primaquine has been researched along with Cyanosis in 5 studies
Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.
Cyanosis: A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The most common adverse events were nausea, abdominal pain, headache and insomnia, many of which were mild in severity (30%; 60/203) and transient; 19% of subjects (39/203) experienced moderate (with some interference with daily duties requiring no or minimal medical therapy) adverse events." | 2.76 | Evaluation of the safety and tolerability of a short higher-dose primaquine regimen for presumptive anti-relapse therapy in healthy subjects. ( Baker, J; Ebringer, A; Edstein, MD; Heathcote, G; Shanks, GD; Waller, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ebringer, A | 1 |
| Heathcote, G | 1 |
| Baker, J | 1 |
| Waller, M | 1 |
| Shanks, GD | 1 |
| Edstein, MD | 1 |
| HANSEN, JE | 1 |
| CLEVE, EA | 1 |
| PRUITT, FW | 1 |
| Hamill, M | 1 |
| Harte, D | 1 |
| Miller, RF | 1 |
| Cohen, RJ | 1 |
| Sachs, JR | 1 |
| Wicker, DJ | 1 |
| Conrad, ME | 1 |
| Sietsma, A | 1 |
| Naughton, MA | 1 |
| Harley, JD | 1 |
1 trial available for primaquine and Cyanosis
| Article | Year |
|---|---|
Evaluation of the safety and tolerability of a short higher-dose primaquine regimen for presumptive anti-relapse therapy in healthy subjects.
Topics: Abdominal Pain; Adult; Antimalarials; Cyanosis; Drug Administration Schedule; Female; Headache; Huma | 2011 |
4 other studies available for primaquine and Cyanosis
| Article | Year |
|---|---|
Relapse of vivax malaria treated with primaquine and report of one case of cyanosis (methemoglobinemia) due to primaquine.
Topics: Antimalarials; Chronic Disease; Cyanosis; Humans; Malaria; Malaria, Vivax; Methemoglobinemia; Primaq | 1954 |
Methaemoglobinaemia causing progressive dyspnoea and cyanosis during treatment of Pneumocystis jirovecii pneumonia.
Topics: Adult; Anti-Bacterial Agents; Clindamycin; Cyanosis; Dyspnea; Humans; Male; Methemoglobinemia; Pneum | 2007 |
Methemoglobinemia provoked by malarial chemoprophylaxis in Vietnam.
Topics: Antimalarials; Chloroquine; Cyanosis; Dapsone; Diseases in Twins; Erythrocytes; Female; Hematocrit; | 1968 |
"Blue soldiers".
Topics: Australia; Chloroquine; Cyanosis; Humans; Male; Methemoglobinemia; Military Medicine; Primaquine | 1968 |