Page last updated: 2024-11-03

prilocaine and Hypesthesia

prilocaine has been researched along with Hypesthesia in 4 studies

Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.

Hypesthesia: Absent or reduced sensitivity to cutaneous stimulation.

Research Excerpts

ExcerptRelevanceReference
"There were no reports of numbness of the tongue, lip, or cheek, neither were there any adverse local reactions in the oral mucosa."2.70The anesthetic onset and duration of a new lidocaine/prilocaine gel intra-pocket anesthetic (Oraqix) for periodontal scaling/root planing. ( Friskopp, J; Isacsson, G; Nilsson, M, 2001)
" The efficacy of the sciatic block proved to be extremely high (> 95%), its success depending on the dosage of the local anaesthetic and correct execution of the peripheral nerve stimulation."2.67Prilocaine in lumbosacral plexus block--general efficacy and comparison of nerve stimulation amplitude. ( Bodenmueller, M; Kaiser, H; Klimpel, L; Niesel, HC, 1992)
"Chronic pain is often a symptom after local anaesthetic-induced nerve injury."1.36Trigeminal nerve injuries in relation to the local anaesthesia in mandibular injections. ( Adey-Viscuso, D; Meechan, JG; Renton, T; Yilmaz, Z, 2010)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Renton, T1
Adey-Viscuso, D1
Meechan, JG1
Yilmaz, Z1
McLean, C1
Reader, A1
Beck, M1
Meryers, WJ1
Friskopp, J1
Nilsson, M1
Isacsson, G1
Kaiser, H1
Niesel, HC1
Klimpel, L1
Bodenmueller, M1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is the Direct Inferior Alveolar Nerve Block Required for Third Lower Molar Extraction?[NCT03443726]120 participants (Actual)Interventional2017-06-10Completed
A Prospective, Randomized, Double-blind Study of the Anesthetic Efficacy of 3% Mepivacaine Plus 2% Lidocaine With 1:100,000 Epinephrine for Inferior Alveolar Nerve Blocks.[NCT01574807]Phase 4100 participants (Actual)Interventional2012-05-31Completed
Inferior Alveolar Nerve Block: a Novel Intraoral Technique Depends on Extraoral Landmarks[NCT04093713]65 participants (Anticipated)Interventional2019-09-14Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Achieving Pulpal Anesthesia Success.

An electric pulp tester will be used to test the lower jaw teeth (molars, premolars, and incisors) for anesthesia (numbness) in 4-minute time cycles for 60 minutes. Measurements of less than 80 on the EPT is considered not numb (anesthesia failure). Readings of 80 equate to anesthetic success. (NCT01574807)
Timeframe: 60 minutes per injection sequence.

InterventionParticipants (Count of Participants)
Mepivacaine + Lidocaine44
Lidocaine + Lidocaine40

Trials

3 trials available for prilocaine and Hypesthesia

ArticleYear
An evaluation of 4% prilocaine and 3% mepivacaine compared with 2% lidocaine (1:100,000 epinephrine) for inferior alveolar nerve block.
    Journal of endodontics, 1993, Volume: 19, Issue:3

    Topics: Adult; Analysis of Variance; Anesthesia, Dental; Dental Pulp; Female; Humans; Hypesthesia; Lidocaine

1993
An evaluation of 4% prilocaine and 3% mepivacaine compared with 2% lidocaine (1:100,000 epinephrine) for inferior alveolar nerve block.
    Journal of endodontics, 1993, Volume: 19, Issue:3

    Topics: Adult; Analysis of Variance; Anesthesia, Dental; Dental Pulp; Female; Humans; Hypesthesia; Lidocaine

1993
An evaluation of 4% prilocaine and 3% mepivacaine compared with 2% lidocaine (1:100,000 epinephrine) for inferior alveolar nerve block.
    Journal of endodontics, 1993, Volume: 19, Issue:3

    Topics: Adult; Analysis of Variance; Anesthesia, Dental; Dental Pulp; Female; Humans; Hypesthesia; Lidocaine

1993
An evaluation of 4% prilocaine and 3% mepivacaine compared with 2% lidocaine (1:100,000 epinephrine) for inferior alveolar nerve block.
    Journal of endodontics, 1993, Volume: 19, Issue:3

    Topics: Adult; Analysis of Variance; Anesthesia, Dental; Dental Pulp; Female; Humans; Hypesthesia; Lidocaine

1993
The anesthetic onset and duration of a new lidocaine/prilocaine gel intra-pocket anesthetic (Oraqix) for periodontal scaling/root planing.
    Journal of clinical periodontology, 2001, Volume: 28, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Combined; Anesthetics, Local; Dental Scalin

2001
Prilocaine in lumbosacral plexus block--general efficacy and comparison of nerve stimulation amplitude.
    Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:7

    Topics: Adult; Electric Stimulation; Female; Humans; Hypesthesia; Leg; Lumbosacral Plexus; Male; Motor Neuro

1992

Other Studies

1 other study available for prilocaine and Hypesthesia

ArticleYear
Trigeminal nerve injuries in relation to the local anaesthesia in mandibular injections.
    British dental journal, 2010, Volume: 209, Issue:9

    Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Chin; Cranial Nerve Injuries; Female; Gingiva; H

2010