Page last updated: 2024-11-03

prilocaine and Hyperidrosis

prilocaine has been researched along with Hyperidrosis in 6 studies

Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dixit, S1
Lowe, P1
Fischer, G1
Lim, A1
Shi, LL1
Sargen, MR1
Chen, SC1
Arbiser, JL1
Pollack, BP1
Blaheta, HJ1
Vollert, B1
Zuder, D1
Rassner, G1
Ponce-Olivera, RM1
Tirado-Sánchez, A1
Arellano-Mendoza, MI1
León-Dorantes, G1
Kassian-Rank, S1
Hasche, E1
Hagedorn, M1
Sattler, G1
Juhlin, L1
Evers, H1
Broberg, F1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment Prior to Injection and Biopsy of the Vulva[NCT03444727]13 participants (Actual)Interventional2018-02-19Terminated (stopped due to Not enough enrollment)
Randomized, Single Center, Masked Study Comparing the Efficacy of Botulinum Toxin Type A Injection After Topical Anesthesia Versus Petrolatum Ointment[NCT03799484]Phase 414 participants (Actual)Interventional2019-01-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Duration of Botulinum Toxin Type A Effect

Loss of Botulinum Toxin Type A effect is defined as return of baseline frontalis muscle function (function prior to injection) as indicated by eyebrow excursion measurement within 2 millimeters of baseline value. (NCT03799484)
Timeframe: week 16

Interventionweeks (Mean)
Topical Anesthesia14.2857
Petrolatum15.2857

Eyebrow Excursion

(NCT03799484)
Timeframe: week 16

Interventionmillimeters (Mean)
Topical Anesthesia8.21
Petrolatum8.07

Eyebrow Excursion

Participants will be asked to raise the brows, and the excursion of the brow from resting position to maximum elevation will be measured in millimeters. (NCT03799484)
Timeframe: Baseline

Interventionmillimeters (Mean)
Topical Anesthesia10.57
Petrolatum10.57

Eyebrow Excursion

Participants will be asked to raise the brows, and the excursion of the brow from resting position to maximum elevation will be measured in millimeters. (NCT03799484)
Timeframe: Week 2

Interventionmillimeters (Mean)
Topical Anesthesia3.46
Petrolatum3.43

Eyebrow Excursion

Participants will be asked to raise the brows, and the excursion of the brow from resting position to maximum elevation will be measured in millimeters. (NCT03799484)
Timeframe: Week 6

Interventionmillimeters (Mean)
Topical Anesthesia5.96
Petrolatum5.68

Number of Participants Who Perceive a Difference in Efficacy Between the 2 Sides of Their Face

Participants will be asked if there is a noticeable difference between the 2 sides of their face. (NCT03799484)
Timeframe: Week 16

InterventionParticipants (Count of Participants)
All Participants0

Number of Participants Who Perceive a Difference in Efficacy Between the 2 Sides of Their Face

Participants will be asked if there is a noticeable difference between the 2 sides of their face. (NCT03799484)
Timeframe: Week 2

InterventionParticipants (Count of Participants)
All Participants3

Number of Participants Who Perceive a Difference in Efficacy Between the 2 Sides of Their Face

Participants will be asked if there is a noticeable difference between the 2 sides of their face. (NCT03799484)
Timeframe: Week 6

InterventionParticipants (Count of Participants)
All Participants2

Perception of Pain Immediately After Injection as Assessed by a Visual Analogue Scale

A visual analogue scale will be used to assess pain. The scale ranges from 0 (no pain) to 10 (the worse pain possible), with lower scores indicating a better outcome. (NCT03799484)
Timeframe: Immediately after botox injection

Interventionunits on a scale (Mean)
Topical Anesthesia2.43
Petrolatum3.96

Trials

1 trial available for prilocaine and Hyperidrosis

ArticleYear
Inhibition of hyperhidrosis by topical application of a local anesthetic composition.
    Acta dermato-venereologica, 1979, Volume: 59, Issue:6

    Topics: Administration, Topical; Adolescent; Adult; Axilla; Drug Combinations; Female; Hand; Humans; Hyperhi

1979

Other Studies

5 other studies available for prilocaine and Hyperidrosis

ArticleYear
Ice anaesthesia in procedural dermatology.
    The Australasian journal of dermatology, 2013, Volume: 54, Issue:4

    Topics: Adult; Aluminum; Anesthesia, Local; Australia; Botulinum Toxins, Type A; Cryoanesthesia; Dermatology

2013
Effective local anesthesia for onabotulinumtoxin A injections to treat hyperhidrosis associated with traumatic amputation.
    Dermatology online journal, 2016, Jun-15, Volume: 22, Issue:6

    Topics: Acetylcholine Release Inhibitors; Administration, Cutaneous; Amputation Stumps; Amputation, Traumati

2016
Intravenous regional anesthesia (Bier's block) for botulinum toxin therapy of palmar hyperhidrosis is safe and effective.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2002, Volume: 28, Issue:8

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Local; Botulinum Toxins, Type A; Female; Hand; Humans;

2002
Palmar hyperhidrosis. Safety efficacy of two anaesthetic techniques for botulinum toxin therapy.
    Dermatology online journal, 2006, Feb-28, Volume: 12, Issue:2

    Topics: Anesthesia, Local; Anesthetics, Local; Autonomic Nerve Block; Botulinum Toxins, Type A; Hand; Humans

2006
[Subcutaneous sweat gland suction curettage in tumescent local anesthesia in hyperhidrosis axillaris].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1997, Volume: 48, Issue:11

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Axilla; Curettage; Female; Humans; Hyperhidrosis; Male

1997