Page last updated: 2024-11-03

prilocaine and Muscle Contraction

prilocaine has been researched along with Muscle Contraction in 19 studies

Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" Intraoperatively, severe spasm only occurred in the prilocaine 1 %-group."5.11[Obturator nerve block for transurethral surgery. comparing ropivacaine 0.75 % vs. prilocaine 1 %]. ( Braun, R; Büche, I; Kerger, H; Ruland, T; Waschke, KF, 2005)
"In searching for the 'ideal' muscle relaxant for use with intravenous regional anaesthesia, muscle relaxation was assessed with and without the addition of Atracurium to Bier's Block in four volunteers."3.67The use of muscle relaxant to supplement local anaesthetics for Bier's blocks. ( Harris, P; Heyes, F; McGlone, R, 1988)
" The efficacy of the sciatic block proved to be extremely high (> 95%), its success depending on the dosage of the local anaesthetic and correct execution of the peripheral nerve stimulation."2.67Prilocaine in lumbosacral plexus block--general efficacy and comparison of nerve stimulation amplitude. ( Bodenmueller, M; Kaiser, H; Klimpel, L; Niesel, HC, 1992)
" 3 The log dose-response curve for the contractile response of longitudinal muscle strips from guinea-pig intestine to carbachol was shifted in a parallel fashion by low concentrations of tetracaine, but flattened by higher doses."1.26The interaction of amine local anaesthetics with muscarinic receptors. ( Taylor, WJ; Wolf, A; Young, JM, 1980)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199012 (63.16)18.7374
1990's2 (10.53)18.2507
2000's3 (15.79)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bragagni, M1
Maestrelli, F1
Mennini, N1
Ghelardini, C1
Mura, P1
Petoe, MA1
Jaque, FA1
Byblow, WD1
Stinear, CM1
Joyce, PI1
Rizzi, D1
Caló, G1
Rowbotham, DJ1
Lambert, DG1
Braun, R1
Ruland, T1
Büche, I1
Waschke, KF1
Kerger, H1
Tatlisen, A1
Sofikerim, M1
Lahrtz, HG1
Lüllmann, H1
van Zwieten, PA1
Nava-Rivera, A1
Gutiérrez-López, A1
Férez, A1
Eisenberg, J1
Karlsson, JA1
Persson, CG1
Tuvemo, T1
Willdeck-Lund, G1
Saida, K1
Suzuki, A1
Taylor, WJ1
Wolf, A1
Young, JM1
Häkkinen, V1
Eskola, H1
Yli-Hankala, A1
Nurmikko, T1
Kolehmainen, S1
Lograno, MD1
Siro-Brigiani, G1
Cortese, I1
Sharaf, EM1
Abdel-Wahed, SA1
Youakim, S1
Saad, Y1
el-Khateeb, MS1
Taha, A1
Kaiser, H1
Niesel, HC1
Klimpel, L1
Bodenmueller, M1
McGlone, R1
Heyes, F1
Harris, P1
Tjioe, S1
Bianchi, CP1
Lund, JP1
Lamarre, Y1
Dietrichson, P1

Trials

3 trials available for prilocaine and Muscle Contraction

ArticleYear
Cutaneous anesthesia of the forearm enhances sensorimotor function of the hand.
    Journal of neurophysiology, 2013, Volume: 109, Issue:4

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Evoked Potentials, Motor; Female; Fingers; Forearm; Hu

2013
[Obturator nerve block for transurethral surgery. comparing ropivacaine 0.75 % vs. prilocaine 1 %].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2005, Volume: 40, Issue:7

    Topics: Aged; Amides; Anesthesia, General; Anesthetics, Local; Double-Blind Method; Female; Humans; Male; Mo

2005
Prilocaine in lumbosacral plexus block--general efficacy and comparison of nerve stimulation amplitude.
    Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:7

    Topics: Adult; Electric Stimulation; Female; Humans; Hypesthesia; Leg; Lumbosacral Plexus; Male; Motor Neuro

1992

Other Studies

16 other studies available for prilocaine and Muscle Contraction

ArticleYear
Liposomal formulations of prilocaine: effect of complexation with hydroxypropyl-ß-cyclodextrin on drug anesthetic efficacy.
    Journal of liposome research, 2010, Volume: 20, Issue:4

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Anesthetics, Local; Animals; beta-Cyclodextrins; Biocompatible Ma

2010
The effect of guanethidine and local anesthetics on the electrically stimulated mouse vas deferens.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:5

    Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Cocaine; Electric Stim

2002
Obturator nerve block and transurethral surgery for bladder cancer.
    Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 2007, Volume: 59, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Male; Middle Aged; Muscle Contra

2007
Accumulation and release of 14C-prilocaine by isolated guinea pig atria.
    European journal of pharmacology, 1967, Volume: 1, Issue:3

    Topics: Animals; Carbon Isotopes; Diaphragm; Guinea Pigs; Heart Atria; Hydrogen-Ion Concentration; In Vitro

1967
Influence of procaine, lidocaine and prilocaine on the adrenaline contraction of isolated strips of rabbit aorta.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 169, Issue:2

    Topics: Animals; Aorta; Drug Synergism; Epinephrine; In Vitro Techniques; Lidocaine; Muscle Contraction; Mus

1967
Local anesthetics selectively inhibit non-cholinergic neural contractions in guinea-pig airways.
    Acta physiologica Scandinavica, 1984, Volume: 120, Issue:3

    Topics: Anesthetics, Local; Animals; Bronchi; Electric Stimulation; Female; Guinea Pigs; Lidocaine; Male; Mu

1984
Smooth muscle effects of lidocaine, prilocaine, bupivacaine and etiodocaine on the human umbilical artery.
    Acta anaesthesiologica Scandinavica, 1982, Volume: 26, Issue:2

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Bupivacaine; Dose-Response Relati

1982
Mode of action of prilocaine on sarcoplasmic reticulum in skinned skeletal muscle fibers.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:3

    Topics: Animals; Calcium; In Vitro Techniques; Magnesium; Muscle Contraction; Prilocaine; Ranidae; Sarcoplas

1981
The interaction of amine local anaesthetics with muscarinic receptors.
    British journal of pharmacology, 1980, Volume: 71, Issue:1

    Topics: Amines; Anesthetics, Local; Animals; Brain; Carbachol; Guinea Pigs; In Vitro Techniques; Membranes;

1980
Which structures are sensitive to painful transcranial electric stimulation?
    Electromyography and clinical neurophysiology, 1995, Volume: 35, Issue:6

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Drug Combinations; Electric Stimulation;

1995
[Effects of lidocaine, mepivacaine and prilocaine on the detrusor muscle of the rat urinary bladder].
    Bollettino della Societa italiana di biologia sperimentale, 1979, Apr-15, Volume: 55, Issue:7

    Topics: Anesthetics, Local; Animals; Female; Lidocaine; Male; Mepivacaine; Muscle Contraction; Muscles; Pril

1979
Adrenergic blocking properties of Citanest.
    The Journal of the Egyptian Medical Association, 1977, Volume: 60, Issue:1-2

    Topics: Animals; Blood Pressure; Cats; Guinea Pigs; Heart Rate; Muscle Contraction; Myocardial Contraction;

1977
The use of muscle relaxant to supplement local anaesthetics for Bier's blocks.
    Archives of emergency medicine, 1988, Volume: 5, Issue:2

    Topics: Anesthesia, Local; Atracurium; Drug Evaluation; Electromyography; Fractures, Bone; Humans; Lidocaine

1988
Effects of local anesthetics on muscarinic sites of the isolated frog ventricle.
    European journal of pharmacology, 1969, Volume: 7, Issue:2

    Topics: Acetylcholine; Adrenergic beta-Antagonists; Anesthetics, Local; Anilides; Animals; Anura; Atropine;

1969
The importance of positive feedback from periodontal pressoreceptors during voluntary isometric contraction of jaw-closing muscles in man.
    Journal de biologie buccale, 1973, Volume: 1, Issue:4

    Topics: Electromyography; Feedback; Humans; Masticatory Muscles; Muscle Contraction; Periodontium; Pressorec

1973
Tonic ankle reflex in parkinsonian rigidity and in spasticity. The role of the fusimotor system.
    Acta neurologica Scandinavica, 1971, Volume: 47, Issue:2

    Topics: Adult; Aged; Anesthesia, Local; Ankle; Electric Stimulation; Electromyography; Female; Humans; Leg;

1971