primaquine has been researched along with Body Weight in 11 studies
Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Relapse of Plasmodium vivax malaria following standard primaquine dosing has been reported from many areas, and more recently from sub-Saharan Africa." | 7.70 | Short report: a consideration of primaquine dose adjustment for radical cure of Plasmodium vivax malaria. ( Kurnik, D; Regev-Yochay, G; Schwartz, E, 2000) |
| "Relapse of Plasmodium vivax malaria following standard primaquine dosing has been reported from many areas, and more recently from sub-Saharan Africa." | 3.70 | Short report: a consideration of primaquine dose adjustment for radical cure of Plasmodium vivax malaria. ( Kurnik, D; Regev-Yochay, G; Schwartz, E, 2000) |
| "Primaquine doses were calculated using allometric scaling to derive a weight-based primaquine regimen over a weight range from 5 to 100 kg." | 1.62 | Development of weight and age-based dosing of daily primaquine for radical cure of vivax malaria. ( Buchy, P; Debackere, M; Dondorp, AM; Dysoley, L; Fairhurst, RM; H Nosten, F; Hien, TT; Hoglund, RM; Kheang, ST; Kheng, S; Landier, J; Mayxay, M; Menard, D; Mukaka, M; Muth, S; Neeraj, K; Nguyen, TN; Peerawaranun, P; Peto, TJ; Phommasone, K; Rithea, L; Roca-Feltrer, A; Say, C; Smithuis, F; Song, N; Tarantola, A; Tarning, J; Taylor, WR; Tripura, R; von Seidlein, L; White, NJ, 2021) |
| "Two Plasmodium vivax recurrences in a Peruvian sailor with weight above the 60 kg (cap for primaquine dosage) highlight the importance of adequate radical cure weight dosage for patient treatment and control efforts, particularly within the military." | 1.42 | Repeated Plasmodium vivax malaria relapses in a Peruvian sailor. ( Cavalcanti, S; Gonzalez, S; Lescano, AG; McFarland, AP; Mercado, A; Sanchez, JF; Ventocilla, JA, 2015) |
| "Primaquine treatment did not affect diabetic rats." | 1.29 | Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats. ( Archibald, V; Cameron, NE; Cotter, MA; Dines, KC; Maxfield, EK, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Taylor, WR | 1 |
| Hoglund, RM | 1 |
| Peerawaranun, P | 1 |
| Nguyen, TN | 1 |
| Hien, TT | 1 |
| Tarantola, A | 1 |
| von Seidlein, L | 1 |
| Tripura, R | 1 |
| Peto, TJ | 1 |
| Dondorp, AM | 1 |
| Landier, J | 1 |
| H Nosten, F | 1 |
| Smithuis, F | 1 |
| Phommasone, K | 1 |
| Mayxay, M | 1 |
| Kheang, ST | 1 |
| Say, C | 1 |
| Neeraj, K | 1 |
| Rithea, L | 1 |
| Dysoley, L | 1 |
| Kheng, S | 1 |
| Muth, S | 1 |
| Roca-Feltrer, A | 1 |
| Debackere, M | 1 |
| Fairhurst, RM | 1 |
| Song, N | 1 |
| Buchy, P | 1 |
| Menard, D | 1 |
| White, NJ | 1 |
| Tarning, J | 1 |
| Mukaka, M | 1 |
| Sohsuebngarm, D | 1 |
| Sasipreeyajan, J | 1 |
| Nithiuthai, S | 1 |
| Chansiripornchai, N | 1 |
| McFarland, AP | 1 |
| Sanchez, JF | 1 |
| Mercado, A | 1 |
| Ventocilla, JA | 1 |
| Cavalcanti, S | 1 |
| Gonzalez, S | 1 |
| Lescano, AG | 1 |
| Karell, P | 1 |
| Ahola, K | 1 |
| Karstinen, T | 1 |
| Kolunen, H | 1 |
| Siitari, H | 1 |
| Brommer, JE | 1 |
| Elmes, NJ | 1 |
| Bennett, SM | 1 |
| Abdalla, H | 1 |
| Carthew, TL | 1 |
| Edstein, MD | 1 |
| Goller, JL | 1 |
| Jolley, D | 1 |
| Ringwald, P | 1 |
| Biggs, BA | 1 |
| Cameron, NE | 1 |
| Cotter, MA | 1 |
| Archibald, V | 1 |
| Dines, KC | 1 |
| Maxfield, EK | 1 |
| Schwartz, E | 1 |
| Regev-Yochay, G | 1 |
| Kurnik, D | 1 |
| Oltersdorf, U | 2 |
| Bitsch, I | 2 |
| Klapp-Kunsemüller, E | 2 |
| Puri, SK | 1 |
| Srivastava, R | 1 |
| Pandey, VC | 1 |
| Sethi, N | 1 |
| Dutta, GP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment of Efficacy and Safety of Thioctic Acid in the Oral Treatment of Symptomatic Diabetic Neuropathy (SYDNEY 2) Randomised, Double-blind,Placebo-controlled Multicentre Trial With 4 Parallel Groups[NCT00328601] | Phase 3 | 170 participants | Interventional | 2005-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for primaquine and Body Weight
| Article | Year |
|---|---|
Regional differences in the response of Plasmodium vivax malaria to primaquine as anti-relapse therapy.
Topics: Animals; Antimalarials; Body Weight; Brazil; Humans; India; Malaria, Vivax; Plasmodium vivax; Primaq | 2007 |
1 trial available for primaquine and Body Weight
| Article | Year |
|---|---|
The efficacy of artesunate, chloroquine, doxycycline, primaquine and a combination of artesunate and primaquine against avian malaria in broilers.
Topics: Analysis of Variance; Animals; Antimalarials; Artemisinins; Artesunate; Body Weight; Chickens; Chlor | 2014 |
9 other studies available for primaquine and Body Weight
| Article | Year |
|---|---|
Development of weight and age-based dosing of daily primaquine for radical cure of vivax malaria.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antimalarials; Body Weight; Child; Child, P | 2021 |
Repeated Plasmodium vivax malaria relapses in a Peruvian sailor.
Topics: Adult; Antimalarials; Body Weight; Genotype; Genotyping Techniques; Humans; Malaria, Vivax; Male; Mi | 2015 |
Blood parasites mediate morph-specific maintenance costs in a colour polymorphic wild bird.
Topics: Animals; Antiparasitic Agents; Body Weight; Chloroquine; Color; Female; Haemosporida; Host-Parasite | 2011 |
Lack of sex effect on the pharmacokinetics of primaquine.
Topics: Adult; Animals; Antimalarials; Australia; Body Weight; Female; Humans; Malaria, Vivax; Male; Metabol | 2006 |
Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Inositol; Male; Motor Neurons; | 1994 |
Short report: a consideration of primaquine dose adjustment for radical cure of Plasmodium vivax malaria.
Topics: Antimalarials; Body Weight; Drug Resistance; Humans; Malaria, Vivax; Primaquine; Retrospective Studi | 2000 |
Interactions between malnutrition and primaquine studied on Wistar rats. II. Complex vitamin B deficiency and thiamine deficiency.
Topics: Animals; Body Weight; Erythrocytes; Glucosephosphate Dehydrogenase; Liver; Male; Methemoglobinemia; | 1976 |
Methemoglobin toxicity and hematological studies on malaria anti-relapse compound CDRI 80/53 in dogs.
Topics: Aminoquinolines; Animals; Antimalarials; Appetite; Body Weight; Dogs; Female; Male; Methemoglobinemi | 1989 |
Interactions between malnutrition and primaquine studied on wistar rats. I. Protein deficiency.
Topics: Animals; Blood Proteins; Body Weight; Caseins; Eating; Erythrocyte Count; Erythrocytes; Hematocrit; | 1974 |