Page last updated: 2024-11-03

primaquine and Cyanosis

primaquine has been researched along with Cyanosis in 5 studies

Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.

Cyanosis: A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule.

Research Excerpts

ExcerptRelevanceReference
" The most common adverse events were nausea, abdominal pain, headache and insomnia, many of which were mild in severity (30%; 60/203) and transient; 19% of subjects (39/203) experienced moderate (with some interference with daily duties requiring no or minimal medical therapy) adverse events."2.76Evaluation of the safety and tolerability of a short higher-dose primaquine regimen for presumptive anti-relapse therapy in healthy subjects. ( Baker, J; Ebringer, A; Edstein, MD; Heathcote, G; Shanks, GD; Waller, M, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ebringer, A1
Heathcote, G1
Baker, J1
Waller, M1
Shanks, GD1
Edstein, MD1
HANSEN, JE1
CLEVE, EA1
PRUITT, FW1
Hamill, M1
Harte, D1
Miller, RF1
Cohen, RJ1
Sachs, JR1
Wicker, DJ1
Conrad, ME1
Sietsma, A1
Naughton, MA1
Harley, JD1

Trials

1 trial available for primaquine and Cyanosis

ArticleYear
Evaluation of the safety and tolerability of a short higher-dose primaquine regimen for presumptive anti-relapse therapy in healthy subjects.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2011, Volume: 105, Issue:10

    Topics: Abdominal Pain; Adult; Antimalarials; Cyanosis; Drug Administration Schedule; Female; Headache; Huma

2011

Other Studies

4 other studies available for primaquine and Cyanosis

ArticleYear
Relapse of vivax malaria treated with primaquine and report of one case of cyanosis (methemoglobinemia) due to primaquine.
    The American journal of the medical sciences, 1954, Volume: 227, Issue:1

    Topics: Antimalarials; Chronic Disease; Cyanosis; Humans; Malaria; Malaria, Vivax; Methemoglobinemia; Primaq

1954
Methaemoglobinaemia causing progressive dyspnoea and cyanosis during treatment of Pneumocystis jirovecii pneumonia.
    International journal of STD & AIDS, 2007, Volume: 18, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Clindamycin; Cyanosis; Dyspnea; Humans; Male; Methemoglobinemia; Pneum

2007
Methemoglobinemia provoked by malarial chemoprophylaxis in Vietnam.
    The New England journal of medicine, 1968, Nov-21, Volume: 279, Issue:21

    Topics: Antimalarials; Chloroquine; Cyanosis; Dapsone; Diseases in Twins; Erythrocytes; Female; Hematocrit;

1968
"Blue soldiers".
    The Medical journal of Australia, 1968, Nov-02, Volume: 2, Issue:18

    Topics: Australia; Chloroquine; Cyanosis; Humans; Male; Methemoglobinemia; Military Medicine; Primaquine

1968