Page last updated: 2024-11-03

primaquine and Drug Overdose

primaquine has been researched along with Drug Overdose in 5 studies

Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"We attempted to clarify this issue by comparing the clinical course of methemoglobinemia caused by dapsone and that caused by other toxic agents."7.83Difference of the clinical course and outcome between dapsone-induced methemoglobinemia and other toxic-agent-induced methemoglobinemia. ( Ahn, S; Kim, WY; Kim, YJ; Lee, JH; Lee, YS; Lim, KS; Oh, BJ; Ryoo, SM; Seo, DW; Sohn, CH, 2016)
" Primaquine in particular is known to cause methemoglobinemia and hemolytic anemia."4.02Primaquine overdose in a toddler. ( Pomeranz, E; Ponce, DM; Schaeffer, W; Visclosky, T, 2021)
"We attempted to clarify this issue by comparing the clinical course of methemoglobinemia caused by dapsone and that caused by other toxic agents."3.83Difference of the clinical course and outcome between dapsone-induced methemoglobinemia and other toxic-agent-induced methemoglobinemia. ( Ahn, S; Kim, WY; Kim, YJ; Lee, JH; Lee, YS; Lim, KS; Oh, BJ; Ryoo, SM; Seo, DW; Sohn, CH, 2016)
"The patient was given chloroquine by his captain in a dosage regimen appropriate for quinine (2 tablets 3 times daily for 7 d)."1.32Toxicity related to chloroquine treatment of resistant vivax malaria. ( Barrett, PH; Davis, TM; Ilett, KF; Syed, DA, 2003)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Visclosky, T1
Schaeffer, W1
Pomeranz, E1
Ponce, DM1
Kim, YJ1
Sohn, CH1
Ryoo, SM1
Ahn, S1
Seo, DW1
Lee, YS1
Lee, JH1
Oh, BJ1
Lim, KS1
Kim, WY1
Davis, TM1
Syed, DA1
Ilett, KF1
Barrett, PH1
Sin, DD1
Shafran, SD1
Lobel, HO1
Coyne, PE1
Rosenthal, PJ1

Other Studies

5 other studies available for primaquine and Drug Overdose

ArticleYear
Primaquine overdose in a toddler.
    The American journal of emergency medicine, 2021, Volume: 45

    Topics: Anemia, Hemolytic; Antimalarials; Child, Preschool; Drug Overdose; Glucosephosphate Dehydrogenase De

2021
Difference of the clinical course and outcome between dapsone-induced methemoglobinemia and other toxic-agent-induced methemoglobinemia.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Dapsone; Dose-Response Relationship, Drug; Dru

2016
Toxicity related to chloroquine treatment of resistant vivax malaria.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:4

    Topics: Adult; Animals; Antimalarials; Atovaquone; Chloroquine; Drug Overdose; Humans; Malaria, Vivax; Male;

2003
Dapsone- and primaquine-induced methemoglobinemia in HIV-infected individuals.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Aug-15, Volume: 12, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Anemia, Hemolytic; Anti-Infective Agents; Clindamycin;

1996
Drug overdoses with antimalarial agents: prescribing and dispensing errors.
    JAMA, 1998, Nov-04, Volume: 280, Issue:17

    Topics: Aged; Aged, 80 and over; Antifungal Agents; Antimalarials; Drug Overdose; Female; Humans; Malaria, V

1998