primaquine has been researched along with Acute Disease in 9 studies
Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the efficacy, safety and tolerability of an alternative short-course, artemisinin-based combination therapy for acute uncomplicated Plasmodium falciparum malaria, we compared Artequick--a fixed-dosed combination of artemisinin (80 mg), piperaquine (400 mg), and primaquine (4 mg), per tablet--with a standard regimen of artesunate-mefloquine." | 5.13 | Efficacy of Artequick versus artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand. ( Brittenham, GM; Kano, S; Krudsood, S; Li, G; Looareesuwan, S; Pengruksa, C; Phophak, N; Tangpukdee, N; Thanachartwet, V; Wilairatana, P, 2008) |
| "2." | 1.29 | Interactions among primaquine, malaria infection and other antimalarials in Thai subjects. ( Davis, TM; Edwards, G; McGrath, CS; Pukrittayakamee, S; Supanaranond, W; Ward, SA; White, NJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, P | 1 |
| Gao, X | 1 |
| Ishida, H | 1 |
| Amnuaysirikul, J | 1 |
| Weina, PJ | 1 |
| Grogl, M | 1 |
| O'Neil, MT | 1 |
| Li, Q | 1 |
| Caridha, D | 1 |
| Ohrt, C | 1 |
| Hickman, M | 1 |
| Magill, AJ | 1 |
| Ray, P | 1 |
| Laothamatas, J | 1 |
| Sammet, CL | 1 |
| Golay, X | 1 |
| Van Cauteren, M | 1 |
| Lekprasert, V | 1 |
| Tangpukdee, N | 2 |
| Krudsood, S | 2 |
| Leowattana, W | 1 |
| Wilairatana, P | 2 |
| Swaminathan, SV | 1 |
| DeLaPaz, RL | 1 |
| Brown, TR | 1 |
| Looareesuwan, S | 2 |
| Brittenham, GM | 2 |
| Thanachartwet, V | 1 |
| Pengruksa, C | 1 |
| Phophak, N | 1 |
| Kano, S | 1 |
| Li, G | 1 |
| Gogtay, NJ | 1 |
| Kamtekar, KD | 1 |
| Dalvi, SS | 1 |
| Chogle, AR | 1 |
| Aigal, U | 1 |
| Kshirsagar, NA | 1 |
| Carmona-Fonseca, J | 1 |
| Alvarez, G | 1 |
| Lazar, AI | 1 |
| Rønn, A | 1 |
| Bygbjerg, I | 1 |
| Edwards, G | 1 |
| McGrath, CS | 1 |
| Ward, SA | 1 |
| Supanaranond, W | 1 |
| Pukrittayakamee, S | 1 |
| Davis, TM | 1 |
| White, NJ | 1 |
| Reeve, PA | 1 |
| Toaliu, H | 1 |
| Kaneko, A | 1 |
| Hall, JJ | 1 |
| Ganczakowski, M | 1 |
3 trials available for primaquine and Acute Disease
| Article | Year |
|---|---|
Efficacy of Artequick versus artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Female | 2008 |
Preliminary report of the evaluation of the gametocytocidal action of bulaquine, in adult patients with acute, Plasmodium falciparum malaria.
Topics: Acute Disease; Adult; Animals; Antimalarials; Drug Therapy, Combination; Humans; Malaria, Falciparum | 2004 |
[Plasmodium vivax malaria: treatment of primary attacks with primaquine, in three different doses, and a fixed dose of chloroquine, Antioquia, Colombia, 2003-2004].
Topics: Acute Disease; Adult; Antimalarials; Chloroquine; Colombia; Female; Humans; Malaria, Vivax; Male; Pr | 2006 |
6 other studies available for primaquine and Acute Disease
| Article | Year |
|---|---|
An in vivo drug screening model using glucose-6-phosphate dehydrogenase deficient mice to predict the hemolytic toxicity of 8-aminoquinolines.
Topics: Acute Disease; Aminoquinolines; Anemia, Hemolytic; Animals; Antimalarials; Chloroquine; Disease Mode | 2013 |
Transient lesion in the splenium of the corpus callosum in acute uncomplicated falciparum malaria.
Topics: Acute Disease; Adult; Antimalarials; Artemisinins; Chloroquine; Corpus Callosum; Drug Therapy, Combi | 2014 |
Halofantrine in acute malaria.
Topics: Acute Disease; Antimalarials; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Malaria, Vivax | 1994 |
Unexpected high primaquine concentrations in acutely ill malaria patients.
Topics: Acute Disease; Humans; Malaria; Malaria, Vivax; Primaquine; Time Factors | 1993 |
Interactions among primaquine, malaria infection and other antimalarials in Thai subjects.
Topics: Acute Disease; Administration, Oral; Adult; Drug Interactions; Humans; Malaria, Falciparum; Male; Me | 1993 |
Acute intravascular haemolysis in Vanuatu following a single dose of primaquine in individuals with glucose-6-phosphate dehydrogenase deficiency.
Topics: Acute Disease; Adolescent; Adult; Anemia, Hemolytic; Glucosephosphate Dehydrogenase Deficiency; Hemo | 1992 |