Page last updated: 2024-11-03

primaquine and Chronic Illness

primaquine has been researched along with Chronic Illness in 13 studies

Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.

Research Excerpts

ExcerptRelevanceReference
"Primaquine was effective in preventing P."5.72Relapse of Plasmodium vivax and Plasmodium ovale Malaria With and Without Primaquine Treatment in a Nonendemic Area. ( Björklund, D; Carlander, C; Färnert, A; Hellgren, U; Hervius Askling, H; Sondén, K; Stenström, C; Wångdahl, A; Wyss, K; Zhang, J, 2022)
"This suggested that 32 of the 47 recurrences were probable relapses of which 22 (69%) were genetically homologous."2.77Genotyping of Plasmodium vivax reveals both short and long latency relapse patterns in Kolkata. ( Addy, M; Day, NP; Dondorp, AM; Imwong, M; Kim, JR; Maji, AK; Nandy, A; Pukrittayakamee, S; White, NJ, 2012)
"Primaquine was effective in preventing P."1.72Relapse of Plasmodium vivax and Plasmodium ovale Malaria With and Without Primaquine Treatment in a Nonendemic Area. ( Björklund, D; Carlander, C; Färnert, A; Hellgren, U; Hervius Askling, H; Sondén, K; Stenström, C; Wångdahl, A; Wyss, K; Zhang, J, 2022)
"vivax malaria were randomized to receive chloroquine (CQ; 25 mg base/kg given over 3 days) alone or together with primaquine (PQ; 0."1.51Efficacy of Primaquine in Preventing Short- and Long-Latency Plasmodium vivax Relapses in Nepal. ( Adhikari, B; Banjara, MR; Chotivanich, K; Das Thakur, G; Day, NPJ; Ghimire, P; Hanboonkunupakarn, B; Imwong, M; Pukrittayakamee, S; Rijal, KR; White, NJ, 2019)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (30.77)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Gandrala, D2
Gupta, N2
Lavu, A2
Nallapati, VT2
Guddattu, V2
Saravu, K2
Chamma-Siqueira, NN1
Viana, GMR1
Macedo de Oliveira, A1
Wångdahl, A1
Sondén, K1
Wyss, K1
Stenström, C1
Björklund, D1
Zhang, J1
Hervius Askling, H1
Carlander, C1
Hellgren, U1
Färnert, A1
Sümer, Ş1
Aktuğ Demir, N1
Ural, O1
Çimen, G1
Yalçınkaya, E1
Rijal, KR1
Adhikari, B1
Ghimire, P1
Banjara, MR1
Das Thakur, G1
Hanboonkunupakarn, B1
Imwong, M2
Chotivanich, K1
Day, NPJ1
White, NJ2
Pukrittayakamee, S2
Rosenthal, PJ1
Kim, JR1
Nandy, A1
Maji, AK1
Addy, M1
Dondorp, AM1
Day, NP1
HANSEN, JE1
CLEVE, EA1
PRUITT, FW1
ARNOLD, J1
ALVING, AS1
HOCKWALD, RS1
CLAYMAN, CB1
DERN, RJ1
BEUTLER, E1
JEFFERY, GM1
Trier, JS1
Moxey, PC1
Schimmel, EM1
Robles, E1
Fisher, GU1
Gordon, MP1
Lobel, HO1
Runcik, K1
Wilks, NE1
Turner, PP1
Somers, K1
Markandya, OP1
Wiseman, RA1

Trials

1 trial available for primaquine and Chronic Illness

ArticleYear
Genotyping of Plasmodium vivax reveals both short and long latency relapse patterns in Kolkata.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Adolescent; Adult; Antimalarials; Chloroquine; Chronic Disease; Female; Genotype; Genotyping Techniq

2012

Other Studies

12 other studies available for primaquine and Chronic Illness

ArticleYear
Recurrence in
    F1000Research, 2022, Volume: 11

    Topics: Adult; Antimalarials; Chronic Disease; Follow-Up Studies; Humans; India; Malaria, Vivax; Plasmodium

2022
Higher-Dose Primaquine to Prevent Relapse of Plasmodium vivax Malaria. Reply.
    The New England journal of medicine, 2022, 07-21, Volume: 387, Issue:3

    Topics: Antimalarials; Chronic Disease; Humans; Malaria, Vivax; Plasmodium vivax; Primaquine; Recurrence

2022
Relapse of Plasmodium vivax and Plasmodium ovale Malaria With and Without Primaquine Treatment in a Nonendemic Area.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 04-09, Volume: 74, Issue:7

    Topics: Antimalarials; Chronic Disease; Humans; Malaria; Malaria, Vivax; Plasmodium ovale; Plasmodium vivax;

2022
A Malaria Case Followed By Relapse.
    Turkiye parazitolojii dergisi, 2018, Volume: 42, Issue:2

    Topics: Animals; Anopheles; Antimalarials; Chronic Disease; Diagnosis, Differential; Humans; Malaria, Vivax;

2018
Efficacy of Primaquine in Preventing Short- and Long-Latency Plasmodium vivax Relapses in Nepal.
    The Journal of infectious diseases, 2019, 07-02, Volume: 220, Issue:3

    Topics: Adolescent; Adult; Antimalarials; Chloroquine; Chronic Disease; Drug Therapy, Combination; Female; F

2019
A shorter course for anti-relapse therapy against vivax malaria.
    Lancet (London, England), 2019, 09-14, Volume: 394, Issue:10202

    Topics: Antimalarials; Chronic Disease; Humans; Malaria, Vivax; Primaquine; Recurrence

2019
Relapse of vivax malaria treated with primaquine and report of one case of cyanosis (methemoglobinemia) due to primaquine.
    The American journal of the medical sciences, 1954, Volume: 227, Issue:1

    Topics: Antimalarials; Chronic Disease; Cyanosis; Humans; Malaria; Malaria, Vivax; Methemoglobinemia; Primaq

1954
The effect of continuous and intermittent primaquine therapy on the relapse rate of Chesson strain vivax malaria.
    The Journal of laboratory and clinical medicine, 1954, Volume: 44, Issue:3

    Topics: Antimalarials; Chronic Disease; Humans; Malaria; Malaria, Vivax; Primaquine; Recurrence

1954
Chronic intestinal coccidiosis in man: intestinal morphology and response to treatment.
    Gastroenterology, 1974, Volume: 66, Issue:5

    Topics: Antiprotozoal Agents; Biopsy; Chloroquine; Chronic Disease; Coccidiosis; Diagnosis, Differential; Di

1974
Malaria in soldiers returning from Vietnam. Epidemiologic, therapeutic, and clinical studies.
    The American journal of tropical medicine and hygiene, 1970, Volume: 19, Issue:1

    Topics: Adult; Black or African American; Black People; Chloroquine; Chronic Disease; Hospitalization; Human

1970
Chronic ill-health from unrecognized malaria.
    East African medical journal, 1965, Volume: 42, Issue:11

    Topics: Adult; Africa, Eastern; Arrhythmias, Cardiac; Chronic Disease; Female; Fluorescent Antibody Techniqu

1965
Relapse after standard treatment of malaria.
    British medical journal, 1970, May-09, Volume: 2, Issue:5705

    Topics: Adult; Chloroquine; Chronic Disease; Humans; Malaria; Male; Primaquine

1970