prilocaine has been researched along with Erythema in 14 studies
Prilocaine: A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry.
prilocaine : An amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.
Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to compare the efficacy of topical piroxicam and EMLA cream on pain control and subsequent inflammation in neodymium:yttrium-aluminum-garnet (Nd:YAG) 1,064 nm laser hair removal in female volunteers." | 9.14 | A clinical comparison of topical piroxicam and EMLA cream for pain relief and inflammation in laser hair removal. ( Akinturk, S; Eroglu, A, 2009) |
| "Pain scores with piroxicam gel were higher on cannulation and on advancement of the cannula (P < 0." | 9.10 | Piroxicam gel, compared to EMLA cream is associated with less pain after venous cannulation in volunteers. ( Dutta, A; Puri, GD; Wig, J, 2003) |
| "The aim of this study was to compare the efficacy of topical piroxicam and EMLA cream on pain control and subsequent inflammation in neodymium:yttrium-aluminum-garnet (Nd:YAG) 1,064 nm laser hair removal in female volunteers." | 5.14 | A clinical comparison of topical piroxicam and EMLA cream for pain relief and inflammation in laser hair removal. ( Akinturk, S; Eroglu, A, 2009) |
| "To examine the efficacy and safety of a new topical anesthetic containing a disinfection ingredient (LidoDin cream) in reducing the pain associated with venipuncture by comparing it with the proven eutectic mixture of lidocaine 2." | 5.14 | Lidocaine-based topical anesthetic with disinfectant (LidoDin) versus EMLA for venipuncture: a randomized controlled trial. ( Hadash, A; Kassis, I; Knaani-Levinz, H; Shachor-Meyouhas, Y; Shavit, I, 2009) |
| "Pain scores with piroxicam gel were higher on cannulation and on advancement of the cannula (P < 0." | 5.10 | Piroxicam gel, compared to EMLA cream is associated with less pain after venous cannulation in volunteers. ( Dutta, A; Puri, GD; Wig, J, 2003) |
| "Pain was evaluated on a visual analog scale (VAS, 0-10)." | 2.69 | [Efficacy of EMLA cream, effect of time and place of application]. ( Cano Serrano, ME; Martínez-Tellería, A; Rufino Ruiz, J, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Li, L | 1 |
| Cai, B | 1 |
| Li, H | 1 |
| Wei, J | 1 |
| Tao, L | 1 |
| Ma, P | 1 |
| Akinturk, S | 1 |
| Eroglu, A | 1 |
| Shavit, I | 1 |
| Hadash, A | 1 |
| Knaani-Levinz, H | 1 |
| Shachor-Meyouhas, Y | 1 |
| Kassis, I | 1 |
| Fasting, S | 1 |
| Gisvold, SE | 1 |
| Dutta, A | 1 |
| Puri, GD | 1 |
| Wig, J | 1 |
| Moppett, IK | 1 |
| Szypula, K | 1 |
| Yeoman, PM | 1 |
| Lawson, RA | 1 |
| Smart, NG | 1 |
| Gudgeon, AC | 1 |
| Morton, NS | 1 |
| Hewitt, T | 1 |
| Scales, K | 1 |
| Martínez-Tellería, A | 1 |
| Cano Serrano, ME | 1 |
| Rufino Ruiz, J | 1 |
| Mattsson, U | 1 |
| Cassuto, J | 1 |
| Jontell, M | 1 |
| Jönsson, A | 1 |
| Sinclair, R | 1 |
| Tarnow, P | 1 |
| Khatri, KA | 1 |
| Machado, A | 1 |
| Magro, C | 1 |
| Davenport, S | 1 |
| Dong, H | 1 |
| Kerl, H | 1 |
| Cerroni, L | 1 |
| Villada, G | 1 |
| Zetlaoui, J | 1 |
| Revuz, J | 1 |
| Bjerring, P | 1 |
| Andersen, PH | 1 |
| Arendt-Nielsen, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison Between the Effects of Lidocaine Prilocaine Cream and Lidocaine Injection on Reduction of Perineal Pain During Episiotomy and Perineum Repair in Vaginal Delivery: Randomized Control Trial[NCT05891132] | 60 participants (Anticipated) | Interventional | 2023-09-01 | Not yet recruiting | |||
| A Comparison of Amethocaine Creams Versus Liposomal Lidocaine Cream as Pain Reliever Prior to Venipuncture in Children at the Paediatric Emergency Department.[NCT00353002] | 0 participants (Actual) | Interventional | 2006-07-31 | Withdrawn | |||
| The Efficacy of the Eutectic Mixture of Local Anesthetics (EMLA) Cream Versus the Synera Patch for Pain Reduction During Venipuncture in Children[NCT00530803] | Phase 2 | 100 participants (Actual) | Interventional | 2007-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain experienced by the participants at tourniquet placement. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: before venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 41 | 6 | 2 | 1 | 0 | 0 |
| Synera Patch | 37 | 6 | 5 | 1 | 1 | 0 |
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain participants were experiencing 5 minutes after the venipuncture was completed. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: 5 minutes post venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 45 | 3 | 1 | 1 | 0 | 0 |
| Synera Patch | 45 | 4 | 1 | 0 | 0 | 0 |
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain experienced by the participants at needle insertion. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: during needle insertion
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 32 | 14 | 2 | 2 | 0 | 0 |
| Synera Patch | 25 | 12 | 9 | 2 | 2 | 0 |
The Numerical Rating Scale (NRS) is a 6-point rating scale where 0= no pain and 5 = worst pain. Parents reported their own subjective evaluation of participants pain level. Each participant had only one parental assessment. Total number of parental assessment for each pain level on the 6-point NRS is reported as total number of participants experiencing that pain level. (NCT00530803)
Timeframe: immediately after venipuncture is completed
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| number of participants with NRS=0 (no pain) | number of participants with NRS=1 | number of participants with NRS=2 | number of participants with NRS=3 | number of participants with NRS=4 | number of participants with NRS=5 | |
| EMLA Cream | 42 | 6 | 1 | 1 | 0 | 0 |
| Synera Patch | 41 | 5 | 1 | 2 | 0 | 1 |
"Participants were asked to report their level of pain using a 6-point Wong-Baker FACES Pain Rating Scale ranging from 0, no pain, to 5, the most pain you can have. The Wong-Baker FACES Pain Rating Scale is a validated tool for measuring pain in patients as young as 3 years old. A FACES pain score less than or equal to 2 is considered no pain to mild pain, and is clinically acceptable. Studies have shown average FACES pain scores for children receiving vascular access with placebo to be 2.2 to 3.5." (NCT00530803)
Timeframe: immediately after completion of venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants with FACES Score = 0 (No pain) | Participants with FACES Score = 1 | Participants with FACES Score = 2 | Participants with FACES Score = 3 | Participants with FACES Score = 4 | Participants with FACES Score = 5 | |
| EMLA Cream | 42 | 6 | 2 | 0 | 0 | 0 |
| Synera Patch | 38 | 8 | 3 | 1 | 0 | 0 |
9 trials available for prilocaine and Erythema
| Article | Year |
|---|---|
A clinical comparison of topical piroxicam and EMLA cream for pain relief and inflammation in laser hair removal.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroi | 2009 |
Lidocaine-based topical anesthetic with disinfectant (LidoDin) versus EMLA for venipuncture: a randomized controlled trial.
Topics: Adolescent; Adult; Anesthetics, Combined; Anesthetics, Local; Child; Disinfectants; Edema; Erythema; | 2009 |
Statistical process control methods allow the analysis and improvement of anesthesia care.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Catheterization, Peripheral | 2003 |
Piroxicam gel, compared to EMLA cream is associated with less pain after venous cannulation in volunteers.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Catheterization, Peripheral | 2003 |
Comparison of EMLA and lidocaine iontophoresis for cannulation analgesia.
Topics: Adult; Aged; Analgesia; Anesthetics, Combined; Anesthetics, Local; Catheterization, Peripheral; Doub | 2004 |
Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; | 1995 |
Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; | 1995 |
Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; | 1995 |
Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; | 1995 |
[Efficacy of EMLA cream, effect of time and place of application].
Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Double-Blind Method; Elbow; Emulsions; Erythema; F | 1999 |
Digital image analysis of erythema development after experimental thermal injury to human skin: effect of postburn topical local anesthetics (EMLA).
Topics: Administration, Topical; Adult; Anesthetics, Combined; Anesthetics, Local; Burns; Erythema; Humans; | 1999 |
Local blanching after epicutaneous application of EMLA cream. A double-blind randomized study among 50 healthy volunteers.
Topics: Administration, Cutaneous; Anesthetics, Local; Double-Blind Method; Drug Combinations; Erythema; Hum | 1990 |
5 other studies available for prilocaine and Erythema
| Article | Year |
|---|---|
Dermal effects and pharmacokinetic evaluation of the lidocaine/prilocaine cream in healthy Chinese volunteers.
Topics: Anesthetics, Local; Drug Combinations; East Asian People; Erythema; Healthy Volunteers; Humans; Lido | 2023 |
Prolonged contact with topical anaesthetic cream: a case report.
Topics: Administration, Topical; Anesthetics, Local; Erythema; Humans; Infant; Lidocaine; Lidocaine, Priloca | 1998 |
Laser peel: facial rejuvenation with a superficial erbium:YAG laser treatment.
Topics: Adult; Aged; Anesthetics, Local; Erbium; Erythema; Female; Humans; Laser Therapy; Lidocaine; Lidocai | 2000 |
EMLA cream-induced irritant contact dermatitis.
Topics: Acrodermatitis; Administration, Topical; Anesthetics, Local; Child; Dermatitis, Contact; Diagnosis, | 2002 |
Vascular response of human skin after analgesia with EMLA cream.
Topics: Adult; Analgesia; Anesthetics, Local; Drug Combinations; Drug Eruptions; Erythema; Female; Humans; L | 1989 |