases; Ethnicity; Female; Gene Frequency; Geneti | 2011 |