primaquine has been researched along with Enlarged Spleen in 6 studies
Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We evaluated the efficacy, safety, and tolerability of alternative primaquine dosing regimens combined with artesunate among 399 Thai patients with acute, symptomatic P." | 6.73 | High-dose primaquine regimens against relapse of Plasmodium vivax malaria. ( Baird, JK; Brittenham, GM; Krudsood, S; Looareesuwan, S; Phophak, N; Tangpukdee, N; Wilairatana, P, 2008) |
| " We evaluated the efficacy, safety, and tolerability of alternative primaquine dosing regimens combined with artesunate among 399 Thai patients with acute, symptomatic P." | 2.73 | High-dose primaquine regimens against relapse of Plasmodium vivax malaria. ( Baird, JK; Brittenham, GM; Krudsood, S; Looareesuwan, S; Phophak, N; Tangpukdee, N; Wilairatana, P, 2008) |
| "Malaria is an increasing hazard of tropical travel." | 1.26 | Imported malaria in adults in Auckland. ( Ellis-Pegler, RB; Palmer, CW, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krudsood, S | 1 |
| Tangpukdee, N | 1 |
| Wilairatana, P | 1 |
| Phophak, N | 1 |
| Baird, JK | 1 |
| Brittenham, GM | 1 |
| Looareesuwan, S | 1 |
| Hamilton, PJ | 2 |
| Richmond, J | 1 |
| Donaldson, GW | 1 |
| Williams, R | 1 |
| Hutt, MS | 2 |
| Lugumba, V | 1 |
| Palmer, CW | 1 |
| Ellis-Pegler, RB | 1 |
| Seeler, RA | 1 |
| Miller, RA | 1 |
| Lin, CH | 1 |
| Lin, SK | 1 |
| Schneider, MD | 1 |
| Gebbie, DA | 1 |
| Lothe, F | 1 |
| Wilks, NE | 1 |
1 trial available for primaquine and Enlarged Spleen
| Article | Year |
|---|---|
High-dose primaquine regimens against relapse of Plasmodium vivax malaria.
Topics: Adolescent; Adult; Antimalarials; Dose-Response Relationship, Drug; Drug Administration Schedule; Fe | 2008 |
5 other studies available for primaquine and Enlarged Spleen
| Article | Year |
|---|---|
Splenectomy in "big spleen disease".
Topics: Adult; Blood Cell Count; Follow-Up Studies; Hemoglobins; Humans; Malaria; Male; Middle Aged; Primaqu | 1967 |
Imported malaria in adults in Auckland.
Topics: Adolescent; Adult; Chloroquine; Drug Resistance, Microbial; Female; Humans; Kenya; Malaria; Male; Mi | 1982 |
Transfusion-induced malaria. Plasmodium vivax in a 5-month-old child.
Topics: Chloroquine; Fever; Hemolysis; Hepatomegaly; Humans; Infant; Malaria; Male; Plasmodium vivax; Primaq | 1973 |
Characteristics and cross-resistance patterns of chloroquine-resistant Plasmodium berghei infections in mice.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Female; Hemat | 1968 |
Anaemia in pregnancy associated with "big spleen disease".
Topics: Adolescent; Adult; Anemia, Hypochromic; Chloroquine; Female; Humans; Liver; Malaria; Pregnancy; Preg | 1966 |