Page last updated: 2024-11-03

prilocaine and Inflammation

prilocaine has been researched along with Inflammation in 6 studies

Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tan, KL1
Kurniawati, C1
Gold, MH1
Vieira dos Santos, R1
Metz, M1
Lima, HC1
Martus, P1
Maurer, M1
Pochapski, MT1
Neto, JL1
Jassen, JL1
Farago, PV1
Santos, FA1
YregÄrd, L1
Cassuto, J1
Tarnow, P1
Nilsson, U1
Rood, JP1
Caruana, PE1
Danford, M1
Pateromichelakis, S1
Rajewski, F1
Grudniewicz, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluating the Efficacy of an Ablative Fractional Carbon Dioxide Laser on Pathologic Symptoms in Pediatric Hypertrophic Scars: a Prospective Split-scar Controlled Trial[NCT04236167]6 participants (Actual)Interventional2020-11-01Terminated (stopped due to Lack of participants to enroll. Early findings not supportive of fractionated c02 laser improving scars in population studied when used alone.)
A Prospective, Randomized, Double-blind Study of the Anesthetic Efficacy of 3% Mepivacaine Plus 2% Lidocaine With 1:100,000 Epinephrine for Inferior Alveolar Nerve Blocks.[NCT01574807]Phase 4100 participants (Actual)Interventional2012-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Achieving Pulpal Anesthesia Success.

An electric pulp tester will be used to test the lower jaw teeth (molars, premolars, and incisors) for anesthesia (numbness) in 4-minute time cycles for 60 minutes. Measurements of less than 80 on the EPT is considered not numb (anesthesia failure). Readings of 80 equate to anesthetic success. (NCT01574807)
Timeframe: 60 minutes per injection sequence.

InterventionParticipants (Count of Participants)
Mepivacaine + Lidocaine44
Lidocaine + Lidocaine40

Trials

2 trials available for prilocaine and Inflammation

ArticleYear
Differential effects of skin nerves on allergic skin inflammation.
    Allergy, 2009, Volume: 64, Issue:3

    Topics: Anesthetics, Local; Double-Blind Method; Humans; Hypersensitivity; Inflammation; Lidocaine; Lidocain

2009
Prilocaine -- an investigation into its use in the presence of inflammation and in combination with lignocaine.
    Journal of dentistry, 1981, Volume: 9, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Animals; Clinical Trials as Topic; Double-Blind Method

1981

Other Studies

4 other studies available for prilocaine and Inflammation

ArticleYear
Low risk of postinflammatory hyperpigmentation in skin types 4 and 5 after treatment with fractional CO2 laser device.
    Journal of drugs in dermatology : JDD, 2008, Volume: 7, Issue:8

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Dermatitis, Phototoxic; Female; Humans; Hyperpigmentat

2008
Effect of lidocaine- and prilocaine-based topical anesthetics on the inflammatory exudates in subcutaneous tissue of rats.
    Anesthesia progress, 2012,Summer, Volume: 59, Issue:2

    Topics: Anesthetics, Combined; Anesthetics, Local; Animals; Biocompatible Materials; Capillary Permeability;

2012
Influence of local anaesthetics on inflammatory activity postburn.
    Burns : journal of the International Society for Burn Injuries, 2003, Volume: 29, Issue:4

    Topics: Administration, Topical; Anesthetics, Local; Animals; Burns; Free Radicals; Inflammation; Leukotrien

2003
[The author's own method of local anesthesia for skin incision around implants during limb lengthening].
    Chirurgia narzadow ruchu i ortopedia polska, 1997, Volume: 62, Issue:2

    Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Bone Lengthening; Child; Child, Preschool; Cost C

1997