primaquine has been researched along with Aging in 4 studies
Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Excerpt | Relevance | Reference |
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" There was no evidence of symptomatic hemolysis, and adverse events considered related to study drug (n = 4) were mild." | 1.48 | Safety of Single-Dose Primaquine in G6PD-Deficient and G6PD-Normal Males in Mali Without Malaria: An Open-Label, Phase 1, Dose-Adjustment Trial. ( Bousema, T; Brown, J; Chen, I; Diarra, K; Diawara, H; Dicko, A; Djimde, M; Gosling, R; Greenhouse, B; Hwang, J; Keita, M; Keita, S; Kone, D; Mahamar, A; Murphy, M; Niemi, M; Pett, H; Roh, ME; Sanogo, K, 2018) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chen, I | 1 |
Diawara, H | 1 |
Mahamar, A | 1 |
Sanogo, K | 1 |
Keita, S | 1 |
Kone, D | 1 |
Diarra, K | 1 |
Djimde, M | 1 |
Keita, M | 1 |
Brown, J | 1 |
Roh, ME | 1 |
Hwang, J | 1 |
Pett, H | 1 |
Murphy, M | 1 |
Niemi, M | 1 |
Greenhouse, B | 1 |
Bousema, T | 1 |
Gosling, R | 1 |
Dicko, A | 1 |
Betuela, I | 1 |
Bassat, Q | 1 |
Kiniboro, B | 1 |
Robinson, LJ | 1 |
Rosanas-Urgell, A | 1 |
Stanisic, D | 1 |
Siba, PM | 1 |
Alonso, PL | 1 |
Mueller, I | 1 |
BREWER, GJ | 1 |
POWELL, RD | 1 |
SWANSON, SH | 1 |
ALVING, AS | 1 |
Goldschmidt, L | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Determining a Tolerable Dose of Primaquine in G6PD-deficient Persons Without Malaria in Mali[NCT02535767] | Phase 1/Phase 2 | 28 participants (Actual) | Interventional | 2015-08-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
4 other studies available for primaquine and Aging
Article | Year |
---|---|
Safety of Single-Dose Primaquine in G6PD-Deficient and G6PD-Normal Males in Mali Without Malaria: An Open-Label, Phase 1, Dose-Adjustment Trial.
Topics: Adolescent; Adult; Aging; Antimalarials; Child; Child, Preschool; Dose-Response Relationship, Drug; | 2018 |
Tolerability and safety of primaquine in Papua New Guinean children 1 to 10 years of age.
Topics: Aging; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Cohort Studies | 2012 |
HEMOLYTIC EFFECT OF PRIMAQUINE. XVII. HEXOKINASE ACTIVITY OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE-DEFICIENT AND NORMAL ERYTHROCYTES.
Topics: Aging; Anemia, Hemolytic; Biomedical Research; Black People; Bloodletting; Erythrocyte Aging; Erythr | 1964 |
Variations in red cell glutathione with aging in male and female primaquine-sensitive Negroes.
Topics: Adult; Aged; Aging; Black People; Computers; Erythrocytes; Female; Glucosephosphate Dehydrogenase De | 1971 |