primaquine has been researched along with African Sleeping Sickness in 3 studies
Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eight other test compounds from the Cancer Chemotherapy National Service Center (CCNSC) were not toxic to cell growth, although two (4-biphenylcarboxylic acid and 1-[p-chlorobenzyl]-2-ethyl-5-methyl-indole-3-acetic acid) inhibited Crithidia alpha-glycerophosphate dehydrogenase below 1 mm." | 1.25 | Effects of some antitumor agents on growth and glycolytic enzymes of the flagellate Crithidia. ( Bacchi, CJ; Ciaccio, EI; Koren, LE, 1969) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shetty, RV | 1 |
| Blanton, CD | 1 |
| ROBERTSON, DH | 1 |
| Bacchi, CJ | 1 |
| Ciaccio, EI | 1 |
| Koren, LE | 1 |
3 other studies available for primaquine and African Sleeping Sickness
| Article | Year |
|---|---|
Synthesis of 2-substituted primaquine analogues as potential antimalarials.
Topics: Animals; Antimalarials; Cricetinae; Haplorhini; Leishmaniasis, Visceral; Macaca mulatta; Malaria; Mi | 1978 |
The haemolytic effect of primaquine and nitrofurazone in cases of sleeping sickness with the haemolytic trait.
Topics: Animals; Antimalarials; Black People; Cell Death; Hemolysis; Humans; Nitrofurans; Nitrofurazone; Pri | 1961 |
Effects of some antitumor agents on growth and glycolytic enzymes of the flagellate Crithidia.
Topics: Acetates; Acids; Antineoplastic Agents; Antiprotozoal Agents; Arsenicals; Benzoxazoles; Eukaryota; G | 1969 |